Main Article Content

Abstract

Type 2 diabetes mellitus (DM) is the 10th leading cause of death in the world and had a risk 4.06 times greater to have cardiovascular disease (CVD). Fasting plasma glucose and 2-hours postprandial glucose level as diagnostic tests to evaluate DM and also as a predictive factors to CVD. This research uses descriptive analytic research with cross sectional design. The subject of this study is Type 2 DM patients came to Dr Soetomo hospital from January-October 2014. Data was recorded from medical records of patients and was analyzed with Chi Square test with p<0.05. As result, there is 102 Type 2 DM patients with 36 patients have CVD manifestation and 66 patients without complication. There is a significant association between fasting plasma glucose (FPG), 2-hours postprandial glucose (2hPPG) level, and CVD manifestation (p=0.00). So FPG and 2hPPG have a significant association with CVD manifestation. There are other factors that influencing the formation of CVD, hence, further research is needed.

Keywords

Type 2 Diabetes Mellitus cardiovascular disease fasting plasma glucose 2-hours postprandial glucose

Article Details

How to Cite
Marchelia, L. Z., Purwati, P., & Wironegoro, R. (2017). HIGH BLOOD GLUCOSE LEVEL INCREASE CARDIOVASCULAR DISEASE RISK IN TYPE 2 DIABETES MELLITUS. Folia Medica Indonesiana, 52(2), 127–130. https://doi.org/10.20473/fmi.v52i2.5228

References

  1. Fí¦rch K (2014). Gender and T2DM. Available from http://www.diapedia.org/type-2-diabetes-mellitus/ 3104972816/gender-and-t2dm. Accessed November 11, 2014
  2. Fowler MJ (2008). Microvascular and macrovascular complications. Diabetes Foundation 26, 77-81
  3. Kitasato L, Tojo T, Hatakeyama Y, Kameda R, Hashikata T, Yamaoka-Tojo M (2012). Postprandial hyperglycemia and endothelial function in type 2 diabetes: focus on mitiglinide. Cardiovascular Diabetology 11, 79
  4. Mannucci E, Dicembrini I, Lauria A, Pozzilli P (2013). Is glucose control important for prevention of cardiovascular disease in diabetes?. Diabetes Care 36, S259-S263
  5. Mendelsohn ME and Karas RH (1999). The protective effects of estrogen on the cardiovascular system. N Engl J Med 340, 1801-1811
  6. Ministry of Health, Republic of Indonesia (2007). Riskesdas, Jakarta, Health Department, Republic of Indonesia
  7. Park C, Guallar E, Linton JA, Lee DC, Jang Y, Son DK, Han EJ, Baek SJ, Yun YD, Jee SH, Samet JM (2013). Fasting glucose level and the risk of incident atherosclerotic cardiovascular diseases. Diabetes Care 36, 1988-1993
  8. Shimodaira M, Niwa T, Nakajima K, Kobayashi M, Hanyu N, Nakayama T (2013). Correlation between mean platelet volume and fasting plasma glucose levels in prediabetic and normoglycemic individuals. Cardiovascular Diabetology 12, 14
  9. Trovati M (2011). Postprandial blood glucose predicts cardiovascular events and all-cause mortality in type 2 diabetes in a 14-year follow-up: lessons from the San Luigi Gonzaga Diabetes Study. Diabetes Care 34, 2237-2243