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Submitted
28 December 2017
Accepted
28 December 2017
Published
28 December 2017
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Abstract

Acne vulgaris (AV) is an inflammation of pilosebaceous unit especially in young adult. The pathophysiology is the elevation of sebum production, keratinization of abnormal pilocebaseous follicles, and inflammation caused by immune response to Propionibacterium acnes. Therapy combination of oral antibiotics (doxycycline) and physical therapy (blue light) in moderate-severe acne is one option to reduce antibiotic resistance. Doxycycline is a commonly antibiotic used. The effects of photosensitive can increase the penetration of blue light by sebaceous glands. There was a total decrease in sebum and clinical improvement of combination therapy of blue light and doxycycline in seven patients. The combination therapy has been shown to improve its therapeutic effect, but more clinical trials are needed to prove the effectiveness of blue light with doxycycline than without blue light.

Keywords

Acne vulgaris doxycycline blue light

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  • Folia Medica Indonesiana is a scientific peer-reviewed article which freely available to be accessed, downloaded, and used for research purposes. Folia Medica Indonesiana (p-ISSN: 2541-1012; e-ISSN: 2528-2018) is licensed under a Creative Commons Attribution 4.0 International License. Manuscripts submitted to Folia Medica Indonesiana are published under the terms of the Creative Commons License. The terms of the license are:

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How to Cite
Listiawan, M. Y., Prakoeswa, C. R. S., Handamari, D. A., & Indira, R. (2017). EFFECTS OF BLUE LIGHT EMITTING DIODE (LED) AND DOXYCYCLINE TO SEBACEOUS GLAND IN ACNE VULGARIS. Folia Medica Indonesiana, 53(4), 272–275. https://doi.org/10.20473/fmi.v53i4.7160
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References

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