NUTRITION AS A RISK FACTOR OF CHILD LEPROSY IN GRESIK DISTRICT 2019
Downloads
Background: Indonesia's annual increase in leprosy is a serious health problem. In east Java, child leprosy cases spread in several counties/cities, the number of new cases of child leprosy cases has been raised in Gresik District from 2015 until 2019. Purpose: This study analyzed characteristics, BCG vaccine status, nutritional status and home environment, the correlated risk factors to child leprosy in Gresik District. Methods: This study used a design population-based matched case-control design and analysis data using computer computing. The variables for this research were characteristics (age, sex, and education) and BCG vaccine status (BCG scar and without BCG scar), nutritional status classified as Body Mass Index (BMI)(normal and thin) and protein (albumin and Hb serum), and home environment (wall, ceiling, floor, humidity, ventilation, and density of occupancy). It was conducted in October 2019-February 2020 using a questionnaire, observation and measurements. The total sample was 36 respondents, of which the number of the case was 18, and the control was 18. Data were analyzed using the Logistic Regression method entered with a 95% CI and an OR. Results: Home environment had not correlated to leprosy cases of children. The completeness of BCG vaccine status correlated to children's leprosy cases (p=0.02). BMI had correlated to leprosy cases of children (p=0.01). The most influential variable was the completeness protein of albumin serum (Odds Ratio (OR) =9.10; 95%CI=1.11-41.44; p=0.01). Conclusion: The most dominant risk factor correlated with the incidence of leprosy is the serum albumin level.
Alotaibi, M. H., Bahammam, S. A., Bahnassy, A. A., Hassan, I. S., Alothman, A. F., & Alkayal, A. M. (2016). The demographic and clinical characteristics of leprosy in Saudi Arabia. Journal of Infection and Public Health, 9(5), 611–617. https://doi.org/10.1016/j.jiph.2015.12.015
Amalia, H., Tabri, F., Vitayani, S., & Petellongi, I. (2017). Hemoglobin and ferritin serum levels on leprosy patients before multi drug therapy - world health organization (Mdt - Who) compared with healthy control group. International Journal of Sciences: Basic and Applied Research, 36(4), 74–82.
Barreto, J. G., Andrey, M., Frade, C., Filho, F. B., Batista, M., Spencer, J. S., & Salgado, C. G. (2017). Leprosy in children. Current Infectious Disease Reports, 19(23), 1–8. https://doi.org/10.1007/s11908-017-0577-6
Bawazir, L. A. A. (2020). Limitations of serum albumin level as a marker of nutritional status in hemodialysis patients. Bali Medical Journal, 9(1), 149–154. https://doi.org/10.15562/bmj.v9i1.1515
Cederholm, T., Bosaeus, I., Barazzoni, R., Bauer, J., Gossum, A. Van, Klek, S., ... Singer, P. (2015). Diagnostic criteria for malnutrition e an ESPEN consensus statement. Clinical Nutrition, 34(3), 335–340. https://doi.org/10.1016/j.clnu.2015.03.001
East Java Provincial Health Office. (2019). East Java Provincial health profile at 2018. East Java Provincial Health Office. Surabaya. Retrieved August, 26, 2020, from https://dinkes.jatimprov.go.id/userfile/dokumen/BUKU PROFIL KESEHATAN JATIM 2018.pdf
Lee, J. L., Oh, E. S., Lee, R. W., & Finucane, T. E. (2015). Serum albumin and prealbumin in calorically restricted, nondiseased individuals: a systematic review. The American Journal of Medicine, 128(9), 1023.e1-1023.e22. https://doi.org/10.1016/j.amjmed.2015.03.032
Lobo, C., Aithal, V., & Raj, R. (2019). Nutritional assessment in patients with leprosy. Indian Journal of Leprosy, 91(4), 315–323.
Marks, P. W. (2016). Evaluation of anemia in children and adults. In S. A. Abutalib, J. M. Connors, & M. V Ragni (Eds.), Nonmalignant hematology: expert clinical review: questions and answers (pp. 3–12). USA: Springer. https://doi.org/10.1007/978-3-319-30352-9_1
Mayangsari, R., Zulkarnain, I., & Setyaningrum, T. (2016). The profile of interferon- É£ and BCG scar as an immune response reflection in children with leprosy. Berkala Ilmu Kesehatan Kulit dan Kelamin, 28(3), 1–8. http://dx.doi.org/10.20473/bikk.V28.3.2016.202-209
Noordende, A. T. V., Korfage, I. J., Lisam, S., Arif, M. A., Kumar, A., & Van Brakel, W. H. (2019). The role of perceptions and knowledge of leprosy in the elimination of leprosy: a baseline study in Fatehpur District, Northern India. PLoS Neglected Tropical Diseases, 13(4), 1–16. https://doi.org/10.1371/journal.pntd.0007302
Oliveira, M. P. De, Sousa, J. R. De, Araujo, R. S. De, Aarí£o, T. L. D. S., & Quaresma, J. A. S. (2017). Protein profile of leprosy patients with plantar ulcers from the Eastern Amazon region. Infectious Diseases of Poverty, 6, 1–8. https://doi.org/10.1186/s40249-017-0318-y
Patmawati, P., & Setiani, N. O. (2015). Environment risk factors and behaviors of leprosy patients in Polewali Mandar Regency. Buletin Penelitian Kesehatan, 43(3), 207–212. https://doi.org/10.22435/bpk.v43i3.4348.207-212
Richardus, R., Alam, K., Kundu, K., Chandra Roy, J., Zafar, T., Chowdhury, A. S., ... Richardus, J. H. (2019). Effectiveness of single-dose rifampicin after BCG vaccination to prevent leprosy in close contacts of patients with newly diagnosed leprosy: a cluster randomized controlled trial. International Journal of Infectious Diseases, 88, 65–72. https://doi.org/10.1016/j.ijid.2019.08.035
Romero-Montoya, M., Beltran-Alzate, J. C., & Cardona-Castro, N. (2017). Evaluation and monitoring of mycobacterium leprae transmission in household contacts of patients with hansen's disease in Colombia. PLoS Neglected Tropical Diseases, 11(1), 1–11. https://doi.org/10.1371/journal.pntd.0005325
Saha, G., Mandal, N. K., & Dutta, R. N. (2015). Current perceptions and practices (KAP) about leprosy among leprosy patients: a comparative study between high prevalent & low prevalent districts of West Bengal. Indian Journal of Leprosy, 87(1), 1–16.
Santos, S. D., Penna, G. O., Costa, M. da C. N., Natividade, M. S., & Teixeira, M. G. (2016). Leprosy in children and adolescents under 15 years old in an urban centre in Brazil. Memorias Do Instituto Oswaldo Cruz, 111(6), 359–364. https://doi.org/10.1590/0074-02760160002
Soedjana, H., Bowo, S. A., Putri, N. M., & Davita, T. R. (2020). Serum albumin level difference in burn injury after tangential excision: a prospective cohort study. Annals of Medicine and Surgery, 52, 1–4. https://doi.org/10.1016/j.amsu.2020.02.007
Thalacker-Mercer, A. E., Johnson, C. A., Yarasheski, K. E., Carnell, N. S., & Campbell, W. W. (2007). Nutrient ingestion, protein intake, and sex, but not age, affect the albumin synthesis rate in humans. The Journal of Nutrition, 137(7), 1734–1740. https://doi.org/10.1093/jn/137.7.1734
Venkatakrishnan, Y., Thangaraju, P., Jeganathan, S., Sankaran, S. K., & Kannan, R. (2020). Nutritional status and morbidity profile of children with leprosy contact in a rural community. Tropical Doctor, 50(4), 311–317. https://doi.org/10.1177/0049475520932193
Wagenaar, I., van Muiden, L., Alam, K., Bowers, R., Hossain, M. A., Kispotta, K., & Richardus, J. H. (2015). Diet-related risk factors for leprosy: a case-control study. PLoS Neglected Tropical Diseases, 9(5), 1–15. https://doi.org/10.1371/journal.pntd.0003766
World Health Organization. (2020). Global leprosy (Hansen disease) update, 2019: time to step-up prevention initiatives. Weekly Epidemiological Record, 95, 417–440
- Every manuscript submitted to must observe the policy and terms set by the Jurnal Berkala Epidemiologi
- Publication rights to manuscript content published by the Jurnal Berkala Epidemiologi is owned by the journal with the consent and approval of the author(s) concerned. (download copyright agreement)
- Complete texts of electronically published manuscripts can be accessed free of charge if used for educational and research purposes according to copyright regulations.
JBE by Universitas Airlangga is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
