THE RELATIONSHIP OF DIABETES MELLITUS AND HYPERTENSION WITH MORTALITY IN COVID-19 PATIENTS
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Background: Coronavirus disease 2019 (COVID-19) can infect the human respiratory system and causes 6.93% of all deaths in East Java Province. Comorbid diabetes mellitus and hypertension can exacerbate COVID-19 patients. Purpose: This study aims to analyze the relationship between diabetes mellitus and hypertension with mortality in COVID-19 Patients in Lamongan District. Methods: This study used an analytic observational study with a cross-sectional design. The study population was patients diagnosed with COVID-19 and registered at Lamongan District Health Office from April to August 2020, as many as 412 patients. The study sample was 93 patients who were taken by simple random sampling. The dependent variable in the study was the incident of mortality in COVID-19 patients. The independent variables in the study were gender, age, hypertension, and diabetes mellitus. Data analysis was using the chi-square test. Results: The variables studied that had a relationship with mortality in COVID-19 patients were age ≥ 60 years (p = 0.02; PR = 3.23; 95% CI = 1.29 <PR <8.10) and diabetes mellitus (p = 0.03; PR = 3.20; 95% CI = 1.23 <PR <8.36). The variables studied that did not have a relationship with mortality in COVID-19 patients were gender (p = 0.30; PR = 1.72; 95% CI = 0.74 <PR <4.03) and hypertension (p = 0.72; PR = 1.37; 95% CI = 0.34 <PR <5.48). Conclusion: Age and diabetes mellitus are significantly associated with mortality in COVID-19 patients, but sex and hypertension are not significantly associated with mortality in COVID-19 patients.
BPS Kabupaten Lamongan. (2015). Jumlah Kasus 10 Penyakit Terbanyak di Kabupaten Lamongan Tahun 2015. https://lamongankab.bps.go.id/statictable/2016/11/05/466/-jumlah-kasus-10-penyakit-terbanyak-di-kabupaten-lamongan-2015.html
CDC. (2020). Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019 ” United States, February 12–March 28, 2020. MMWR. Morbidity and Mortality Weekly Report, 69(13), 382–386. https://doi.org/10.15585/mmwr.mm6913e2
Dinkes Kabupaten Lamongan. (2021). COVID-19 Center Lamongan Dinas Kesehatan. https://lamongankab.go.id/dinkes/covid-19-center-lamongan/
Ganesan, S. K., Venkatratnam, P., Mahendra, J., & Devarajan, N. (2020). Increased Mortality of COVID-19 Infected Diabetes Patients: Role of Furin Proteases. International Journal of Obesity, 44(12), 2486–2488. https://doi.org/10.1038/s41366-020-00670-9
Grace, C. (2020). Manifestasi Klinis dan Perjalanan Penyakit pada Pasien COVID-19. Universitas Lampung: Fakultas Kedokteran, 9(1).
Huang, I., Lim, M. A., & Pranata, R. (2020). Diabetes Mellitus is Associated with Increased Mortality and Severity of Disease in COVID-19 Pneumonia, A Systematic Review , Meta-analysis, and Meta Regression. January.
Kemenkes RI. (2020). Pedoman Pencegahan dan Pengendalian Coronavirus Disease (COVID-19) Revisi 05.
Kemenkes RI. (2021). Infeksi Emerging Kementerian Kesehatan RI. https://infeksiemerging.kemkes.go.id/dashboard/covid-19
Lippi, G., Wong, J., & Henry, B. M. (2020). Hypertension in Patients with Coronavirus Disease 2019 (COVID-19): A Pooled Analysis. Polish Archives of Internal Medicine, 130(4), 304–309. https://doi.org/10.20452/pamw.15272
P2PTM Kemenkes RI. (2018). Lindungi Keluarga Dari Diabetes - Direktorat P2PTM. http://p2ptm.kemkes.go.id/post/lindungi-keluarga-dari-diabetes
P2PTM Kemenkes RI. (2019). Hari Hipertensi Dunia 2019 : "Know Your Number, Kendalikan Tekanan Darahmu dengan CERDIK.”. - Direktorat P2PTM. http://www.p2ptm.kemkes.go.id/kegiatan-p2ptm/pusat-/hari-hipertensi-dunia-2019-know-your-number-kendalikan-tekanan-darahmu-dengan-cerdik
Raden Muhammad Ali, S., Resty Varia, T., & Djazuly, C. (2020). Analisis Faktor Risiko Kematian dengan Penyakit Komorbid COVID-19. Jurnal Keperawatan Silampari, 4(1), 1689–1699.
Rozaliyani, A., Savitri, A. I., Setianingrum, F., Shelly, T. N., Ratnasari, V., Kuswindarti, R., Salama, N., Oktavia, D., Widyastuti, W., & Handayani, D. (2020). Factors Associated with Death in COVID-19 Patients in Jakarta, Indonesia: An Epidemiological Study. Acta Medica Indonesiana, 52(3), 246–254.
Satgas COVID-19. (2021). Peta Sebaran Satgas Penanganan COVID-19. https://covid19.go.id/peta-sebaran
Shah, P., Owens, J., Franklin, J., Mehta, A., Heymann, W., Sewell, W., Hill, J., Barfield, K., & Doshi, R. (2020). Demographics, Comorbidities and Outcomes in Hospitalized COVID-19 Patients in Rural Southwest Georgia. Annals of Medicine, 52(7), 1–7. https://doi.org/10.1080/07853890.2020.1791356
Shim, E., Mizumoto, K., Choi, W., & Chowell, G. (2020). Estimating the Risk of COVID-19 Death during theCourse of the Outbreak in Korea, February–May 2020. Journal of Clinical Medicine, 9, 1–9. https://doi.org/doi:10.3390/jcm9061641
Tian, S., Hu, N., Lou, J., Chen, K., Kang, X., Xiang, Z., Chen, H., Wang, D., Liu, N., Liu, D., Chen, G., Zhang, Y., Li, D., Li, J., Lian, H., Niu, S., Zhang, L., & Zhang, J. (2020). Characteristics of COVID-19 Infection in Beijing. Journal of Infection, 80(4), 401–406. https://doi.org/10.1016/j.jinf.2020.02.018
Wu, C., Chen, X., Cai, Y., Xia, J., Zhou, X., Xu, S., Huang, H., Zhang, L., Zhou, X., Du, C., Zhang, Y., Song, J., Wang, S., Chao, Y., Yang, Z., Xu, J., Zhou, X., Chen, D., Xiong, W., ... Song, Y. (2020). Risk Factors Associated with Acute Respiratory Distress Syndrome and Death in Patients with Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Internal Medicine, 180(7), 934–943. https://doi.org/10.1001/jamainternmed.2020.0994
Yan, Y., Yang, Y., Wang, F., Ren, H., Zhang, S., Shi, X., Yu, X., & Dong, K. (2020). Clinical Characteristics and Outcomes of Patients with Severe COVID-19 with Diabetes. BMJ Open Diabetes Research and Care, 8(1), 1–9. https://doi.org/10.1136/bmjdrc-2020-001343
Yang, Y., Zhong, W., Tian, Y., Xie, C., Fu, X., & Zhou, H. (2020). The Effect of Diabetes on Mortality of COVID-19: A Protocol for Systematic Review and Meta-Analysis. Medicine, 99(27), e20913. https://doi.org/10.1097/MD.0000000000020913
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