CONSTANT MURLEY SCORE ON PATIENTS POST SUPRASPINATUS RECONSTRUCTION WITH MEMBRANE AMNION COMPOSITE AND FAT TISSUE ALLOGENIC MESENCHYMAL STEM CELL AUGMENTATION
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Background: Rotator cuff tears are the most common cases in nontrauma upper extremities in group patient more than 50 years old. Incidence on rotator cuff can't show the real population. New Approaches healing rotator cuff syndrome is tendon regeneration like mesenchymal stem cell injection and growth factor or tissue engineering that has been developed.
Methods: Retrospective comparation study of 15 postsupraspinatus reparation patients who has been treated for more than 4 months at the Dr. Soetomo general hospital. Patients is divided into group undergone supraspinatus reparation and patient supraspinatus reparation with augmented by membrane amnion composite and mesenchymal stem cell. Its' functional results were evaluated using constant murley score.
Results: Pain score average on supraspinatus reparation patients which augmented by membrane amnion and mesenchymal stem cell and those without augmentation is 15 and 13.7 (p=0.036). Daily activity score average on patients with and without augmentation are 20 and 17 (p=0.037). Flexion score average on patients with and without augmentation are 10 and 8.6 (p=0.114). External rotation score average on patients with and without augmentation are 9.6 and 7.2 (p=0.004). Internal rotation score average on patients with and without augmentation are 9.2 and 7.2 (p=0.012).
Conclusion: The constant murley score pain score, ADL score, external rotation score, and internal rotation score in the group with the addition of amniotic membrane and mesenchymal stem cells were significantly better than the group with supraspinatus repair only, but not significantly on the flexion score and lateral elevation score components.Bianchi S, Martinoli C. Ultrasound of The Musculoskeletal System: Shoulder. 2007; Springer-Verlag 190e331.
M Precerutti, E Garioni, L Madonia, F Draghi. US Anatomy of the Shoulder: Pictorial Essay. Journal of Ultrasound. 2010; 13, 179e187.
Oliva F, Osti L, Padulo J, Maffulli N. Epidemiology of The Rotator Cuff Tears: A New Incidence Related to Thyroid Disease. Muscles Ligaments Tendons J. 2014;4(3):309–14. eCollection 2014.
Constant CR, Murley AHG. A Clinical Method of Functional Assessment of the Shoulder. Clin Orthop 1987; 214:160-4.
Yin B, Vella J, Levine WN. Arthroscopic Alphabet Soup: Recognition of Normal, Normal Variants, And Pathology. 2010; Orthop Clin North Am Jul;41(3):297e308.
Bishop J, Klepps S, Lo IK, Bird J, Gladstone JN, Flatow EL. Cuff Integrity After Arthroscopic Versus Open Rotator Cuff Repair: A Prospective Study. J Shoulder Elbow Surg. 2006; 15:290–9.
Galatz LM, Griggs S, Cameron BD, Iannotti JP. Prospective Longitudinal Analysis of Postoperative Shoulder Function: A Ten-Year Follow-Up Study of Full-Thickness Rotator Cuff Tears. J Bone Joint Surg Am. 2001; 83:1052–6.
Kim SH, Chung SW, Oh JH. Expression of Insulin-Like Growth Factor Type 1 Receptor and Myosin Heavy Chain in Rabbit's Rotator Cuff Muscle After Injection of Adipose-Derived Stem Cell. Knee Surg Sports Traumatol Arthrosc 2014;22(11):2867-73.
Plate JF, Brown PJ, Walters J, Clark JA, Smith TL, Freehill MT, et al. Advanced Age Diminishes Tendon-To-Bone Healing in A Rat Model of Rotator Cuff Repair. Am J Sports Med. 2014; 42:859–68.
Ilija Ban, Anders Troelsen, David Hí¸yrup Christiansen, Susanne Wulff Svendsen & Morten Tange Kristensen. Standardized Test Protocol (Constant Score) for Evaluation of Functionality in Patients with Shoulder Disorders. Dan Med J. 2013;60(4):A4608.
Pilar Tornero-Esteban, José Antonio Hoyas, Esther Villafuertes, Cruz Rodríguez-Bobada, Yamila López-Gordillo, Francisco J. Rojo, et al. Efficacy of Supraspinatus Tendon Repair Using Mesenchymal Stem Cells Along with A Collagen I Scaffold. Journal of Orthopaedic Surgery and Research. 2015;10:124.
Nourissat G, Diop A, Maurel N, Salvat C, Dumont S, Pigenet A, et al. Mesenchymal Stem Cell Therapy Regenerates the Native Bone-Tendon Junction After Surgical Repair in A Degenerative Rat Model. PLoS One. 2010;5:e12248.
Manning CN, Kim HM, Sakiyama-Elbert S, Galatz LM, Havlioglu N, Thomopoulos S. Sustained Delivery of Transforming Growth Factor Beta Three Enhances Tendon-To-Bone Healing in A Rat Model. J Orthop Res. 2011; 29:1099–105.
Santoni BG, McGilvray KC, Lyons AS, Bansal M, Turner AS, Macgillivray JD, et al. Biomechanical Analysis of an Ovine Rotator Cuff Repair Via Porous Patch Augmentation in A Chronic Rupture Model. Am J Sports Med. 2010; 38:679–86.
Yamamoto A, Takagishi K. The Impact of Faulty Posture on Rotator Cuff Tears with and without Symptoms. J Shoulder Elb Surg. 2014; 1-7.
Ariyando; I, Suroto H, Roeshadi D. Antara Ekspresi TGF-β pada Proses Penyembuhan Reparasi Ruptur Tendon Achilles dengan dan Tanpa Pemberian Sel Punca Mesensimal Sumsum Tulang. Journal Orthopaedi and Traumatology Surabaya. 2012;1(1):1-7.
Longo UG, Lamberti A, Petrillo S, Maffulli N, Denaro V. Scaffolds in Tendon Tissue Engineering. Stem Cells Int. 2012; 2012:517165.
Ellera Gomes JL, da Silva RC, Silla LM, Abreu MR, Pellanda R. Conventional Rotator Cuff Repair Complemented by The Aid of Mononuclear Autologous Stem Cells. Knee Surg Sports Traumatol Arthroscop 2012;20(2):373-7.
Isaac C, Gharaibeh B, Witt M, Wright VJ, Huard J. Biologic Approaches to Enhance Rotator Cuff Healing After Injury. J Shoulder Elb Surg. 2012; 21(2):181-190.
Joo Han Oh, Bong Jae Jun, Michelle H McGarry, Thay Q Lee. Surgery IS, Incorporated IN. Does A Critical Rotator Cuff Tear Stage Exist? 2011; 93a(22):2100-9.
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