Triple Local Recurrence of Synovial Sarcoma: A Case Report
Downloads
Background: Synovial Sarcoma (SS) hardly appears on non-extremity sites (20% of cases). Even rarer is a local recurrence, which occurs between 10-30% of cases. Here, we present a rare case of hip Synovial Sarcoma, which recurs three times.
Case Report: A 33-year-old male came to our outpatient clinic with chief complaints of a sudden ingrowing mass on his left hip. The lump is the size of a chicken egg and doesn't get bigger over time. There was palpable tenderness felt whenever he touched the lump. The patient was diagnosed with SS of the left hip with IIB stage from additional radiographic and histopathologic examination. Surgical-wide resection had been done three years before the visit, and chemotherapy six times. The lump reappeared one year before the visit, and the patient underwent a second surgery. The mass re-surfaced within the same region on the current visit for the third time, and he underwent the same surgical treatment afterward. Two years after the third surgery and adjuvant chemotherapy, the patient had no complaint about a lump and planned a radiograph evaluation.
Discussion: Detailed examination from history taking, physical examination, histopathologic, and radiological results is important to determine appropriate staging. With proper staging, physicians can better understand disease prognosis and risk of recurrence or metastases.
Conclusions: The third recurrence may still happen on SS. Its unique location might contribute to this unique occurrence, and the size of the tumor makes the recurrence rate higher.
Eilber FC and Dry SM. Diagnosis and management of synovial sarcoma. J Surg Oncol 2008;97(4):314–20.
Choi JH and Ro JY. The 2020 WHO Classification of Tumors of Soft Tissue: Selected Changes and New Entities. Adv Anat Pathol 2021;28(1):44-58.
Vodanovich DA and Choong PFM. Soft-tissue sarcomas. Indian J Orthop 2018;52(1):35–44.
Jo VY and Fletcher CDM. WHO classification of soft tissue tumours: An update based on the 2013 (4th) edition. Pathology 2014;46(2):95–104.
Aytekin MN, Öztürk R, Amer K, Yapar A. Epidemiology, incidence, and survival of synovial sarcoma subtypes: SEER database analysis. J Orthop Surg 2020;28(2): 2309499020936009.
Zhang H, Huang W, Feng Q, Sun W, Yan W, Wang C, et al. Clinical Significance and risk factors of local recurrence in synovial sarcoma: a retrospective analysis of 171 cases. Front Surg 2022;8:736146.
Faur CI, Pop DL, Awwad AA, Zamfir CL, Folescu R, Gurgus D, et al. Synovial sarcoma of the extremities: A literature review. Appl Sci (Switzerland) 2021;11(16):7407.
Fiore M, Sambri A, Spinnato P, Zucchini R, Giannini C, Caldari E, et al. The biology of synovial sarcoma: State-of-the-Art and Future Perspectives. Curr Treat Options Oncol 2021;22:109.
Kasraeian S, Allison DC, Ahlmann ER, Fedenko AN, Menendez LR. A comparison of fine-needle aspiration, core biopsy, and surgical biopsy in the diagnosis of extremity soft tissue masses. In: Clin Orthop Relat Res 2010;468(11):2992–3002.
Gazendam AM, Popovic S, Munir S, Parasu N, Wilson D, Ghert M. Synovial sarcoma: A clinical review. Curr Oncol 2021;28(3):1909–20.
Vlenterie M, Jones RL, van der Graaf WTA. Synovial sarcoma diagnosis and management in the era of targeted therapies. Curr Opin Oncol 2015;27(4):316–22.
Kartha SS and Bumpous JM. Synovial cell sarcoma: diagnosis, treatment, and outcomes. Laryngoscope 2002;112(11):1979-82.
Copyright (c) 2023 Journal Orthopaedi and Traumatology Surabaya
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
- The author acknowledges that the copyright of the article is transferred to the Journal of Orthopaedi and Traumatology Surabaya (JOINTS), whilst the author retains the moral right to the publication.
- The legal formal aspect of journal publication accessibility refers to Creative Commons Attribution-Non Commercial-Share Alike 4.0 International License (CC BY-NC-SA).
- All published manuscripts, whether in print or electronic form, are open access for educational, research, library purposes, and non-commercial uses. In addition to the aims mentioned above, the editorial board is not liable for any potential violations of copyright laws.
- The form to submit the manuscript's authenticity and copyright statement can be downloaded here.
Journal of Orthopaedi and Traumatology Surabaya (JOINTS) is licensed under a Creative Commons Attribution-Non Commercial-Share Alike 4.0 International License.