Correlation between salivary zinc levels and salivary volume on taste disorders in elderly patients
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Background: Taste disorders often occur in the elderly, which can have serious consequences on their health status. Zinc and saliva volume have a role in maintaining taste acuity, especially in the elderly. Purpose: This study was to determine the correlation between salivary zinc levels, salivary volume, and taste disorders in elderly patients. Methods: This was a cross-sectional research. Elderly patients with and without taste disorders were included in this study. Salivary zinc levels were measured using the Atomic Absorption Spectrometry (AAS) method. Salivary volume was measured using the spitting method. The correlation between salivary zinc levels, salivary volume, and taste disorders was analysed using the chi-square test. Multivariate analysis was performed to control for confounding variables with logistic regression. Results: Based on our findings, no significant correlation was determined between the levels of zinc in saliva and taste disorders. However, there was a significant correlation between salivary volume and taste disorders. Salivary volume and smoking were determined to be associated with taste disorders. Conclusion: This research showed that salivary zinc levels were not correlated with taste disorders; on the contrary, salivary volume was correlated with taste disorders. Smoking was determined to be a confounding variable on taste disorders in elderly patients.
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Pusat Data dan Informasi - Kementerian Kesehatan Republik Indonesia. Analisis Lansia di Indonesia. Buletin Kemenkes. 2017; : 1–10.
Razak PA, Richard KMJ, Thankachan RP, Hafiz KAA, Kumar KN, Sameer KM. Geriatric oral health: a review article. J Int oral Heal. 2014; 6(6): 110–6.
Amarya S, Singh K, Sabharwal M. Changes during aging and their association with malnutrition. J Clin Gerontol Geriatr. 2015; 6(3): 78–84.
Imoscopi A, Inelmen EM, Sergi G, Miotto F, Manzato E. Taste loss in the elderly: epidemiology, causes and consequences. Aging Clin Exp Res. 2012; 24(6): 570–9.
Aliani M, Udenigwe CC, Girgih AT, Pownall TL, Bugera JL, Eskin MNA. Zinc deficiency and taste perception in the elderly. Crit Rev Food Sci Nutr. 2013; 53(3): 245–50.
Watanabe M, Asatsuma M, Ikui A, Ikeda M, Yamada Y, Nomura S, Igarashi A. Measurements of several metallic elements and matrix metalloproteinases (MMPs) in saliva from patients with taste disorder. Chem Senses. 2005; 30(2): 121–5.
Ismawati R, Wirdjatmadi B, Yoes Priyatna D, Mertaniasih NM. The effect of zinc, lysine, and vitamin A supplementation to increase cellular immune response of pulmonary tuberculosis patients. Biochem Physiol Open Access. 2015; S5: 5–7.
Risso D, Drayna D, Morini G. Alteration, reduction and taste loss: Main causes and potential implications on dietary habits. Nutrients. 2020; 12(11): 3284.
Ambaldhage VK, Puttabuddi JH, Nunsavath PN, Tummuru YR. Taste disorders: A review. J Indian Acad Oral Med Radiol. 2014; 26(1): 69–76.
Kasuma N. Buku fisiologi dan patologi saliva. Padang: Andalas University Press; 2015. p. 1–26.
Aeran H, Seth J, Saxena S, Sharma G. Taste perception - A matter of sensation. Int J Oral Heal Dent. 2015; 1(2): 88–93.
Selow MLC, Lunelli F, Vieira I, Al E. Analysis of zinc concentration in the saliva of individuals at different age ranges. J Dent Sci. 2016; 31(1): 12–5.
Niklander S, Veas L, Barrera C, Fuentes F, Chiappini G, Marshall M. Risk factors, hyposalivation and impact of xerostomia on oral health-related quality of life. Braz Oral Res. 2017; 31: e14.
Villa A, Connell CL, Abati S. Diagnosis and management of xerostomia and hyposalivation. Ther Clin Risk Manag. 2014; 11: 45–51.
Takeuchi K, Furuta M, Takeshita T, Shibata Y, Shimazaki Y, Akifusa S, Ninomiya T, Kiyohara Y, Yamashita Y. Risk factors for reduced salivary flow rate in a Japanese population: The Hisayama study. Biomed Res Int. 2015; 2015: 1–7.
Pedersen AML, Sí¸rensen CE, Proctor GB, Carpenter GH, Ekström J. Salivary secretion in health and disease. J Oral Rehabil. 2018; 45(9): 730–46.
Sasano T, Satoh-Kuriwada S, Kaneta N, Shoji N, Kawai M, Uneyama H. Incidence of taste disorder and umami taste disorder among the Japanese elderly and youth. J Nutr Food Sci. 2012; S10: 1–4.
Hershkovich O, Nagler RM. Biochemical analysis of saliva and taste acuity evaluation in patients with burning mouth syndrome, xerostomia and/or gustatory disturbances. Arch Oral Biol. 2004; 49(7): 515–22.
Shatzman AR, Henkin RI. Gustin concentration changes relative to salivary zinc and taste in humans. Proc Natl Acad Sci USA. 1981; 78(6): 3867–71.
Pushpass RG, Daly B, Kelly C, Proctor G, Carpenter GH. Altered salivary flow, protein composition, and rheology following taste and TRP stimulation in older adults. Front Physiol. 2019; 10(652): 1–11.
Chéruel F, Jarlier M, Sancho-Garnier H. Effect of cigarette smoke on gustatory sensitivity, evaluation of the deficit and of the recovery time-course after smoking cessation. Tob Induc Dis. 2017; 15(1): 1–8.
Berkowitz L, Schultz BM, Salazar G, Pardo-Roa C, Sebastian VP, Alvarez-Lobos MM, Bueno SM. Impact of cigarette smoking on the gastrointestinal tract inflammation: Opposing effects in Crohn's disease and ulcerative colitis. Front Immunol. 2018; 9: 1–10.
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