Cleft lip and palate based on birth order and family history at Mitra Sejati General Hospital, Indonesia
Downloads
Background: Cleft lip and palate is one of the most common congenital abnormalities in infants and is caused by more than one factors, which can be genetic and environmental. Defects in a family gene can result in cleft lip and palate. The study found a high family history relationship with the incidence of cleft lip and palate. Birth order studied by several researchers also has different results, which were influenced by folic acid consumption, maternal knowledge, lack of antenatal care visits and maternal age. To determine the cases of cleft lip and palate based on the birth order of the children and family history of the patients at Mitra Sejati General Hospital. Purpose: The study aimed to investigate cleft lip and cleft palate patients by birth order and family history. Methods: This research was a retrospective descriptive study using survey method. Researchers gave 13 questions through a questionnaire and data were collected and counted manually. Results: The results showed that based on the birth, the cleft case in the first birth order amounted to 25 people, the second 30 people, the third 19 people, and the fourth or more as many as 20 people. Based on family history, 27 patients had a family history of cleft lip and palate, while 67 patients did not have family history. Conclusion: The cases of clefts at Mitra Sejati General Hospital happened more frequently in the second child and most incidence did not have family history.
Downloads
Ellis E. Management of patients with orofacial clefts. In: Hupp J, Tucker M, Ellis E, editors. Contemporary oral and maxillofacial surgery. 7th ed. Philadelphia: Mosby Elsevier; 2018. p. 608, 610, 615. web: https://www.elsevier.com/books/contemporary-oral-and-maxillofacial-surgery/hupp/978-0-323-55221-9
Martelli DRB, Coletta RD, Oliveira EA, Swerts MSO, Rodrigues LAM, Oliveira MC, Martelli Júnior H. Association between maternal smoking, gender, and cleft lip and palate. Braz J Otorhinolaryngol. 2015; 81(5): 514–9. doi: https://doi.org/10.1016/j.bjorl.2015.07.011
Salari N, Darvishi N, Heydari M, Bokaee S, Darvishi F, Mohammadi M. Global prevalence of cleft palate, cleft lip and cleft palate and lip: A comprehensive systematic review and meta-analysis. J Stomatol Oral Maxillofac Surg. 2022; 123(2): 110–20. doi: https://doi.org/10.1016/j.jormas.2021.05.008
Badan Penelitian dan Pengembangan Kesehatan. Riset kesehatan dasar 2013. Jakarta: Kemetrian Kesehatan Republik Indonesia; 2013. p. 188–9. web: https://www.litbang.kemkes.go.id/laporan-riset-kesehatan-dasar-riskesdas/
Badan Penelitian dan Pengembangan Kesehatan. Laporan Nasional Riskesdas 2018. Jakarta: Kementerian Kesehatan Republik Indonesia; 2018. p. 435. web: https://www.litbang.kemkes.go.id/laporan-riset-kesehatan-dasar-riskesdas/
Agbenorku P. Orofacial clefts: A worldwide review of the problem. ISRN Plast Surg. 2013; 2013: 1–7. doi: https://doi.org/10.5402/2013/348465
Jamilian A, Sarkarat F, Jafari M, Neshandar M, Amini E, Khosravi S, Ghassemi A. Family history and risk factors for cleft lip and palate patients and their associated anomalies. Stomatologija. 2017; 19(3): 78–83. pubmed: https://pubmed.ncbi.nlm.nih.gov/29339670/
Figueiredo RF, Figueiredo N, Feguri A, Bieski I, Mello R, Espinosa M, Damazo AS. The role of the folic acid to the prevention of orofacial cleft: an epidemiological study. Oral Dis. 2015; 21(2): 240–7. doi: https://doi.org/10.1111/odi.12256
Acuña-González G, Medina-Solís CE, Maupomé G, Escoffie-Ramírez M, Hernández-Romano J, Márquez-Corona M de L, Islas-Márquez AJ, Villalobos-Rodelo JJ. Family history and socioeconomic risk factors for non-syndromic cleft lip and palate: A matched case-control study in a less developed country. Biomedica. 2011; 31(3): 381–91. doi: https://doi.org/10.1590/S0120-41572011000300010
Noorollahian M, Nematy M, Dolatian A, Ghesmati H, Akhlaghi S, Khademi GR. Cleft lip and palate and related factors: A 10 years study in university hospitalised patients at Mashhad--Iran. Afr J Paediatr Surg. 2015; 12(4): 286–90. doi: https://doi.org/10.4103/0189-6725.172576
Jac-Okereke C, Onah I. Epidemiologic indices of cleft lip and palate as seen among Igbos in Enugu, Southeastern Nigeria. J Cleft Lip Palate Craniofacial Anomalies. 2017; 4(3): 126. doi: https://doi.org/10.4103/jclpca.jclpca_54_17
Kesande T, Muwazi LM, Bataringaya A, Rwenyonyi CM. Prevalence, pattern and perceptions of cleft lip and cleft palate among children born in two hospitals in Kisoro District, Uganda. BMC Oral Health. 2014; 14: 104. doi: https://doi.org/10.1186/1472-6831-14-104
Smile Train. RSU Mitra Sejati | Smile Train Indonesia. 2020. Available from: https://www.smiletrainindonesia.org/id/node/1618. Accessed 2021 Aug 3.
Triwardhani A, Permatasari G, Sjamsudin J. Variation of non-syndromic cleft lip/palate in yayasan Surabaya cleft lip/palate center Surabaya, Indonesia. J Int Oral Heal. 2019; 11(4): 187–90. doi: https://doi.org/10.4103/jioh.jioh_6_19
Hamamy H. Consanguineous marriages. J Community Genet. 2012; 3(3): 185–92. doi: https://doi.org/10.1007/s12687-011-0072-y
Küchler EC, Silva LA da, Nelson-Filho P, Sabóia TM, Rentschler AM, Granjeiro JM, Oliveira D, Tannure PN, Silva RA da, Antunes LS, Tsang M, Vieira AR. Assessing the association between hypoxia during craniofacial development and oral clefts. J Appl Oral Sci. 2018; 26: e20170234. doi: https://doi.org/10.1590/1678-7757-2017-0234
Suryandari AE. Hubungan antara umur ibu dengan klasifikasi labioschisis di RSUD Prof. Dr. Margono Soekarjo Purwokerto. Indones J Kebidanan. 2017; 1(1): 49–56. doi: https://doi.org/10.26751/ijb.v1i1.245
Pan X, Wang P, Yin X, Liu X, Li D, Li X, Wang Y, Li H, Yu Z. Association between maternal MTHFR polymorphisms and nonsyndromic cleft lip with or without cleft palate in offspring, A meta-analysis based on 15 case-control studies. Int J Fertil Steril. 2015; 8(4): 463–80. doi: https://doi.org/10.22074/ijfs.2015.4186
Wahl SE, Kennedy AE, Wyatt BH, Moore AD, Pridgen DE, Cherry AM, Mavila CB, Dickinson AJG. The role of folate metabolism in orofacial development and clefting. Dev Biol. 2015; 405(1): 108–22. doi: https://doi.org/10.1016/j.ydbio.2015.07.001
Hoshi R, Alves LM, Sá J, Peixoto Medrado A, De Castro Veiga P, de Almeida Reis SR. Nonsyndromic cleft lip and/or palate. The role of folic acid 30. Brazilian J Med Hum Heal. 2014; 2(1): 30–4. doi: https://doi.org/10.17267/2317-3386bjmhh.v2i1.357
Phyu MN, Lin Z, Tun K, Myint Wei T, Maung K. Maternal stressful events and socioeconomic status among orofacial cleft families: A hospital-based study. J Cleft Lip Palate Craniofacial Anomalies. 2020; 7(1): 24. doi: https://doi.org/10.4103/jclpca.jclpca_19_19
Suryani L, Rosyada A. The effect of unintended pregnancy among married women on the length of breastfeeding in Indonesia. J Ilmu Kesehat Masy. 2020; 11(2): 136–49. doi: https://doi.org/10.26553/jikm.2020.11.2.136-149
Coussons-Read ME. Effects of prenatal stress on pregnancy and human development: mechanisms and pathways. Obstet Med. 2013; 6(2): 52–7. doi: https://doi.org/10.1177/1753495X12473751
Kummet CM, Moreno LM, Wilcox AJ, Romitti PA, DeRoo LA, Munger RG, Lie RT, Wehby GL. Passive smoke exposure as a risk Factor for oral clefts-A large international population-based study. Am J Epidemiol. 2016; 183(9): 834–41. doi: https://doi.org/10.1093/aje/kwv279
Ozturk F, Sheldon E, Sharma J, Canturk KM, Otu HH, Nawshad A. Nicotine exposure during pregnancy results in persistent midline epithelial seam with improper palatal fusion. Nicotine Tob Res. 2016; 18(5): 604–12. doi: https://doi.org/10.1093/ntr/ntv227
Bui AH, Ayub A, Ahmed MK, Taioli E, Taub PJ. Maternal tobacco exposure and development of orofacial clefts in the child. Ann Plast Surg. 2018; 81(6): 708–14. doi: https://doi.org/10.1097/SAP.0000000000001665
Campos Neves A de S, Volpato LR, Espinosa M, Aranha AF, Borges A. Environmental factors related to the occurrence of oral clefts in a Brazilian subpopulation. Niger Med J. 2016; 57(3): 167. doi: https://doi.org/10.4103/0300-1652.184064
Lin Y, Shu S, Tang S. A case-control study of environmental exposures for nonsyndromic cleft of the lip and/or palate in eastern Guangdong, China. Int J Pediatr Otorhinolaryngol. 2014; 78(3): 545–51. doi: https://doi.org/10.1016/j.ijporl.2014.01.002
Moura E, Cirio SM, Pimpí£o CT. Nonsyndromic cleft lip and palate in boxer dogs: evidence of monogenic autosomal recessive inheritance. Cleft Palate Craniofac J. 2012; 49(6): 759–60. doi: https://doi.org/10.1597/11-110
Copyright (c) 2022 Dental Journal (Majalah Kedokteran Gigi)
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
- Every manuscript submitted to must observe the policy and terms set by the Dental Journal (Majalah Kedokteran Gigi).
- Publication rights to manuscript content published by the Dental Journal (Majalah Kedokteran Gigi) is owned by the journal with the consent and approval of the author(s) concerned.
- Full texts of electronically published manuscripts can be accessed free of charge and used according to the license shown below.
- The Dental Journal (Majalah Kedokteran Gigi) is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License