Cell phone radiation effect on osteocalcin and bone alkaline phosphatase
Downloads
Background: Electromagnetic fields are forces associated with moving electric charges and have electrical, magnetic components and contain electromagnetic energy, one of which is radio frequency (RF) energy which is commonly used in telecommunications. Cell phones are one of the RF electromagnetic radiation devices that can emit 90-2450 MHz waves and are often placed near the head. The human body works like an electromagnetic field in that each cell has its own electrical circuit characteristics. As the number of electromagnetic radiation devices in the environment increases, the electromagnetic balance in the human body may be disturbed by the magnetic waves produced by cell phones. Electromagnetic radiation is known to have the ability to induce oxidative stress, which is characterized by the accumulation of reactive oxygen species (ROS) in tissues. The accumulation of ROS in the body leads to osteoblast cell death. Osteoblasts are needed for mineralization of the extracellular matrix during bone growth. Therefore, bone growth is not optimal and can caused malocclusion. Purpose: This study aims to evaluate the relationship between electromagnetic radiation and osteocalcin and bone alkaline phosphatase (BALP) serum levels. Methods: Experimental laboratory research with a pre- and post-control group design approach was carried out on 12 Rattus norvegicus Wistar strain. Osteocalcin and BALP serum levels were calculated before and after treatment. This study used the t-test as a comparative study (p<0.05). Results: There are significant differences in osteocalcin and BALP values between the treatment groups before and after treatment. Conclusion: Cell phone radiations (electromagnetic field exposure) reduce osteocalcin and BALP serum levels.
Downloads
Lubis HF, Azriana A. Comparison of the Occlusal Feature Index (OFI) and Dental Aesthetic Index (DAI) in 10–14-year-old children at the Universitas Sumatera Utara Dental Hospital. Dent J. 2021; 54(4): 205–9. doi: https://doi.org/10.20473/j.djmkg.v54.i4.p205-209
Zou J, Meng M, Law CS, Rao Y, Zhou X. Common dental diseases in children and malocclusion. Int J Oral Sci. 2018; 10(1): 7. doi: https://doi.org/10.1038/s41368-018-0012-3
Jazaldi F, Soegiharto BM, Hutabarat AD, Soedarsono N, Auerkari EI. Runx2 rs59983488 polymorphism in class II malocclusion in the Indonesian subpopulation. Dent J. 2021; 54(4): 216–20. doi: https://doi.org/10.20473/j.djmkg.v54.i4.p216-220
Tallo FR, Narmada IB, Ardani IGAW. Maxillary anterior root resorption in Class II/I malocclusion patients post fixed orthodontic treatment. Dent J. 2020; 53(4): 201–5. doi: https://doi.org/10.20473/j.djmkg.v53.i4.p201-205
Lubis HF, Simanjuntak NU. The relationship between maxillary and mandibular lengths of ethnic Bataks of chronological age 9–15 years. Dent J. 2022; 55(2): 88–92. doi: https://doi.org/10.20473/j.djmkg.v55.i2.p88-92
Tanim MMZ. Electromagnetic radiation and human health. 2015. Available from: https://www.researchgate.net/publication/310426721_Electromagnetic_Radiation_and_Human_Health
Kumar V, Shah M, Kalra J, Pant B. Analytical study on the effects of electromagnetic waves on human beings. Int J Innov Technol Explor Eng. 2019; 8(4S3): 71–7. pdf: http://www.ijitee.org/wp-content/uploads/papers/v8i4s3/D10170384S319.pdf
Ishak NH, Ariffin R, Ali A, Meor Adzmey Sagiruddin, Mohamad Twon Tawi F. Biological effects of WiFi electromagnetic radiation. In: 2011 IEEE International Conference on Control System, Computing and Engineering. IEEE; 2011. p. 551–6. doi: https://doi.org/10.1109/ICCSCE.2011.6190587
Ambroszkiewicz J, Rowicka G, Chelchowska M, Gajewska J, StruciÅ„ska M, Laskowska-Klita T. Biochemical markers of bone metabolism in children with cow's milk allergy. Arch Med Sci. 2014; 6(6): 1135–41. doi: https://doi.org/10.5114/aoms.2013.36906
Houston BJ, Nixon B, King B V, De Iuliis GN, Aitken RJ. The effects of radiofrequency electromagnetic radiation on sperm function. Reproduction. 2016; 152(6): R263-76. doi: https://doi.org/10.1530/REP-16-0126
Yüksel M, Nazıroğlu M, Özkaya MO. Long-term exposure to electromagnetic radiation from mobile phones and Wi-Fi devices decreases plasma prolactin, progesterone, and estrogen levels but increases uterine oxidative stress in pregnant rats and their offspring. Endocrine. 2016; 52(2): 352–62. doi: https://doi.org/10.1007/s12020-015-0795-3
Adebayo EA, Adeeyo AO, Ogundiran MA, Olabisi O. Bio-physical effects of radiofrequency electromagnetic radiation (RF-EMR) on blood parameters, spermatozoa, liver, kidney and heart of albino rats. J King Saud Univ - Sci. 2019; 31(4): 813–21. doi: https://doi.org/10.1016/j.jksus.2018.11.007
Mashitoh Nur Iqlima. Kerusakan sel hepar akibat paparan radiasi elektromagnetik telepon seluler. Ibnu Sina J Kedokt dan Kesehat - Fak Kedokt Univ Islam Sumatera Utara. 2020; 19(1): 40–5. doi: https://doi.org/10.30743/ibnusina.v19i1.13
Bedir R, Tumkaya L, Mercantepe T, Yilmaz A. Pathological findings observed in the kidneys of postnatal male rats exposed to the 2100 MHz electromagnetic field. Arch Med Res. 2018; 49(7): 432–40. doi: https://doi.org/10.1016/j.arcmed.2018.12.010
AlmáÅ¡iová V, Holovská K, Cigánková V, RaÄeková E, Fabianová K, MartonÄíková M. Structural and ultrastructural study of rat testes influenced by electromagnetic radiation. J Toxicol Environ Heal Part A. 2014; 77(13): 747–50. doi: https://doi.org/10.1080/15287394.2014.890988
Kunt H, Senturk Ä°, Gonul Y, Korkmaz M, Ahsen A, Hazman Ö, Bal A, Genc A, Songur A. Effects of electromagnetic radiation exposure on bone mineral density, thyroid, and oxidative stress index in electrical workers. Onco Targets Ther. 2016; 9: 745–54. doi: https://doi.org/10.2147/OTT.S94374
Diyansah AB, Sulistyaningsih E, Hasan M. Pengaruh pemberian ekstrak etanol kakao (Theobroma cacao L.) terhadap kadar malondialdehida tikus Wistar jantan model fraktur tulang. Pustaka Kesehat. 2015; 3(1): 8–12. web: https://jurnal.unej.ac.id/index.php/JPK/article/view/2386
Ernawati DS, Nugraha AP, Narmada IB, Ardani IGAW, Hamid T, Triwardhani A, Winoto ER, Alida A, Susanto H, Ramadhani NF, Brahmanta A, Nugraha AP, Ihsan IS, Riawan W, Saskianti T, Noor TNE binti TA. The number of osteoblast and osteoclast during orthodontic tooth movement after preconditioned gingiva mesenchymal stem cell allogeneic transplantation in vivo. J Int Dent Med Res. 2022; 15(3): 1069–77. pdf: http://www.jidmr.com/journal/wp-content/uploads/2022/09/18-D22_1865_Alexander_Patera_Nugraha_Indonesia.pdf
Nugraha AP, Ernawati DS, Narmada IB, Bramantoro T, Riawan W, Situmorang PC, Nam HY. RANK-RANKL-OPG expression after gingival mesenchymal stem cell hypoxia preconditioned application in an orthodontic tooth movement animal model. J Oral Biol Craniofacial Res. 2023; 13(6): 781–90. doi: https://doi.org/10.1016/j.jobcr.2023.10.009
Halling Linder C, Ek-Rylander B, Krumpel M, Norgård M, Narisawa S, Millán JL, Andersson G, Magnusson P. Bone alkaline phosphatase and tartrate-resistant acid phosphatase: Potential co-regulators of bone mineralization. Calcif Tissue Int. 2017; 101(1): 92–101. doi: https://doi.org/10.1007/s00223-017-0259-2
Chen X, Wang Z, Duan N, Zhu G, Schwarz EM, Xie C. Osteoblast–osteoclast interactions. Connect Tissue Res. 2018; 59(2): 99–107. doi: https://doi.org/10.1080/03008207.2017.1290085
Copyright (c) 2024 Dental Journal
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
- Every manuscript submitted to must observe the policy and terms set by the Dental Journal (Majalah Kedokteran Gigi).
- Publication rights to manuscript content published by the Dental Journal (Majalah Kedokteran Gigi) is owned by the journal with the consent and approval of the author(s) concerned.
- Full texts of electronically published manuscripts can be accessed free of charge and used according to the license shown below.
- The Dental Journal (Majalah Kedokteran Gigi) is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License