Comparison of salivary alpha-amylase levels in gingivitis and periodontitis

Dyah Nindita Carolina, Yanti Rusyanti, Agus Susanto

= http://dx.doi.org/10.20473/j.djmkg.v50.i4.p216-219
Abstract views = 415 times | views = 184 times

Abstract


Background: The development of periodontal disease is influenced by bacteria-plaque, while there are also several factors modifying the host’s response, one of which is psychological stress. Alpha-amylase as a biomarker is also associated with periodontal inflammatory disease. Purpose: The purpose of this study was to examine the difference of alpha-amylase level between gingivitis and periodontitis. Methods: This research constitutes a descriptive study involving 44 subjects, divided into two groups: one of 22 gingivitis subjects and the other of 22 periodontitis subjects. These individuals completed a PSS-14 questionnaire before their levels of alpha salivary amylase were measured by Cocorometer. Data was analyzed by means of a paired T test and a Mann Whitney test with p < 0.05. Results: There were significant differences between the alpha-amylase levels of gingivitis and periodontitis. However, no significant contrast existed in the PSS-14 scores of the two periodontal disease groups. Conclusion: In conclusion alpha-amylase levels in the periodontitis group were higher than those in the gingivitis group and could be used as marker indicators of stress.

Keywords


alpha-amylase level; gingivitis; periodontitis; saliva; stress

Full Text:

PDF

References


Navalkar A, Bhoweer A. Alterations in whole saliva constituents in patients with diabetes mellitus and periodontal disease. J Indian Acad Oral Med Radiol. 2011; 23(4): 498–501.

Buduneli N, Özçaka Ö, Nalbantsoy A. Salivary and plasma levels of toll-like receptor 2 and toll-like receptor 4 in chronic periodontitis. J Periodontol. 2011; 82(6): 878–84.

Nater UM, Rohleder N, Schlotz W, Ehlert U, Kirschbaum C. Determinants of the diurnal course of salivary alpha-amylase. Psychoneuroendocrinology. 2007; 32(4): 392–401.

Baliga S, Muglikar S, Kale R. Salivary pH: a diagnostic biomarker. J Indian Soc Periodontol. 2013; 17(4): 461–5.

Sánchez GA, Miozza V, Delgado A, Busch L. Determination of salivary levels of mucin and amylase in chronic periodontitis patients. J Periodontal Res. 2011; 46(2): 221–7.

Mârţu S, Solomon S, Potârnichie O, Ărin LPĂS, Mârţu A, Nicolaiciuc O, Rescu IURSA. Evaluation of the prevalence of the periodontal disease versus systemic and local risk factors. Int J Med Dent. 2013; 3(3): 212–8.

Reis RS, Hino AAF, Añez CRR. Perceived stress scale: reliability and validity study in Brazil. J Health Psychol. 2010; 15(1): 107–14.

Pani SC, Al Askar AM, Al Mohrij SI, Al Ohali TA. Evaluation of stress in final-year Saudi dental students using salivary cortisol as a biomarker. J Dent Educ. 2011; 75(3): 377–84.

Akcali A, Huck O, Tenenbaum H, Davideau JL, Buduneli N. Periodontal diseases and stress: a brief review. J Oral Rehabil. 2013; 40(1): 60–8.

Bensley L, VanEenwyk J, Ossiander EM. Associations of selfreported periodontal disease with metabolic syndrome and number of self-reported chronic conditions. Prev Chronic Dis. 2011; 8(3): A50.

Tanaka Y, Ishitobi Y, Maruyama Y, Kawano A, Ando T, Okamoto S, Kanehisa M, Higuma H, Ninomiya T, Tsuru J, Hanada H, Kodama K, Isogawa K, Akiyoshi J. Salivary alpha-amylase and cortisol responsiveness following electrical stimulation stress in major depressive disorder patients. Prog Neuro-Psychopharmacology Biol Psychiatry. 2012; 36(2): 220–4.

Hinrichs JE, Novak MJ. Classification of diseases and conditions affecting the periodontium. In: Newman M, Takei H, Klokkevold P, Carranza F, editors. Carranza’s clinical periodontology. 11th ed. St. Louis: Saunders Elsevier; 2012. p. 34–55.

Reners M, Brecx M. Stress and periodontal disease. Int J Dent Hyg. 2007; 5(4): 199–204.

Papacosta E, Nassis GP. Saliva as a tool for monitoring steroid, peptide and immune markers in sport and exercise science. J Sci Med Sport. 2011; 14(5): 424–34.

Rohleder N, Nater UM. Determinants of salivaryα-amylase in humans and methodological considerations. Psychoneuroendocrinology. 2009; 34(4): 469–85.

Iacopino AM. Relationship between stress, depression and periodontal disease. J Can Dent Assoc (Tor). 2009; 75(5): 329–30.

Calvete E, Corral S, Estévez A. Cognitive and coping mechanisms in the interplay between intimate partner violence and depression. Anxiety, Stress & Coping. 2007; 20(4): 369–82.

Brouskeli V, Markos A. The role of locus of control and perceived stress in dealing with unemployment during economic crisis. Res Humanit Soc Sci. 2013; 3(21): 95–102.

Shende AS, Bhatsange AG, Waghmare AS, Shiggaon LB, Mehetre VN, Meshram EP. Determining the association between stress and periodontal disease: a pilot study. J Int Clin Dent Res Organ. 2016; 8(2): 111–4.

Rai B, Kaur J, Anand SC, Jacobs R. Salivary stress markers, stress, and periodontitis: a pilot study. J Periodontol. 2011; 82(2): 287–92.


Refbacks

  • There are currently no refbacks.


View My Stats