Ceramide is More Effective than Shea Butter in Maintaining Skin Acidity
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Background: Skin is the largest organ that functions as a physical barrier. Stable skin pH can maximize its function. Ceramide and shea butter cream have components that maintain the skin pH in the stratum corneum. Purpose: The aim is to compare ceramide and shea butter cream effects on skin pH. Methods: The experimental analytic study was performed on 30 respondents. The skin pH measurement was done before applying creams and 30 days after applying ceramide cream and shea butter cream. Ceramide cream was applied on the right volar and shea butter cream on the left volar. Comparative analysis with a paired t-test was used with a significant value of p<0.05. Results: The average skin pH after applying ceramide cream was 4,61±1,19, while shea butter cream was 5,30±1.07. The derivation of skin pH after ceramide cream application was 1,57±1,26, and that of shea butter cream was 0,88±1,14. The application of ceramide cream showed a lower pH than shea butter cream significantly, with p=0.025. Conclusion: The intervention using ceramide and shea butter cream for 30 days could lower the skin pH level. The derivation of skin pH with ceramide is more significant than using shea butter cream. Ceramide can be considered to maintain skin homeostasis and skin pH.
Elias PM. The how, why and clinical importance of stratum corneum acidification. Exp Dermatol. 2017 Nov; 26(11): 999-1003.
í‰vora AS, Adams MJ, Johnson SA, Zhang Z. Corneocytes: relationship between structural and biomechanical properties. Skin Pharmacol Physiol. 2021 Mar 29; 34(2): 1-6.
Diociaiuti A, Martinelli D, Nicita F, Cesario C, Pisaneschi E, Macchiaiolo M, Rossi S, Condorelli AG, Zambruno G, El Hachem M. Two Italian patients with elovl4-related neuro-ichthyosis: expanding the genotypic and phenotypic spectrum and ultrastructural characterization. Genes. 2021 Mar; 12(3): 343.
Purnamawati S, Indrastuti N, Danarti R, Saefudin T. The role of moisturizers in addressing various kinds of dermatitis: a review. Clin Med Res. 2017 Dec 1; 15(3-4): 75-87.
Choi EH. Aging of the skin barrier. Clin Dermatol. 2019 Jul-Aug; 37(4): 336-345.
Phuong C, Maibach HI. Gender differences in skin. Textbook of Aging Skin. 2016: 1729-55.
Cha HJ, He C, Zhao H, Dong Y, An IS, An S. Intercellular and intracellular functions of ceramides and their metabolites in skin. Int J Mol Med. 2016 Jul 1; 38(1): 16-22.
Oh MJ, Cho YH, Cha SY, Lee EO, Kim JW, Kim SK, Park CS. Novel phytoceramides containing fatty acids of diverse chain lengths are better than a single C18-ceramide N-stearoyl phytosphingosine to improve the physiological properties of human stratum corneum. Clin Cosmet and Investig Dermatol. 2017; 10: 363.
Lin TK, Zhong L, Santiago JL. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int J Mol Sci. 2018 Jan; 19(1): 70.
Maanikuu J, Peker A. Medicinal and nutritional benefits from the Shea tree (Vitellaria paradoxa). J Biol Agric Healthc. 2017; 7(22): 51-8.
Maranduca MA, Branisteanu D, Serban DN, Branisteanu DC, Stoleriu G, Manolache N, Serban IL. Synthesis and physiological implications of melanic pigments. Oncol Lett. 2019 May 1; 17(5): 4183-7.
Kilic A, Masur C, Reich H, Knie U, Dähnhardt D, Dähnhardt"Pfeiffer S, Abels C. Skin acidification with a water in oil emulsion (pH 4) restores disrupted epidermal barrier and improves structure of lipid lamellae in the elderly. J Dermatol. 2019 Jun; 46(6): 457-65.
Jung D, Jin Y, Kang S, Lee H, Park K, Li K, Kim JH, Geum JH, Lee J. An HPLC-UV-based quantitative analytical method for Chrysanthemum morifolium: development, validation, and application. Anal Sci Technol. 2019; 32(4): 139-46.
Sirignano C, Nadembega P, Poli F, Romano B, Lucariello G, Rigano D, Taglialatela-Scafati O. Triterpenoids from Vitellaria paradoxa Stem Barks Reduce Nitrite Levels in LPS-Stimulated Macrophages. Plants. 2021 May; 10(5): 1006.
Drakou K, Tsianni A, Vrani F, Kefala V, Rallis
E. Revealing the Correlation between Altered Skin Lipids Composition and Skin Disorders. Cosmetics. 2021; 8(3): 88.
Kahraman E, Kaykın M, Åžahin Bektay H, Güngör S. Recent advances on topical application of ceramides to restore barrier function of skin. Cosmetics. 2019 Sep; 6(3): 52.
Lueangarun S. The 24-hr, 28-day, and 7-day post-moisturizing efficacy of ceramides 1, 3, 6-II containing moisturizing cream compared with hydrophilic cream on skin dryness and barrier disruption in senile xerosis treatment. Dermatol Ther. 2019 Nov; 32(6): 1–7.
Turner N, Lim XY, Toop HD, Osborne B, Brandon AE, Taylor EN, et al. A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism. Nat Commun. 2018; 9(3165): 1-14.
Lim D, Bae S, Oh T. Anti-inflammatory effect of shea butter extracts in canine keratinocytes. J Vet Clin. 2021; 38(1): 27–31.
Draelos ZD. A pilot study investigating the efficacy of botanical anti-inflammatory agents in an OTC eczema therapy. J Cosmet Dermatol. 2016 Jun; 15(2): 117–9.
Raffin RP, Lima A, Lorenzoni R, Antonow MB, Turra C, Alves MP, et al. Natural lipid nanoparticles containing nimesulide: synthesis, characterization, and in vivo antiedematogenic and antinociceptive activities. J Biomed Nanotechnol. 2012; 8(2): 309–15.
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