The Effects of Hormonal Factor on the Degree of Acne Vulgaris Severity
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Background: Acne vulgaris is a disease in the form of chronic inflammation of the pilosebaceous follicles with multifactorial causes. Acne vulgaris is a very common skin disease with a prevalence of 85% in the age range of 18-25 years. There are aggravating factors that can exacerbate acne vulgaris, including hormonal factors. However, the study about how strong the effects of hormonal factors and on acne severity is really limited. Purpose: The objective of this research is to determine how strong hormonal factors contribute on the severity of acne vulgaris. Methods: This was a cross-sectional retrospective study using secondary data obtained from 199 patients at the Dermatology and Venereology Outpatient Unit of RSUD Dr. Soetomo from January- December 2019. The data were analyzed using SPSS with regression analysis.Result: Hormonal factors significantly influenced the degree of acne vulgaris severity (P-value=0.030). Based on the logistic regression model, it can be found that hormonal factors influence the degree of acne vulgaris by 70% Conclusion: The effect of hormonal factors on the severity of acne vulgaris is 70%.
Sihotang IBS, Wasitatmadja SM. Akne Vulgaris. In: Ilmu Penyakit Kulit dan Kelamin. 7th ed. Jakarta: Badan Penerbit FKUI; 2016. p. 288.
Goh C, Cheng C, Agak G, Zaenglein AL, Graber EM, Thiboutot DM, et al. Acne Vulgaris. In: Fitzpatrick's Dermatology. 9th ed. New York: McGraw-Hill Education; 2019. p. 1391.
Mayslich C, Grange PA, Dupin N. Cutibacterium acnes as an Opportunistic Pathogen: An Update of Its Virulence-Associated Factors. Microorganisms [Internet]. 2021 Feb 2;9(2):303.
Dawson AL, Dellavalle RP. Acne vulgaris. BMJ. 2013 May 8;346(may08 1):f2634–f2634.
Sutaria AH, Masood S SJ. Acne Vulgaris [Internet]. Treasure Island (FL): StatPearls Publishing; 2021.
Chuah S, Goh C. The impact of post-acne scars on the quality of life among young adults in Singapore. J Cutan Aesthet Surg [Internet]. 2015;8(3):153.
Hazarika N, Archana M. The psychosocial impact of acne vulgaris. Indian J Dermatol. 2016;61(5):515.
Henshaw E, Ogedegbe E. Severity and impact of acne vulgaris on the quality of life of adolescents in Nigeria. Clin Cosmet Investig Dermatol. 2014 Dec;329.
Tasoula E, Gregoriou S, Chalikias J, Lazarou D, Danopoulou I, Katsambas A, et al. The impact of acne vulgaris on quality of life and psychic health in young adolescents in Greece: results of a population survey. An Bras Dermatol. 2012 Dec;87(6):862–9.
Indramaya DM, Manuputty AG, Eva L, Rahmadewi R, Umborowati MA, Widiatma RR, et al. Kualitas Hidup Pasien Dewasa Muda dengan Akne Vulgaris Derajat Sedang di Indonesia. Berkala Ilmu Kesehatan Kulit Dan Kelamin. 2019 Dec;31.
Elsaie M. Hormonal treatment of acne vulgaris: an update. Clin Cosmet Investig Dermatol. 2016 Sep;Volume 9:241–8.
Elsaie M. Hormonal treatment of acne vulgaris: an update. Clin Cosmet Investig Dermatol. 2016 Sep;Volume 9:241–8.
Lucky AW. Quantitative Documentation of a Premenstrual Flare of Facial Acne in Adult Women. Arch Dermatol. 2004 Apr 1;140(4).
Howland MA, Donzella B, Miller BS, Gunnar MR. Pubertal recalibration of cortisol-DHEA coupling in previously-institutionalized children. Horm Behav. 2020 Sep;125:104816.
Lynn D, Umari T, Dellavalle R, Dunnick C. The epidemiology of acne vulgaris in late adolescence. Adolesc Health Med Ther. 2016 Jan;13.
. Lynn D, Umari T, Dellavalle R, Dunnick C. The epidemiology of acne vulgaris in late adolescence. Adolesc Health Med Ther. 2016 Jan;13.
Bhate K, Williams HC. Epidemiology of acne vulgaris. British Journal of Dermatology. 2013 Mar;168(3):474–85.
Srinivasan B, Premkumar S. Assessment of serum dehydroepiandrosterone sulphate in subjects during the pre-pubertal, pubertal, and adult stages of skeletal maturation. The European Journal of Orthodontics. 2012 Aug 1;34(4):447–51.
Matulevicius V. Importance of Dehydroepiandrosterone Sulfate Assessment with Special Attention for Adrenal Tumours and Arterial Hypertension. Acta Endocrinologica (Bucharest). 2021;17(1):68–76.
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