Article Sidebar

Submitted
2 October 2019
Accepted
2 October 2019
Published
3 October 2019
Download
PDF
Statistic
Read Counter : 1130 Download : 1196

Main Article Content

Abstract

Every year, there are 500.000 new cases and more than 250.000 deaths caused by cervical cancerworldwide. Cervical cancer patients faced physical and psychological problems several times that it activate stress mechanism such as hypothalamus-pituitary-adrenal (HPA) axis. These recurrent activations caused HPA axis disruption and adverse clinical effects. Several symptoms of endocrine stress response are the change of circadian cortisol rhythm. Cortisol is known as a stress hormone that involves an organism's response to stress and anxiety that influence the quality of life. This research aims to analyze the differences among serum cortisol level, anxiety, and quality of life in cervical cancer patients before and after psychocurative intervention in obstetrics and gynecology wards and polyclinic in RSUD Dr. Moewardi Surakarta. This research is an experimental double-blind randomized controlled clinical trial pre-test post-test group design study. The subjects were advance stage (IIB-IV)cervical cancer patients. The subjects were randomly chosen into fifteen subjects that given standard therapy and psychocurative, while the other fifteen subjects as a control only got standard therapy. Data were obtained from measurement of serum cortisol level, anxiety questionnaire DASS 42 and WHO quality of life questionnaire. Data were analyzed using SPSS 21 using difference test. The difference mean test result of cortisol serum level, anxiety, quality of life from the controlled group and uncontrolled group showed a significant difference (p < 0.05). In conclusion, psychocurative is significant to reduce cortisol level, anxiety, and improve the quality of life in advanced stage cervical cancer patients.

Keywords

Psychocurative cortisol anxiety quality of life

Article Details

License

  • Folia Medica Indonesiana is a scientific peer-reviewed article which freely available to be accessed, downloaded, and used for research purposes. Folia Medica Indonesiana (p-ISSN: 2541-1012; e-ISSN: 2528-2018) is licensed under a Creative Commons Attribution 4.0 International License. Manuscripts submitted to Folia Medica Indonesiana are published under the terms of the Creative Commons License. The terms of the license are:

    Attribution ” You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

    NonCommercial ” You may not use the material for commercial purposes.

    ShareAlike ” If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.

    No additional restrictions ” You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

    You  are free to :

    Share ” copy and redistribute the material in any medium or format.

    Adapt ” remix, transform, and build upon the material.

How to Cite
Soetrisno, S., Mulyani, S., Nurinasari, H., Nurinasari, H., & Budi, E. (2019). The Influence of Psychocurative on Cortisol Level, Anxiety, and Quality of Life in Advanced Stage Cervical Cancer Patients. Folia Medica Indonesiana, 55(3), 202–205. https://doi.org/10.20473/fmi.v55i3.15502
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. in cervical cancer survivors. Acta Medica Marisiensis 58, 275-277
  2. American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorder. 5th Ed. Virginia, American Psychiatric Publishing, p 155-158
  3. Andrijono (2007). Kanker serviks. Jakarta, Balai Penerbit Fakultas Kedokteran Universitas Indonesia
  4. Azis MF (2009). Gynecological cancer in Indonesia, J Gynecol Oncol 20, 8-10
  5. Bastaman HD (2007). Logoterapi: Psikologi untuk menemukan makna hidup dan meraih hidup bermakna. 1st Ed. Jakarta, PT Raja Grafindo Persada
  6. Himpunan Onkologi Ginekologi Indonesia (2013). Panduan pelayanan klinik kanker ginekologi. Jakarta, Himpunan Onkologi Ginekologi Indonesia
  7. Kang KA, Im JI, Kim HS, et al (2009). The effect of logotherapy on the suffering,finding meaning, and spiritual well-being of adolescents with terminal cancer. JKorean Acad Child Health Nus 15, 136-144
  8. King CR, Hinds PS (2012). Quality of life: From nursing and patient perspectives. United Kingdom, Jones and Barlett Publishers
  9. Lovallo WR, Farag NH, Vincent AS, et el (2006). Cortisol responses to mental stres, exercise, and meals following caffeine intake in men and women. Pharmacology Biochemistry and Be-haviour 83, 441-447
  10. Martha M (2006). Effect of spirituality in breast cancer survivors. Oncology Nursing Forum 33, E1-E7
  11. Murti B (2010). Desain dan ukuran sampel untuk penelitian kuantitatif dan kualitatif di bidang kesehatan. Yogyakarta, Gajah Mada University Press
  12. Rasjidi I (2009). Epidemiologi kanker serviks. Indonesian Journal of Cancer 3, 108
  13. Schettler T (2013). The ecology of breast cancer: The promise of preventionand the hope for healing. Stres, Social Support, and Breast Cancer, 145-162
  14. Sephton SE, Sapolsky RM, Kraemer HC, et al (2000). Diurnal cortisol rhythm as a predictor of breast cancer survival. J Natl Cancer Inst. 92, 994-1000.
  15. Stone AA, Schwartz JE, Smyth J, et al (2001). Individual differences in the diurnal cycle of salivary free cortisol: A replication of flattened cycles for some individuals. Psychoneuroendocrinology 26, 295-306
  16. Soetrisno (2009). Ekspresi Heat shock Protein60,70,90 dan kortisol pada persalinan ibu primigravida yang mendapat psikokuratif. A dissertation. Surabaya, Universitas Airlangga
  17. Young AH (2004). Cortisol in mood disorders. Stress 7, 205-8