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Submitted
13 January 2021
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13 January 2021
Published
30 June 2019
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Abstract

The phenomena of increasing total IgE level in Soil Transmitted Helminthiasis and its protective role in resistance of infection remains unclear. The purpose of this study was to determine the correlation between total IgE and the intensity of Soil transmitted helminthiasis among farmers in these area. Total 162 farmer, age ranged 25-80 years participated in this cross sectional analytic study. Kato-Katz method was used to diagnose Soil Transmitted Helminthiasis and to determined infection intensity based on egg per gram (EPG). Total IgE levels were measured by enzyme linked flourescent assay (ELFA). The results of this study showed that 13,56% farmer positive  for Soil Transmitted Helminthiasis, with single infection of Ascaris lumbricoides were 1,85%, 9,26% for Trichuris trichiura, 0,61% for Hookworm and mixed infection that were 1,23% for A.lumbricoides+T.trichiura 0,61%  for A.lumbricoides+Hookworm. The intensity of infection were in mild category. Total IgE level in Soil transmitted Helminthiasis group was significantly different compared with noninfected group (p<0.05, t-test). There was significant correlation between EPG and total IgE level (r=0.667, p=0.001, Spearman test). As a conclusion total IgE level was significantly correlated with EPG, this fact can be used to develop management of Soil Transmitted Helminthiasis theraphy.

Keywords

Farmers soil transmitted helminthiasis total IgE level EPG Klungkung Bali

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How to Cite
Apsari, P. I. B., Arwati, H., & Dachlan, Y. P. (2019). Correlation of Total IgE Level and Intensity of Infection among Soil Transmitted Helminthiasis Farmers in Klungkung Regency, Bali, Indonesia. Folia Medica Indonesiana, 55(2), 93–99. https://doi.org/10.20473/fmi.v55i2.24562
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References

  1. Acevedo N, Erler A, Briza P (2011). Allergenicity of Ascaris lumbricoides tropomyosin and IgE sensitization among asthmatic patients in a tropical environment. Int Arch Allergy Immunol 154, 195-206
  2. Amoah ID, Abubakari A, Stenstrom TA (2016). Contribution of wastewater irrigation to soil transmitted helminths infection among vegetable farmers in Kumasi, Ghana. PLOS Neglected Tropical Diseases 10, 1-12
  3. Andereck JW, Kipp, Aaron M, Ondieck M, Vermund SH (2014). Helminth prevalence among adult in rural Kenya: a stool survey for soil-transmitted helminth and Schistosomiasis in Nyanza province. Transaction of the Royal Society of Tropical Medicine and Hygiene 108, 804-806
  4. Anthony RM, Rutitzky LI, Urban JF (2007). Protective immune mechanisms in helminth infection. Nature Publishing Group 7, 975-987
  5. Bethony J, Brooker S, Albonico M (2006). Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet 367, 1521–1532
  6. Cooper PJ (2009). Interaction between helminth parasite and allergy. Curr Opin allergy Clin Immunol 9, 29-37
  7. Cooper PJ, Ayre G, Martin C (2008). Geohelminth infections: a review of the role of IgE and assessment of potential risks of anti-IgE treatment. Allergy 63, 409-417
  8. Elfred, Arwati H, Suwarno (2016). Gambaran basofil, TNF-a, dan IL-9 pada petani terinfeksi STH di kabupaten Kediri. Jurnal Biosains Pascasarjana 18, 1-13
  9. Ensink JH, Hoek Wvd, Mukhtarb M (2005). High risk of Hookworm infection among wastewater farmers in Pakistan. Transactions of the Royal Society of Tropical Medicine and Hygiene 99, 809-811
  10. Farrar J, Hotez PJ, Junghanss T (2014). Manson's Tropical Disease. 23rd ed. China, Elsevier
  11. Gabrie JA, et al (2016). Immune profile of Honduran schoolchildren with intestinal parasites: The Skewed response against geohelminths. Journal of Parasitology Research, 1-13
  12. Geiger SM, Alexander, NDE, Fujiwara RT, Brooker S (2011). Necator americanus and helminth co-infection: Further down-modulation of hookworm-specific type 1 immune responses. Plos Neglected Tropical Disease 5, 1-11
  13. Pham-Duc P, Nguyen-Viet H, Hattendorf J (2013). Ascaris lumbricoides and Trichuris trichiura infections associated with wastewater and human excreta use in agriculture in Vietnam. Parasitology International 62, 172-180
  14. Smits HH, Everts B, Hartgers FC, Yazdanbakhsh M (2010). Chronic helminth infections protect against allergic diseases by active regulatory processes. Curr Allergy Asthma Rep 10, 3-12
  15. Sudarmaja I (2011). Epidemologi infeksi kecacingan di Bali. Bali, Laboratorium Parasitologi, Universitas Udayana
  16. WHO (1991). Basic laboratory method in medical parasitology. 1st Ed. Geneva, World Health Organzation
  17. WHO (2017). World Health Organization. www.who.int/intestinal_worms. Accessed August 16, 2017
  18. Wijaya H, Irsa L, Loebis S (2014). Total serum IgE levels in soil transmitted helminth infected children with atopy symptoms. Paediatrica Indonesiana 54, 149-153