Main Article Content


Chondrosarcoma is a rare variant of bladder tumor and one of the rare types of soft tissue sarcoma. This case happened on a 36-year-old male who complained of lumps in his lower abdomen, accompanied by difficulties in passing urine and painful urination, without hematuria. We performed TURBT and histopathological examination showed low-grade chondrosarcoma. The patient was diagnosed with low-grade bladder chondrosarcoma. The patient was treated for chemotherapy and radiotherapy. However, after undergoing one cycle of chemotherapy, the patient refused to continue the therapy.

Article Details

How to Cite
Tamrin, M. H., & Djatisoesanto, W. (2021). Bladder Chondrosarcoma in A Male: A Rare Case Report. Folia Medica Indonesiana, 57(3), 256–261.


  1. American Cancer Society (2014). Soft tissue sarcoma causes, risk factors, and prevention. Available from Accessed March 13, 2021.
  2. Baskar R, Lee KA, Yeo R, et al (2012). Cancer and radiation therapy: Current advances and future directions. International Journal of Medical Sciences 9, 193-199.
  3. Casali PG, Blay JY (2010). Soft tissue sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Annals of Oncology 21, 198-203.
  4. Cho MH, Kim SH, Park WS, et al (2016). Bladder chondrosarcoma plus urothelial carcinoma in recurred transitional cell carcinoma of the upper urinary tract: A case report and literature review. World Journal of Surgical Oncology 14, 1-4.
  5. Gupta SR, Saran RK, Sharma P, et al (2015). A rare case of extraskeletal mesenchymal chondrosarcoma with dedifferentiation arising from the buccal space in a young male. Journal of Maxillofacial and Oral Surgery 14, 293-299.
  6. He Z, Sha N, Qi S-Y, et al (2016). Primary chondrosarcoma of the prostate: A case report. International Journal of Clinical and Experimental Pathology 9, 2512-2515.
  7. Ikemoto S, Sugimura K, Yoshida N, et al (2004). Chondrosarcoma of the urinary bladder and establishment of a human chondrosarcoma cell line (OCUU-6). Human Cell 17, 93-96.
  8. Kim M-J, Cho K-J, Ayala AG, et al (2011). Chondrosarcoma: With updates on molecular genetics. Sarcoma 2011, 1-16.
  9. Miyake M, Nishimura N, Inoue T, et al (2021). Fluorescent cystoscopy-assisted en bloc transurethral resection versus conventional transurethral resection in patients with non-muscle invasive bladder cancer: study protocol of a prospective, open-label, randomized control trial (the FLEBER study). Trials 22, 1-10.
  10. Petsko GA (2011). NCCN clinical practice guidelines in oncology (NCCN GuidelinesTM) soft tissue sarcoma version 1.2011. Genome Biology 8, 1-82.
  11. Richterstetter M, Wullich B, Amann K, et al (2012). The value of extended transurethral resection of bladder tumour (TURBT) in the treatment of bladder cancer. BJU Int 110, E76-E79.
  12. Sule N, Xu B, Zein DE, et al (2015). Radiation-induced chondrosarcoma of the bladder. Case report and review of literature. Anticancer Research 35, 2857-2860.
  13. von Mehren M, Randall RL, Benjamin RS, et al (2016). Soft Tissue sarcoma, version 2.2016, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw 14, 758-86.
  14. Yoon SM, Chu F-I, Ruan D, et al (2021). Assessment of toxic effects associated with dose-fractionated radiotherapy among patients with cancer and comorbid collagen vascular disease. JAMA Netw Open 4, 1-14.
  15. Zieschang H, Koch R, Wirth MP, et al (2019). Leiomyosarcoma of the urinary bladder in adult patients: A systematic review of the literature and meta-analysis. Urol Int 102, 96-101.
  16. Zulfariska N, Martadiani ED, Wiratnaya IGE, et al (2020). Variasi kondrosarkoma pada usia muda: Serial kasus. MEDICINA 51, 567-570.