Main Article Content
Abstract
Highlights:
1. Although dermatophytes may typically cause mild infections, it is crucial to conduct continuous research due to their potential to cause severe diseases in individuals who are highly susceptible to infection.
2. This study offers insight into the increased risk of developing dermatophytosis for female and adult individuals compared to male and younger individuals.
Abstract
Dermatophytosis is a superficial fungal infection caused by a filamentous fungus that attacks keratinized tissues on the skin, nails, and hair. The clinical manifestation of dermatophytosis is determined by the source. In addition, it can be influenced by host-related factors, such as age, sex, and race. These are significant epidemiological factors, although the association between these factors and susceptibility to infection has not been clarified. Therefore, this study aimed to determine the association between the incidence of dermatophytosis and host-related factors (i.e., age and sex) in Gianyar Regency, Indonesia. This observational study used a cross-sectional design and total sampling. A total of 100 samples were collected from the medical records of patients diagnosed with dermatophytosis. The Chi-square test was employed to determine the correlation between the independent and dependent variables with a p-value of <0.05. The data were analyzed using IBM SPSS Statistics for Windows, version 22.0 (IBM Corp., Armonk, N.Y., USA). The majority of patients with dermatophytes infection were adults over the age of 19 (74%) and females (57%). The most prevalent type of dermatophytosis was tinea corporis (36%). The Chi-square test revealed a significant association between the type of dermatophytosis and the variables being examined, namely age (p = 0.025; OR = 1.978; 95% CI = 1.087-3.599) and sex (p = 0.003; OR = 2.357; 95% CI = 1.334-4.162). In conclusion, the manifestation of certain types of dermatophytosis is associated with age and sex. The findings of this study recommend enhancing the detection of dermatophytosis infection, especially in adults (>19 years old) and women.
Keywords
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References
- Akbas A, Kilinc F, Yakut I, et al (2016). Superficial fungal infections in children. Medical Science and Discovery 3, 280. doi: 10.17546/msd.77042.
- Al-Janabi AAH, Al-Khikani FHO (2020). Dermatophytoses: A short definition, patho genesis, and treatment. International Journal of Health & Allied Sciences 9, 210. doi: 10.4103 /ijhas.IJHAS_123_19.
- Anggarini DR, Sukanto H, Astari L, et al (2015). Susceptibility test of griseofulvin, ketoconazole, itraconazole, and terbinafine to dermatophyte species using microdilution method. BIKKK - Berkala Ilmu Kesehatan Kulit dan Kelamin - Periodical of Dermatology and Venereology 27, 55–62. Available at: https://e-journal.unair.ac.id/ BIKK/article/download/1553/1201.
- Araya S, Abuye M, Negesso AE (2021). Epidemiological characterization of dermato mycosis in Ethiopia. Clinical, Cosmetic and Investigational Dermatology 14, 83–89. doi: 10.2147/CCID.S292286.
- Aref S, Nouri S, Moravvej H, et al (2022). Epidemiology of dermatophytosis in Tehran, Iran: A ten-year retrospective study. Archives of Iranian Medicine 25, 502-507. doi: 10.34172/aim. 2022.82.
- Astrid CP (2016). Characteristics of dermato phytosis in Haji Adam Malik General Hospital, period of January 1st 2015 to December 31st 2015 (thesis). Universitas Sumatera Utara. Available at: https://repositori.usu.ac.id/handle/123456789/22080.
- Bitew A (2018). Dermatophytosis: Prevalence of dermatophytes and non-dermatophyte fungi from patients attending arsho advanced medical Laboratory, Addis Ababa, Ethiopia. Dermatology Research and Practice 2018, 1–6. doi: 10.1155/20 18/8164757.
- Bitew A, Wolde S (2019). Prevalence, risk factors, and spectrum of fungi in patients with onychomycosis in Addis Ababa, Ethiopia: A prospective study. Journal of Tropical Medicine 2019, 1–6. doi: 10.1155/2019/3652634.
- Clebak KT, Malone MA (2018). Skin infections. Primary Care: Clinics in Office Practice 45, 433–454. doi: 10.1016/j.pop.2018.05.004.
- Cornelissen CN, Hobbs MM (2020). Lippincott® illustrated reviews: Microbiology (Lippincott illustrated reviews series), 4th edn. Wolters Kluwer, Philadelphia. Available at: https://www. amazon.com/Lippincott-Illustrated-Reviews-Micr obiology/dp/1496395859?asin=1496395859&revisionId=&format=4&depth=1.
- Devy D, Ervianti E (2018). Characteristic of dermatophytosis: A retrospective study. BIKKK - Berkala Ilmu Kesehatan Kulit dan Kelamin - Periodical of Dermatology and Venereology 30, 66–72. Available at: https://e-journal.unair.ac.id/B IKK/article/view/4573.
- Ely JW, Rosenfeld S, Seabury Stone M (2014). Diagnosis and management of tinea infections. American Family Physician 90, 702–710. Available at: http://www.ncbi.nlm.nih.gov/pubme d/25403034.
- Errichetti E, Stinco G (2018). Dermoscopy in tinea manuum. Anais Brasileiros de Dermatologia 93, 447–448. doi: 10.1590/abd1806-4841.20186366.
- IBM Corp (2013). IBM SPSS Statistics for Windows, Version 22.0. Armonk, NY: IBM Corp. Availanle at: https://www.ibm.com/id-id/products /spss-statistics.
- Jartarkar SR, Patil A, Goldust Y, et al (2021). Pathogenesis, immunology and management of dermatophytosis. Journal of Fungi 8, 39. doi: 10.3390/jof8010039.
- Kang S, Amagai M, Bruckner AL, et al (2019). Fitzpatrick's dermatology, ninth edition. McGraw-Hill Education, USA. Available at: https://www.amazon.com/Fitzpatricks-Dermatolo gy-Ninth-General-Medicine/dp/0071837795?asin =0071837795&revisionId=&format=4&depth=1.
- Kovitwanichkanont T, Chong A (2019). Superficial fungal infections. Australian Journal of General Practice 48, 706–711. doi: 10.31128/AJGP-05-19-4930.
- Marsaoly RR, Hari ED, Ariwangsa G, et al. (2014). Profile of superficial dermatomycosis in geriatrical patients at Polyclinic of Dermatology and Venerology RSUP Sanglah Denpasar Bali on 2010-2014 period. Fakultas Kedokteran Universitas Udayana. Available at: https://simdos. unud.ac.id/uploads/file_penelitian_1_dir/f9438201850a02a937e942e156a9b6bc.pdf.
- Noegroho TA, Rosmelia, Nabila LM (2017). The prevalence of dermatological infection in outpatient dermatology clinic of RSUD Wonosari in January-September 2016. Jurnal Kedokteran dan Kesehatan Indonesia 8, 96–101. doi: 10.20885 /JKKI.Vol8.Iss2.art4.
- Noronha T, Tophakhane R, Nadiger S (2016). Clinico-microbiological study of dermatophytosis in a tertiary-care hospital in North Karnataka. Indian Dermatology Online Journal 7, 264. doi: 10.4103/2229-5178.185488.
- Petrucelli MF, Abreu MH de, Cantelli BAM, et al (2020). Epidemiology and diagnostic perspectives of dermatophytoses. Journal of Fungi 6, 310. doi: 10.3390/jof6040310.
- Rashidian S, Falahati M, Kordbacheh P, et al. (2015). A study on etiologic agents and clinical manifestations of dermatophytosis in Yazd, Iran. Current Medical Mycology 1, 20–25. doi: 10.18869/acadpub.cmm.1.4.20.
- Sari KESSP (2021). Profile of dermatophytos in Mycology division Outpatient Clinic Sanglah General Hospital Bali in2017 and 2018 periods. Medika Udayana 10, 99–104. doi: 10.24843.MU. 2021.V10.i4.P016.
- Singhal R, Rana R (2015). Chi-square test and its application in hypothesis testing. Journal of the Practice of Cardiovascular Sciences 1, 69. doi: 10.4103/2395-5414.157577.
- Sondakh CEEJ, Pandaleke TA, Mawu FO (2016). Profile of dermatophytosis at the Dermato venerology Clinic of Prof. Dr. R. D. Kandou Hospital Manado during the period of January-December 2013. e-CliniC. doi: 10.35790/ ecl.v4i1.12134.
- Talari K, Goyal M (2020). Retrospective studies – Utility and caveats. Journal of the Royal College of Physicians of Edinburgh 50, 398–402. doi: 10.4997/jrcpe.2020.409.
- Taufiq, Batubara DE (2020). Profile of dermatophytosis at Deli Serdang Regional General Hospital 2015-2017. Jurnal Ilmiah Maksitek 5, 32–39. Available at: https://makarioz.sciencemaka rioz.org/index.php/JIM/article/view/205/196.
- Vassar M, Matthew H (2013). The retrospective chart review: important methodological considerations. Journal of Educational Evaluation for Health Professions 10, 12. doi: 10.3352/jeehp. 2013.10.12.
- Vishnu S, Tarun KK, Anima S, et al. (2015). Dermatophytes: Diagnosis of dermatophytosis and its treatment. African Journal of Microbiology Research 9, 1286–1293. doi: 10.5897/AJMR2015. 7374.
- Wang X, Ding C, Xu Y, et al. (2020). Analysis on the pathogenic fungi in patients with superficial mycosis in the Northeastern China during 10 years. Experimental and Therapeutic Medicine 20, 1. doi: 10.3892/etm.2020.9411.
- World Health Organization (2022). Countries urged to adapt strategic framework to address huge un met needs of skin diseases. WHO. Available at: https://www.who.int/news/item/13-06-2022-coun tries-urged-to-adapt-strategic-framework-to-addre ss-huge-unmet-needs-of-skin-diseases.
- Yuwita W, Ramali LM, Miliawati R (2016). Characteristic of tinea cruris and/or tinea corporis in Ciamis District Hospital, West Java. BIKKK - Berkala Ilmu Kesehatan Kulit dan Kelamin - Periodical of Dermatology and Venereology 28, 42–51. Available at: https://e-journal.unair.ac.id/B IKK/article/view/2815/2034.
References
Akbas A, Kilinc F, Yakut I, et al (2016). Superficial fungal infections in children. Medical Science and Discovery 3, 280. doi: 10.17546/msd.77042.
Al-Janabi AAH, Al-Khikani FHO (2020). Dermatophytoses: A short definition, patho genesis, and treatment. International Journal of Health & Allied Sciences 9, 210. doi: 10.4103 /ijhas.IJHAS_123_19.
Anggarini DR, Sukanto H, Astari L, et al (2015). Susceptibility test of griseofulvin, ketoconazole, itraconazole, and terbinafine to dermatophyte species using microdilution method. BIKKK - Berkala Ilmu Kesehatan Kulit dan Kelamin - Periodical of Dermatology and Venereology 27, 55–62. Available at: https://e-journal.unair.ac.id/ BIKK/article/download/1553/1201.
Araya S, Abuye M, Negesso AE (2021). Epidemiological characterization of dermato mycosis in Ethiopia. Clinical, Cosmetic and Investigational Dermatology 14, 83–89. doi: 10.2147/CCID.S292286.
Aref S, Nouri S, Moravvej H, et al (2022). Epidemiology of dermatophytosis in Tehran, Iran: A ten-year retrospective study. Archives of Iranian Medicine 25, 502-507. doi: 10.34172/aim. 2022.82.
Astrid CP (2016). Characteristics of dermato phytosis in Haji Adam Malik General Hospital, period of January 1st 2015 to December 31st 2015 (thesis). Universitas Sumatera Utara. Available at: https://repositori.usu.ac.id/handle/123456789/22080.
Bitew A (2018). Dermatophytosis: Prevalence of dermatophytes and non-dermatophyte fungi from patients attending arsho advanced medical Laboratory, Addis Ababa, Ethiopia. Dermatology Research and Practice 2018, 1–6. doi: 10.1155/20 18/8164757.
Bitew A, Wolde S (2019). Prevalence, risk factors, and spectrum of fungi in patients with onychomycosis in Addis Ababa, Ethiopia: A prospective study. Journal of Tropical Medicine 2019, 1–6. doi: 10.1155/2019/3652634.
Clebak KT, Malone MA (2018). Skin infections. Primary Care: Clinics in Office Practice 45, 433–454. doi: 10.1016/j.pop.2018.05.004.
Cornelissen CN, Hobbs MM (2020). Lippincott® illustrated reviews: Microbiology (Lippincott illustrated reviews series), 4th edn. Wolters Kluwer, Philadelphia. Available at: https://www. amazon.com/Lippincott-Illustrated-Reviews-Micr obiology/dp/1496395859?asin=1496395859&revisionId=&format=4&depth=1.
Devy D, Ervianti E (2018). Characteristic of dermatophytosis: A retrospective study. BIKKK - Berkala Ilmu Kesehatan Kulit dan Kelamin - Periodical of Dermatology and Venereology 30, 66–72. Available at: https://e-journal.unair.ac.id/B IKK/article/view/4573.
Ely JW, Rosenfeld S, Seabury Stone M (2014). Diagnosis and management of tinea infections. American Family Physician 90, 702–710. Available at: http://www.ncbi.nlm.nih.gov/pubme d/25403034.
Errichetti E, Stinco G (2018). Dermoscopy in tinea manuum. Anais Brasileiros de Dermatologia 93, 447–448. doi: 10.1590/abd1806-4841.20186366.
IBM Corp (2013). IBM SPSS Statistics for Windows, Version 22.0. Armonk, NY: IBM Corp. Availanle at: https://www.ibm.com/id-id/products /spss-statistics.
Jartarkar SR, Patil A, Goldust Y, et al (2021). Pathogenesis, immunology and management of dermatophytosis. Journal of Fungi 8, 39. doi: 10.3390/jof8010039.
Kang S, Amagai M, Bruckner AL, et al (2019). Fitzpatrick's dermatology, ninth edition. McGraw-Hill Education, USA. Available at: https://www.amazon.com/Fitzpatricks-Dermatolo gy-Ninth-General-Medicine/dp/0071837795?asin =0071837795&revisionId=&format=4&depth=1.
Kovitwanichkanont T, Chong A (2019). Superficial fungal infections. Australian Journal of General Practice 48, 706–711. doi: 10.31128/AJGP-05-19-4930.
Marsaoly RR, Hari ED, Ariwangsa G, et al. (2014). Profile of superficial dermatomycosis in geriatrical patients at Polyclinic of Dermatology and Venerology RSUP Sanglah Denpasar Bali on 2010-2014 period. Fakultas Kedokteran Universitas Udayana. Available at: https://simdos. unud.ac.id/uploads/file_penelitian_1_dir/f9438201850a02a937e942e156a9b6bc.pdf.
Noegroho TA, Rosmelia, Nabila LM (2017). The prevalence of dermatological infection in outpatient dermatology clinic of RSUD Wonosari in January-September 2016. Jurnal Kedokteran dan Kesehatan Indonesia 8, 96–101. doi: 10.20885 /JKKI.Vol8.Iss2.art4.
Noronha T, Tophakhane R, Nadiger S (2016). Clinico-microbiological study of dermatophytosis in a tertiary-care hospital in North Karnataka. Indian Dermatology Online Journal 7, 264. doi: 10.4103/2229-5178.185488.
Petrucelli MF, Abreu MH de, Cantelli BAM, et al (2020). Epidemiology and diagnostic perspectives of dermatophytoses. Journal of Fungi 6, 310. doi: 10.3390/jof6040310.
Rashidian S, Falahati M, Kordbacheh P, et al. (2015). A study on etiologic agents and clinical manifestations of dermatophytosis in Yazd, Iran. Current Medical Mycology 1, 20–25. doi: 10.18869/acadpub.cmm.1.4.20.
Sari KESSP (2021). Profile of dermatophytos in Mycology division Outpatient Clinic Sanglah General Hospital Bali in2017 and 2018 periods. Medika Udayana 10, 99–104. doi: 10.24843.MU. 2021.V10.i4.P016.
Singhal R, Rana R (2015). Chi-square test and its application in hypothesis testing. Journal of the Practice of Cardiovascular Sciences 1, 69. doi: 10.4103/2395-5414.157577.
Sondakh CEEJ, Pandaleke TA, Mawu FO (2016). Profile of dermatophytosis at the Dermato venerology Clinic of Prof. Dr. R. D. Kandou Hospital Manado during the period of January-December 2013. e-CliniC. doi: 10.35790/ ecl.v4i1.12134.
Talari K, Goyal M (2020). Retrospective studies – Utility and caveats. Journal of the Royal College of Physicians of Edinburgh 50, 398–402. doi: 10.4997/jrcpe.2020.409.
Taufiq, Batubara DE (2020). Profile of dermatophytosis at Deli Serdang Regional General Hospital 2015-2017. Jurnal Ilmiah Maksitek 5, 32–39. Available at: https://makarioz.sciencemaka rioz.org/index.php/JIM/article/view/205/196.
Vassar M, Matthew H (2013). The retrospective chart review: important methodological considerations. Journal of Educational Evaluation for Health Professions 10, 12. doi: 10.3352/jeehp. 2013.10.12.
Vishnu S, Tarun KK, Anima S, et al. (2015). Dermatophytes: Diagnosis of dermatophytosis and its treatment. African Journal of Microbiology Research 9, 1286–1293. doi: 10.5897/AJMR2015. 7374.
Wang X, Ding C, Xu Y, et al. (2020). Analysis on the pathogenic fungi in patients with superficial mycosis in the Northeastern China during 10 years. Experimental and Therapeutic Medicine 20, 1. doi: 10.3892/etm.2020.9411.
World Health Organization (2022). Countries urged to adapt strategic framework to address huge un met needs of skin diseases. WHO. Available at: https://www.who.int/news/item/13-06-2022-coun tries-urged-to-adapt-strategic-framework-to-addre ss-huge-unmet-needs-of-skin-diseases.
Yuwita W, Ramali LM, Miliawati R (2016). Characteristic of tinea cruris and/or tinea corporis in Ciamis District Hospital, West Java. BIKKK - Berkala Ilmu Kesehatan Kulit dan Kelamin - Periodical of Dermatology and Venereology 28, 42–51. Available at: https://e-journal.unair.ac.id/B IKK/article/view/2815/2034.