Dewi Nurul Mustaqimah

Abstract views = 858 times | downloads = 449 times


The etiology of polymicrobial disease such as periodontitis is likely to be more complex than suggested by the traditional paradigm of disease involving a single virulent organism which up to now has been believed. This review limits its discussion to the other subgingival microbiota which is not yet cultivable, however it is suggested be implicated with the severity of periodontal disease. The intricate interactions between viruses and bacteria within periodontal pockets as a co-infection process reveal its role in the etio-pathogenesis of periodontal disease. Also Archaea domain participate in syntrophic relationship with the microbiota life members in the subgingival crevice, promote colonization by special bacterial group during periodontitis. It is clear that periodontal diseases are not monoinfections.


polymicrobial disease; co-infection process; syntrophic relationship; severe periodontal disease; etio-pathogenesis mechanism

Full Text:



  • There are currently no refbacks.

Copyright (c) 2016 Indonesian Journal of Tropical and Infectious Disease

View My Stats

IJTID Indexed by : 


IJTID (pISSN 2085-1103eISSN 2356-0991is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Lembaga Penyakit Tropis (Institute of Tropical Disease)

Universitas Airlangga

Kampus C Mulyorejo

Surabaya 60115