High Toxoplasmosis Seroprevalence and Anemia Among Early-Mid Pregnant Women in Jember, Indonesia
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Toxoplasmosis is an infection caused by the parasite Toxoplasma gondii, which can be transmitted through various routes. Toxoplasmosis in pregnant women may cause abortion and fetal disabilities. Decreased body immunity due to anemia can increase the risk of toxoplasmosis during pregnancy. The purpose of this study was to identify the characteristics of pregnant women and their association with anemia, determine the prevalence of anemia and toxoplasmosis infection in pregnant women, and investigate whether anemia is a risk factor for toxoplasmosis in pregnant women. This research is an analytical, observational study using a cross-sectional laboratory examination. The sample in this study consisted of blood collected from first- and second-trimester pregnant women at the Kaliwates and Banjarsengon Public Health Centers for hemoglobin analysis and toxoplasmosis serology. Accidental sampling was conducted from July to December 2024. The research data were presented in tabular form and analyzed using the Chi-square test. This study was conducted on 65 pregnant women. The number of pregnant women with anemia was 43% and the number of pregnant women who were positive for toxoplasmosis was 66%. A significant association exists between gestational age and anemia (p-value = 0,041). Bivariate analysis between anemia and T. gondii infection showed no significant association (p-value = 0.182). This study concludes that anemia is not proven to be a risk factor for toxoplasmosis infection in pregnant women. However, the cases of anemia and toxoplasmosis were high and require specific attention.
Deganich M, Boudreaux C, Benmerzouga I. Toxoplasmosis Infection during Pregnancy. Trop Med Infect Dis [Internet]. 2023 Jan 1 [cited 2024 Jul 4];8(1). DOI: 10.3390/tropicalmed8010003
Rostami A, Riahi SM, Gamble HR, Fakhri Y, Nourollahpour Shiadeh M, Danesh M, et al. Global prevalence of latent toxoplasmosis in pregnant women: a systematic review and meta-analysis. Clin Microbiol Infect [Internet]. 2020 Jun 1 [cited 2024 Sep 18];26(6):673–83. DOI : 10.1016/j.cmi.2020.01.008
Polanunu NFA, Wahyuni S, Hamid F. Seroprevalence and associated risk factors of Toxoplasma gondii infection among pregnant mother in Makassar, Indonesia. PLoS One [Internet]. 2021;16(6 June):1–10. DOI: 10.1371/journal.pone.0245572.
Korespondensi A, Sembiring K, Lubis B, Rosdiana N, Nafianti S, Siregar OR. Status Imunitas Anak dengan Anemia Defisiensi Besi [Immunological Profile of Children with Iron Deficiency Anemia]. [Internet]. Available from: https://cdkjournal.com/index.php/CDK/article/view/719
Sana M, Rashid M, Rashid I, Akbar H, Gomez-Marin JE, Dimier-Poisson I. Immune response against toxoplasmosis—some recent updates RH: Toxoplasma gondii immune response. Int J Immunopathol Pharmacol [Internet]. 2022 [cited 2024 Sep 14];36:1–19. DOI : 10.1177/03946320221078436
Jember District Health Office. Health Profile of Jember Regency 2023. Jember: Jember District Health Office; 2023.https://dinkes.jemberkab.go.id/posts/profil-kesehatan-kabupaten-jember-tahun-2023
Vueba AN, Faria CP, Almendr R, Santan P, Do Ceu Sousa M. Serological prevalence of toxoplasmosis in pregnant women in Luanda (Angola): Geospatial distribution and its association with socio-demographic and clinical-obstetric determinants. PLoS One [Internet]. 2020 Nov 1 [cited 2024 Oct 24];15(11):e0241908. DOI : 10.1371/journal.pone.0241908
Dumilah R. Umur, Interval Kehamilan, Kehamilan yang Diinginkan dan Perilaku Pemeriksaan Kehamilan [Maternal Age, Interpregnancy Interval, Pregnancy Intention, and Antenatal Care-Seeking Behavior]. J Penelit Kesehat Suara Forikes. 2019;10(2):73–9. https://forikes-ejournal.com/index.php/SF/article/view/377
Dewi HP, Mardiana M. Faktor Risiko Yang Mempengaruhi Kejadian Anemia Pada Ibu Hamil Di Wilayah Kerja Puskesmas Nusawungu Ii Cilacap [Determinants of Anemia among Pregnant Women in the Nusawungu II Health Center Area, Cilacap]. J Nutr Coll. 2021;10(4):285–96. DOI: 10.14710/jnc.v10i4.31642
Zhang J, Li Q, Song Y, Fang L, Huang L, Sun Y. Nutritional factors for anemia in pregnancy: A systematic review with meta-analysis. Front Public Heal [Internet]. 2022 Oct 14 [cited 2024 Nov 24];10:1041136. DOI : 10.3389/fpubh.2022.1041136
Isnaini YS, Yuliaprida R, Pihahey PJ. Hubungan Usia, Paritas Dan Peker Hubungan Usia, Paritas Dan Pekerjaan Terhadap Kejadian Anemia Pada Ibu Hamil [Association of Age, Parity, and Occupation with Anemia Among Pregnant Women]. Nurs Arts. 2021;15(2):65–74. https://jurnal.poltekkes-sorong.id/index.php/NA/article/view/39
Amini A, Pamungkas CE, Harahap APHP. Usia Ibu Dan Paritas Sebagai Faktor Risiko Yang Mempengaruhi Kejadian Anemia Pada Ibu Hamil Di Wilayah Kerja Puskesmas Ampenan [Maternal Age and Parity as Risk Factors Influencing the Incidence of Anemia in Pregnant Women in the Working Area of Ampenan Public Health Center]. Midwifery J J Kebidanan UM Mataram. 2018;3(2):108. DOI : 10.31764/mj.v3i2.506
Harna H, Muliani EY, Sa’pang M, Dewanti LP, Irawan AMA. Prevalensi dan Determinan Kejadian Anemia Ibu Hamil [Prevalence and Determinant of Anemia Pregnant Women]. Jik J Ilmu Kesehat. 2020;4(2):78. DOI : 10.33757/jik.v4i2.289
Mustafa KM, Mohammed AB, Mero WMS. Seroprevalence of Toxoplasma gondii Antibodies and Associated Risk Factors Among Women in Zakho City, Iraq. Cureus. 2024;16(3). DOI: 10.7759/cureus.56328
Teimouri A, Mohtasebi S, Kazemirad E, Keshavarz H. Role of Toxoplasma gondii IgG Avidity Testing in Discriminating between Acute and Chronic Toxoplasmosis in Pregnancy. J Clin Microbiol [Internet]. 2020 Sep 1 [cited 2024 Nov 7];58(9):e00505-20. DOI : 10.1128/jcm.00505-20
J.L. Ndamukong-nyanga, N. Jacqueline, D. Flavia, N.C. Ndamukong DNN. Facteurs socio-démographiques et attitudes influençant la séroprévalence de la toxoplasmose chez les femmes enceintes à Buea, Sw Cameroun. J sud-asiatique Parasitol. 2020;3. https://journalsajp.com/index.php/SAJP/article/view/42
Johnson HJ, Koshy AA. Latent Toxoplasmosis Effects on Rodents and Humans: How Much is Real and How Much is Media Hype? MBio [Internet]. 2020 Mar 1 [cited 2024 Nov 14];11(2). DOI: 10.1128/mbio.02164-19
Nadia NAC, Nino LG, Cédric Y, Raoul SNS, Christian NO, Esther DD, et al. Seroprevalence of Toxoplasma gondii IgG and IgM antibodies and associated risk factors among pregnant women consulted in three health centers in Dschang, Cameroon. Parasite Epidemiol Control. 2023 Aug 1;22:e00306. DOI : 10.1016/j.parepi.2023.e00306
Bieńkowski C, Aniszewska M, Kowalczyk M, Popielska J, Zawadka K, Ołdakowska A, et al. Analysis of Preventable Risk Factors for Toxoplasma gondii Infection in Pregnant Women: Case-Control Study. J Clin Med [Internet]. 2022 Feb 1 [cited 2024 Nov 24];11(4):1105. DOI: 10.3390/jcm11041105
Rahmanian V, Rahmanian K, Jahromi AS, Bokaie S. Seroprevalence of toxoplasma gondii infection: An umbrella review of updated systematic reviews and meta-analyses. J Fam Med Prim Care [Internet]. 2020 [cited 2024 Nov 21];9(8):3848. DOI: 10.4103/jfmpc.jfmpc_753_20
Konstantinovic N, Guegan H, Stäjner T, Belaz S, Robert-Gangneux F. Treatment of toxoplasmosis: Current options and future perspectives. Food Waterborne Parasitol. 2019 Jun 1;15:e00036. DOI : 10.1016/j.fawpar.2019.e00036
Mitterstiller AM, von Raffay L, Nairz M. Iron Deficiency, Anemia, and the Immune System. 2022 [cited 2024 Nov 21];235–48. Available from: https://link.springer.com/chapter/10.1007/978-3-031-14521-6_18
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