The difference between residual monomer dentin bonding HEMA and UDMA with acetone and ethanol solvent after binding to type I collagen

N. Normayanti, Adioro Soetojo, Nirawati Pribadi

Abstract views = 80 times | views = 39 times


Background: In caries and non-caries lesions involving dentine, it is necessary to provide dentine-bonding material to help improve retention between the composite resin and the tooth surface. Composite resin attachment to dentine is influenced by bonding polymerization reactions. In several studies, researchers found that polymerized monomers will experience volume shrinkage because not all will fully polymerize but, rather, become residual monomers that can cause post-operative pain. Purpose: This study aimed to identify the difference in the amount of residual monomers between HEMA- and UDMA-based dentin bonding materials with acetone and ethanol solvents after binding to type I collagen. Methods: Four groups featured in this study: HEMA with acetone solvent and type I collagen , HEMA with ethanol solvent and type I collagen , UDMA with acetone solvent and type I collagen and UDMA with ethanol solvent and type I collagen . All groups were checked by high performance liquid chromatography (HPLC) to quantify the remaining amount of monomers. Results: The percentage of residual monomers of dentine bonding HEMA with acetone solvent and type I collagen was 10.69%, HEMA with ethanol solvent and type I collagen was 13.93%, UDMA with acetone solvent and type I collagen was 2.89% and UDMA with ethanol solvent and type I collagen was 7.48%. Conclusion: HEMA with ethanol solvent has the highest number of residual monomers, while UDMA with acetone solvent has the lowest.


acetone; ethanol; HEMA; residual monomer; UDMA

Full Text:



Anusavice KJ, Phillips RW, Shen C, Rawls HR. Phillips’ science of dental materials. 12th ed. St Louis Missouri: Saunders; 2012. p. 176-258.

Soetojo A. Penggunaan resin komposit dalam bidang konservasi gigi. Surabaya: Revka Petra Media; 2013. p. 23-112.

Sogata OP, Lunardhi CGJ, Subiwahjudi A. Perbedaan kebocoran mikro pada restorasi tumpatan dengan bonding berbasis HEMA dan Non-HEMA. Conserv Dent J. 2016; 6: 45–50.

Ekambaram M, Yiu CKY, Matinlinna JP. An overview of solvents in resin-dentin bonding. Int J Adhes Adhes. 2015; 57: 22–33.

Botsali MS, Kuşgöz A, Altintaş SH, Ülker HE, Tanriver M, Kiliç S, Başak F, Ülker M. Residual HEMA and TEGDMA release and cytotoxicity evaluation of resin-modified glass ionomer cement and compomers cured with different light sources. Sci World J. 2014; 2014: 1–7.

Altunsoy M, Botsali MS, Tosun G, Yasar A. Effect of increased exposure times on amount of residual monomer released from single-step self-etch adhesives. J Appl Biomater Funct Mater. 2015; 13(3): e287–92.

Charasseangpaisarn T, Wiwatwarrapan C, Leklerssiriwong N. Ultrasonic cleaning reduces the residual monomer in acrylic resins. J Dent Sci. 2016; 11(4): 443–8.

Hargreaves KM, Berman LH, Rotstein I. Cohen’s pathways of the pulp. 11th ed. St. Louis: Mosby Elsevier; 2015. p. 411-54.

Ubaldini ALM, Baesso ML, Sehn E, Sato F, Benetti AR, Pascotto RC. Fourier transform infrared photoacoustic spectroscopy study of physicochemical interaction between human dentin and etch-&-rinse adhesives in a simulated moist bond technique. J Biomed Opt. 2012; 17(6): 1–5.

Van Landuyt KL, Snauwaert J, De Munck J, Peumans M, Yoshida Y, Poitevin A, Coutinho E, Suzuki K, Lambrechts P, Van Meerbeek B. Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials. 2007; 28(26): 3757–85.

Bakir Ş, Bakir EP, Yildirim ZS. Biocompatibility of dental adhesives. Adv Dent Oral Heal. 2017; 4(4): 1–6.

Moreira F do CL, Antoniosi Filho NR, de Souza JB, Lopes LG. Sorption, solubility and residual monomers of a dental adhesive cured by different light-curing units. Braz Dent J. 2010; 21(5): 432–8.

Papakonstantinou AE, Eliades T, Cellesi F, Watts DC, Silikas N. Evaluation of UDMA’s potential as a substitute for Bis-GMA in orthodontic adhesives. Dent Mater. 2013; 29(8): 898–905.

Koliniotou-Koumpia E, Kouros P, Koumpia E, Helvatzoglou-Antoniades M. Shear bond strength of a “solvent-free” adhesive versus contemporary adhesive systems. Braz J Oral Sci. 2014; 13: 64–9.

Silva E Souza MH, Carneiro KGK, Lobato MF, Silva E Souza PDAR, de Góes MF. Adhesive systems: important aspects related to their composition and clinical use. J Appl Oral Sci. 2010; 18(3): 207–14.


  • There are currently no refbacks.

View My Stats