Sperm Agglutination in Infertile Men and The Success Rate of Intrauterine Insemination in Rumah Sakit Ibu dan Anak Puri Bunda Denpasar
Downloads
Background: Every human being, especially a married couple, wants children. Obstacles to obtaining children are called infertility. One of the Assisted Reproductive Technology (ART) procedures used for treating infertility is intrauterine insemination (IUI), a non-invasive procedure with affordable costs. The success of IUI is influenced by many factors, one of which is sperm agglutination.
Objective: This study determined the relationship between sperm agglutination and the success rate of the IUI procedure.
Methods: The study is a descriptive-analytic study with a cross-sectional approach. The sample collection technique uses non-probability. The data used were medical records of male patients diagnosed with infertility, aged 25-45 years, and undergoing IUI procedures at the Rumah Sakit Ibu dan Anak Puri Bunda Denpasar from January to July 2022.
Results: Of the 91 samples obtained, 9 people experienced sperm agglutination (9,9%), and 82 people did not experience sperm agglutination (90,1%). The success rate of the IUI procedure was 29 people (31,9%), 1 person (11.1%) experiencing sperm agglutination, and 28 people (34,1%) not experiencing sperm agglutination. Fisher's Exact test carried out has obtained a result (p=0.263). And the value of the odds ratio (OR) obtained=0.241)
Conclusion: This study concluded that there is no significant relationship between sperm agglutination in infertile men and the success rate of the IUI procedure. The value of OR showed sperm agglutination is not included in the factors that affect the success rate of IUI.
Keywords: Sperm Agglutination, Intrauterine Insemination, Male Infertility
Lindsay TJ, Vitrikas KR. Evaluation and treatment of infertility. Am Fam Physician 2015; 91: 308–314.
Muhamad Ikhsan, Andi Muh. Multazam, Andi Asrina. Infertilitas Pada Pasangan Suami Istri Di Kota Makassar. Wind Heal J Kesehat 2019; 2: 285–296.
Saraswati A. Infertility. Med J Lampung Univ 2015; 4: 1–2.
Ferial EW, Soekendarsi E, Utami IP. Deteksi Dini Suspek Infertilitas Berdasarkan Analisis Makroskopik Spermatozoa Manusia. In: Prosiding Seminar Nasional Biologi dan Pembelajarannya. 2018.
Persandi. Standarisasi Analisa Semen Nasional. 2015.
Allow AK, A SSA, Maryam B, et al. Sperm Agglutination, Sperm Shaky Head Movement and Sperm-Cervical Interaction Tests could be enough for Diagnosis of Immunological Infertility? J Gynecol Women's Health. J Gynecol Woman's Heal 2017; 3: 2–5.
Berger GK, Smith-Harrison LI, Sandlow JI. Sperm agglutination: Prevalence and contributory factors. Andrologia 2019; 51: e13254.
WHO. WHO laboratory manual for the examination and processing of human semen Sixth Edition. 2021.
Sunderam S, Kissin DM, Zhang Y, et al. Assisted Reproductive Technology Surveillance - United States, 2016. Morb Mortal Wkly report Surveill Summ (Washington, DC 2002) 2019; 68: 1–23.
Allahbadia GN. Intrauterine Insemination: Fundamentals Revisited. Journal of obstetrics and gynaecology of India 2017; 67: 385–392.
Rao KA, Agarwal A, Srinivas M. Andrology Laboratory Manual 1th ed. Andrology Laboratory Manual. 1/e. New Delhi: Jaypee Digital, 2010. Epub ahead of print 2010. DOI: 10.5005/jp/books/11172.
S GN. Hubungan Antara Jumlah Leukosit Pada Cairan Semen Dengan Motilitas Sperma Pada Pria Pasangan Infertil Di Rumah Sakit Adenin Adenan Medan. Medan, 2013.
Dhyani IAD, Kurniawan Y, Negara MO. Hubungan Antara Faktor-Faktor Penyebab Infertilitas Terhadap Tingkat Keberhasilan Ivf-Icsi Di Rsia Puri Bunda Denpasar Pada Tahun 2017. J Med Udayana 2020; 9: 22–27.
Safi J, Sharma RK, Agarwal A. Intrauterine Insemination. In: Infertility First Edition. 2011; 114–126.
Rachmiawaty A, Djuwantono T, Sasotya RMS. Analisis Faktor yang Memengaruhi Keberhasilan Kehamilan pada Inseminasi Intrauterin. Indones J Obstet Gynecol Sci; 1. Epub ahead of print 2018. DOI: http://dx.doi.org/10.24198/obgynia.v1n1.42.
Nordhoff V, Kliesch S. Sperm Preparation for Therapeutic IVF. 2017.
Ashok A, K SR, Tahir B. Sperm Preparation and Selection Techniques. In: Medical and Surgical Management of Male Infertility. 1/e. Jaypee Digital, 2014. Epub ahead of print 2014. DOI: 10.5005/jp/books/11840_29.
Vij R, Storer B, Peck J, et al. Does the Presence of Agglutination or White Blood Cells in the Semen Preparation for Intrauterine Insemination Affect the Couple's Chance of Conceiving? Fertility and Sterility. 2011; 95: 64.
Felemban A, Hassonah SM, Felimban N, et al. Sperm Surface Antibodies: IUI vs. IVF Treatment. Obstet Gynecol Res; 1.
Govindarajan M, Mallikarjunan S, Ahmed HSR, et al. Retrospective Study of Factors Affecting Intrauterine Insemination Pregnancy Outcome: The Impact of Male Habits and Working Environment. J Hum Reprod Sci 2017; 10: 114–118.
Copyright (c) 2023 Indonesian Andrology and Biomedical Journal
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
