Neonatal Sepsis in Low Birth Weight Infants in Dr. Soetomo General Hospital
Downloads
Infections of the newborn are a significant cause of mortality. Preterm infant have a high risk sepsis.. The incidence of neonatal sepsis is 1 to 10 cases per 1000 live births and 1 per 250 live premature births. To describe the characteristics of neonatal sepsis in the
low birth weight infant in the neonatal intensive care unit Dr. Soetomo Hospital. Retrospective analysis. The data were collected from the medical record of low birth weight infants who were diagnosed as sepsis in neonatal care unit of Dr. Soetomo Hospital between January 2010 to June 2010 with purposive sampling. Descriptive analysis of risk factor of sepsis and blood culture of the patient was calculated. Chi-square analysis was performed in the laboratorium data. Characteristics sample: male vs female 61% vs 39%, outcome of sepsis in LBW was death 69%, alive 25%, risk of infection: turbid amniotic fluid 21%, asphyxia 33%. Laboratorium data leucopenia and thrombocytopenia (P < 0.05). Blood culture: Klebsiella pnemoniae. The incidence and mortality of neonatal sepsis in LBW infants was still high. Asphyxia, turbid amniotic fluid, leucopenia and thrombocytopenia were associated with sepsis. pneumoniae was the most common organisms in the LBW sepsis infants.
neonatology pathophysiology and management of the newborn
Philadelphia: Lippincott Williams Wilkins; 2005. p. 1235–73.
2. Puopolo K. Bacterial and fungal infections. In: Cloherty J, Eichenwald EC, Stark AR, editor. Manual of neonatal care. 5th ed. Philadelphia: Lippincott William & Wilkins; 2008. p. 275–300.
3. Rohsiswatmo R. Kontroversi diagnosis sepsis neonatorum. In: Hegar B, Trihono PP, Ifran EB, editor. Update in neonatal infection. Jakarta: Departemen Ilmu Kesehatan Anak FKUI-RSCM; 2005. p. 32–43.
4. Klein J, Marcy SM. Bacterial sepsis and meningitis. In: Remington J,Klein JO, editor. Infectious diseases of the fetus and newborn infant. 3rd ed. Philadelphia: W.B. Saunders Co; 1990. p. 610–25.
5. Jain N, Jain VM, Maheswari S. Clinical profile of neonatal sepsis.
Kathmandu Univ Med J. 2003; 1: 117–20.
6. Washburn T, Medearis DN, Childs B. Sex differences in suceptibility to infections. Pediatrics. 1985; 35: 57–60.
7. Purtillo D, Sullivan JL. Immunological basis for soperior survival of
females. Am J Dis Child. 1989; 133: 1251–5.
8. Simiyu E. Morbidity and mortality of the low birth weight infants in newborn unit in Kenyatta National Hospital, Nairobi. East African
Med J. 2004; 81: 367–74.
9. Ringer S. Care of the extremley low birth weight infant. In: Cloherty J, Eichenwald EC, Stark AR, editor. Manual of neonatal care.
Philadelphia: Lippincott Williams & Wilkins; 2008. p. 78–85.
10. Bennel R, Nord CE. Development of the faecal anaerobic microflora after caesarean section and treatment with antibiotics in newborn infants. . Infection. 1987; 15: 332–6.
11. Sung N, Lee SG, Kim MJ, Kim YH, Yang S, Hwang IT, et al. The changes of Intestinal normal flora in neonates for seven days postnatally. Korean J Pediatr Gastroenterol Nutr. 2006; 9: 162–8.
12. Gupta R. Care of low birth weight neonate. JK Science. 2008; 10:
158–9.
13. Shah G, Budhathoki S, Das BK, Mandal RN. Risk factors in early
neonatal sepsis. Kathmandu Univ Med Journal. 2006; 4: 187–91.
14. Bang A, Reddy HM, Bang RA, Desmukh MD. Why do neonates die
in rural Gatchirolli, India? Estimating population attirbutable risks
and contribution of multiple morbities for identifying a strategy to prevent deaths. J Perinatol. 2005; 25: S35–43.
15. Janine M, Jason MD. Infectious disease-related deaths of low birth
weight Infants, United States, 1968 to 1982 Pediatrics. 1989; 84:
296–303
16. Utomo M. Risk factors of neonatal sepsis: a preliminary study in Dr Soetomo Hospital. In J Trop Infec Dis. 2010; 1: 23–6.
17. Goorin A, Cloherty JP. Thrombocytopenia. In: Cloherty J, Eichenwald EC, Stark AR, editor. Manual of neonatal care. 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2008. p. 455–62.
18. Torkaman M, Afsharpaiman SH, Hoseini MJ, Moradi M, et al.
Platelets count and neonatal sepsis: a high prevalence of Enterobacter spp Singapore Med J. 2009; 50: 482–5.
19. Lee W, Cho J, Yoo S, Lee C, et al. Platelet count and mean platelet volume in low birth weight infants (≤2,000 g) with sepsis. Korean J Pediatr Gastroenterol Nutr. 2007; 50: 643–8.
20. Waseem R, Khan m, Izhar TS, Qureshi AW. Neonatal sepsis.
Professional Med J. 2005; 12: 451–6.
21. Sundaram V, Kumar P, Dutta S, Mukhophdhyay K, et al. Blood
culture confirmed bacterial sepsis in neonates in a North Indian tertiary care centre: changes over the last decade. Jpn J Infect Dis. 2009; 62:46–50.
The Indonesian Journal of Tropical and Infectious Disease (IJTID) is a scientific peer-reviewed journal freely available to be accessed, downloaded, and used for research. All articles published in the IJTID are licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, which is under the following terms:
Attribution — You must give appropriate credit, link to the license, and indicate if changes were made. You may do so reasonably, but not in any way that suggests the licensor endorses you or your use.
NonCommercial — You may not use the material for commercial purposes.
ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.
No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
