The Treatment of A Case of Feline Panleukopenia Virus in a Mixed Persian Cat

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Background: Feline panleukopenia virus (FPV) is a highly contagious and frequently fatal disease, particularly affecting unvaccinated juvenile cats. Clinical manifestations typically include leukopenia, diarrhea, dehydration, vomiting, and depression. The disease exhibits high morbidity and mortality rates, especially in young animals without prior immunization. Purpose: This report aims to provide clinical insight into the diagnosis and symptomatic management of FPV in domestic cats. Case: An 8-month-old unvaccinated female cat weighing 2.3 kg was presented with signs consistent with panleukopenia. The patient had not received deworming treatment and lived in a semi-outdoor environment with three other cats. Physical examination focused on the oral cavity, nasal passages, eyes, ears, and abdomen. Hematological findings supported suspicion of viral infection. The history revealed that the patient’s littermates had died after exhibiting similar symptoms. Case Management: Therapy focused on symptomatic treatment, including the administration of broad-spectrum antibiotics (ceftriaxone) to prevent secondary bacterial infections and reduce the risk of septicemia. Gastric protection was provided using ranitidine to inhibit gastric acid secretion and prevent complications such as ulcers and esophageal erosion. Supportive management also included fluid therapy and antidiarrheal care tailored to the patient's clinical status. Conclusion: Prompt diagnosis and appropriate symptomatic management significantly influence the outcome of FPV cases. Preventive strategies, including vaccination and routine deworming, remain essential in reducing the incidence and severity of infection. This case highlights the importance of early intervention and individualized treatment in improving recovery and survival rates in cats affected by panleukopenia.
Adams, J., 2015. Fluid Therapy in adult cattle. UK-Vet Livestock, 20(1), 32-37.
Awad, R., Khalil, W., and Attallah, A., 2018. Epidemiology and Diagnosis of Feline Panleukopenia Virus in Egypt: Clinical and Molecular Diagnosis in Cats. Veterinary World, 11(5), 578-584.
Brown, L. K., and Davis, A. L., 2024. Acute Diarrhea in Cats: Pathophysiology and Management Strategies. Journal of Feline Medicine and Surgery, 21(3), 210-220.
Garigliany, M., Gilliaux, G., Jolly, S., Casanova, T., Bayrou, C., Gommeren, K., Fett, T., Mauroy, A., Lévy, E., Cassart, D., Peeters, D., Poncelet, L., and Desmecht, D., 2016. Feline Panleukopenia Virus in Cerebral Neurons of Young and Adult Cats. BMC Veterinary Research, 12 (1), 1-10.
Gillespie, T., Song, Q., Inskeep, M., Stone, S., and Murtaugh, M., 2018. Effect of Booster Vaccination with Inactivated Porcine Epidemic Diarrhea Virus on Neutralizing Antibody Response in Mammary Secretions. Viral Immunology, 31(1), 62-68.
Gülersoy, E., Balıkçı, C., Kısmet, E., Günal, İ., Şahan,A. , Güçlü, M.A., and Ok, M., 2023. Renal Ultrasonography Findingsin Cats with Feline Infectious Peritonitis. Van Veterinary Journal, 34(1), 63-69.
Kiselev, A., Shcherbinin, S., and Galkina, T., 2023. Feline Panleukopenia (review). Veterinary Science Today, 5(1), 303-307.
Litster, A., Wu, C., and Leutenegger, C., 2015. Detection of Feline Upper Respiratory Tract Disease Pathogens Using a Commercially Available Real-Time PCR Test. Veterinary Journal, 206(2), 149-53.
Marlissa F. C. M., Suartha, I. N., and Widyastuti, S. K., 2022. Laporan Kasus penanganan Panleukopenia pada Kucing Kampung Usia Muda yang Belum Pernah di Vaksinasi. Indonesia Medicus Veterinus, 11(4), 579-593.
Pandey, S., 2022. Feline Panleukopenia Infections Treatment and Control In Nepal. European Journal Of Veterinary Medicine, 2(1), 1-5.
Priambudi, M., Haskito, A., Inayah, K., and Adrenalin, S., 2022. Detection of Feline Panleukopenia with Antigen Test Kit. ARSHI Veterinary Letters, 6(1), 3-4.
Smith, J. P., and Johnson, R. A., 2023. Efficacy of Ranitidine in the Treatment of Gastric Acid Related Disorders in Cats. Veterinary Gastroenterology Journal, 18(2), 122-134.
Taylor, M. B., and Harris, P. W., 2023. Immune Suppression and Secondary Infections in Cats With Feline Panleukopenia Virus. Journal of Veterinary Internal Medicine, 37(5), 873-885.
Thomas, H. G., and Parker, L. M., 2023. The Rapid Progression and Mortality Rates of Feline Panleukopenia in Kittens. Journal of Feline Medicine and Surgery, 21(6), 520-528.
Williams, S. M., and Jensen, A. P., 2023. Clinical Manifestations of Feline Panleukopenia: A Review of Symptoms and Diagnostic Strategies. Journal of Feline Medicine and Surgery, 23(5), 345-357.
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