Association between Nutritional Knowledge and Immunonutrients Intake with Immunity Status Post-Pandemic COVID-19 in College Students
Hubungan antara Pengetahuan Gizi dan Asupan Zat Imunonutrisi dengan Status Imunitas Pascapandemi Covid-19 pada Mahasiswa Fakultas Kedokteran Universitas Lampung
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Background: The occurrence of COVID-19 pandemic has affected various aspects of life. Several studies have shown that the ability to recover and avoid COVID-19 infection depends on the level of immunity, which is influenced by the intake of immunonutrients. However, healthy eating habits, such as the consumption of these immononutrients, are influenced by a good nutrition understanding.
Objectives: This study aimed to determine the association between nutritional knowledge and immunonutrients intake with immunity status post-pandemic COVID-19 in college students.
Methods: The study procedures were carried out using an observational analytical method with a cross-sectional design. The sample population comprised 104 first-year students from Medical Education Study Program at Medical Faculty of Lampung University. Students were determined using the unpaired categorical comparative analytics sample size formula and selected with a straightforward simple random sampling method. Data were collected using a questionnaire, including nutritional knowledge, immunonutrients intake, and immune status. Analysis was carried out using Chi-Square test and logistic regression.
Results: The result showed that 51.9% of respondents had decreased immunity status. The bivariate test revealed that protein intake (p-value<0.001), zinc (p-value=0.006), iron (p-value<0.001), vitamin A (p-value<0.001), and vitamin C (p-value=0.002) had a relationship with immunity status, while nutritional knowledge (p-value=0.708) had no association. In addition, the factors most related to immunity status were protein, iron, and vitamin C intake.
Conclusions: Immunonutrients intake is a factor that directly influenced immunity status, while nutritional knowledge is an indirect factor.
World Health Organization (WHO). Advice for the public: Coronavirus Disease (COVID-19). who.int/emergencies/diseases/novel-coronavirus-2019/advice-for-publics (2020).
Ministry of Internal Affairs of Indonesia. Implementation of Community Activities Restrictions Level 4 Coronavirus Disease 2019 in Java and Bali Region. (2021).
Aeni, N. Pandemi COVID-19: Dampak Kesehatan, Ekonomi, dan Sosial COVID-19 Pandemic: The Health, Economic, and Social Effects. 17, 17–34 (2021).
Yuliyanto, R. & Yamin, R. D. The Impact of Learning Loss During a Pandemic Among Students. vol. 2 (2022).
Ardiaria, M. Peran Vitamin D Dalam Pencegahan Influenza dan COVID-19. Journal of Nutrition and Health 8, 79–85 (2020).
Adijaya, O. & Perwira Bakti, A. Peningkatan Sistem Imunitas Tubuh Dalam Menghadapi Pandemi Covid-19. Jurnal Kesehatan Olahraga 9, 51–60 (2021).
Munteanu, C. & Schwartz, B. The relationship between nutrition and the immune system. Frontiers in Nutrition vol. 9 Preprint at https://doi.org/10.3389/fnut.2022.1082500 (2022).
Akbar, A., Hardy, F. & Maharani, F. Hubungan Tingkat Pengetahuan dan Sikap Terhadap Tindakan Pencegahan COVID-19 Pada Mahasiswa Kesehatan Masyarakat UPN Veteran Jakarta. Seminar Nasional Kesehatan Masyarakat 2020 98–110 (2020).
Azrimadaliza, A., Khairany, Y. & Putri, R. Pengetahuan, Sikap dan Perilaku Gizi Keluarga dalam Meningkatkan Imunitas Selama Pandemi Covid-19. Jurnal Ilmiah Kesehatan 20, 40–44 (2021).
Angraini, D. I. & Ayu, R. The Relationship Between Nutritional Status and Immunonutrition Intake with Immunity Status. JUKE 4, 158–165 (2014).
Ramadhia, A., Harna, Sa’pang, M. & Nadiyah. Hubungan Asupan Zat Gizi Mikro, Durasi Tidur, Indeks Massa Tubuh dan Status Imun Pegawai Balitbang Hukum dan HAM. Journal of Nutrition College 10, 328–334 (2021).
Sutrisno, E. Post-Pandemic Economic Recovery Strategy Through The UMKM And Tourism Sector. Jurnal Lembaga Ketahanan Nasional Republik Indonesia 9, 641–660 (2020).
Vaillant, A., Sabir, S. & Jan, A. Physiology Immune Respons. (StatsPearls Publishing, 2022).
Wanty, Widyastuti, N. & Probosari, E. Asupan Zat Gizi Makro, Status Gizi dan Status Imun Pada Vegetarian dan Non-vegetarian. Journal of Nutrition College 6, 234–240 (2017).
da Silveira, M. P. et al. Physical exercise as a tool to help the immune system against COVID-19: an integrative review of the current literature. Clinical and Experimental Medicine vol. 21 15–28 Preprint at https://doi.org/10.1007/s10238-020-00650-3 (2021).
Yaribeygi, H., Panahi, Y., Sahraei, H., Johnston, T. P. & Sahebkar, A. The impact of stress on body function: A review. EXCLI Journal vol. 16 1057–1072 Preprint at https://doi.org/10.17179/excli2017-480 (2017).
El-Radhi, A. Clinical Manual of Fever in Children. (2019). doi:10.1136/adc.2007.
Suryanto, D., Basid, A., Kusuma Negara, C. & Kalimantan Muhammad Arsyad Al Banjari, I. The Effect of Community Nutrition Education Innovation Based on Social Media Marketing on Knowledge, Attitude, And Behavior To Prevent Stunting under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). Jurnal eduhealth 13, 2022 (2022).
Hertzler, S. R., Lieblein-Boff, J. C., Weiler, M. & Allgeier, C. Plant proteins: Assessing their nutritional quality and effects on health and physical function. Nutrients vol. 12 1–27 Preprint at https://doi.org/10.3390/nu12123704 (2020).
Wijayanti, A., Margawati, A. & Wijayanti, H. Hubungan Stres, Perilaku Makan, Dan Asupan Zat Gizi dengan Status Gizi Pada Mahasiswa Tingkat Akhir. Journal of Nutrition College 8, 1–8 (2019).
Skrajnowska, D. & Bobrowska-Korczak, B. Role of zinc in immune system and anti-cancer defense mechanisms. Nutrients vol. 11 Preprint at https://doi.org/10.3390/nu11102273 (2019).
Cronin, S. J. F., Woolf, C. J., Weiss, G. & Penninger, J. M. The Role of Iron Regulation in Immunometabolism and Immune-Related Disease. Frontiers in Molecular Biosciences vol. 6 Preprint at https://doi.org/10.3389/fmolb.2019.00116 (2019).
Abuga, K. M., Nairz, M., MacLennan, C. A. & Atkinson, S. H. Severe anaemia, iron deficiency, and susceptibility to invasive bacterial infections. Wellcome Open Research vol. 8 Preprint at https://doi.org/10.12688/wellcomeopenres.18829.1 (2023).
Huang, Z., Liu, Y., Qi, G., Brand, D. & Zheng, S. G. Role of vitamin A in the immune system. Journal of Clinical Medicine vol. 7 Preprint at https://doi.org/10.3390/jcm7090258 (2018).
Carr, A. C. & Maggini, S. Vitamin C and immune function. Nutrients vol. 9 Preprint at https://doi.org/10.3390/nu9111211 (2017).
Jezewska-Zychowicz, M. & Plichta, M. Diet Quality, Dieting, Attitudes and Nutrition Knowledge: Their Relationship in Polish Young Adults—A Cross-Sectional Study. Int J Environ Res Public Health 19, (2022).
Maggini, S., Pierre, A. & Calder, P. C. Immune function and micronutrient requirements change over the life course. Nutrients vol. 10 Preprint at https://doi.org/10.3390/nu10101531 (2018).
Yang, L. et al. Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy. Journal of Hematology and Oncology vol. 16 Preprint at https://doi.org/10.1186/s13045-023-01453-1 (2023).
Kell, D. B., Heyden, E. L. & Pretorius, E. The Biology of Lactoferrin, an Iron-Binding Protein That Can Help Defend Against Viruses and Bacteria. Front Immunol 11, (2020).
Wessels, I., Maywald, M. & Rink, L. Zinc as a gatekeeper of immune function. Nutrients vol. 9 Preprint at https://doi.org/10.3390/nu9121286 (2017).
Abbaspour, N., Hurrell, R. & Kelishadi, R. Review on Iron and Its Importance for Human Health. Journal of Research in Medical Sciences (2014).
Semba, R. Vitamin A Story. in World Review of Nutrition and Dietetic (ed. Koletzko, B.) (2012).
Shahbaz, U. et al. Role of vitamin C in preventing of COVID-19 infection, progression and severity. AIMS Microbiology vol. 8 108–124 Preprint at https://doi.org/10.3934/microbiol.2022010 (2022).
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