The Role of Hyperbaric Oxygen to Platelet Aggregation in Diabetic Patients Type II (NIDDM)
Vol. 1 No. 2 (2010)
Articles
May 3, 2010
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level of HbA1c (4–5,9), as long as this research they couldn't take their Oral Hipoglikemic Agent, Oral Anti Trombotic, vitamin C and vitamin E. They are divided into 2 group: group of HBO 100% O 2,4 ATA for 3x30 minutes with interval 5 minutes to inhalate air once a day daily for 5 days subsequently and the extraction of data (PAT) had been held before oxygenation hyperbaric therapy at the first day and the end of fifth days, in control group only giving 20% O2 with the pressure 1 ATA for 90 minutes once a day daily for 5 days subsequently and the extraction of data (PAT) had been held
before normoxia normobaric therapy at the first day and the end of fifth days. The results were significant decrease of the platelet's aggregation level especially percent of aggregation after 5 days from 76,56 ± 8,06 become 69,13 ± 6,03. Latent Periode has also decrease from 28,75 ± 3,87 become 25,75 ± 2,82. Speed of Aggregation has also decrease from 66,25 ± 3,17 become 62,50 ± 3,44. Index of Aggregation has also decrease from 0,763 ± 0,071 become 0,581 ± 0,083.
Using paired t-test, it could be seen the decrease of Latent Periode (p= 0,001) and index of aggregation (p= 0,000) significantly after exposure of oxygenation hyperbaric HBO 2,4 ATA 100% O
3í—30 minutes with interval 5 minutes inhalate air once a day for 5 days,subsequently. Speed of aggregation (p = 0,022) and percent of aggregation (p= 0,013) are nonsignificantly. The conclusion of this research is that oxygenation hyperbaric 2,4 ATA 100% O2 3í—30 minutes with interval 5 minutes inhalate air once a day for 5 days,subsequently could decrease latent periode, speed of aggregation, index of aggregation and percent of aggregation in NIDDM
Widiyanti, P. (2010). The Role of Hyperbaric Oxygen to Platelet Aggregation in Diabetic Patients Type II (NIDDM). Indonesian Journal of Tropical and Infectious Disease, 1(2), 77–81. https://doi.org/10.20473/ijtid.v1i2.2170
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Tjokroprawiro A, 1997. Diabetes Update - 1997 A. Naskah Lengkap Surabaya Diabetes Update-II 1997, Surabaya; Pusat Diabetes dan Nutrisi RSUD Dr. Soetomo-FK Unair, hal. 1–21.
Wolfe RR, 1998. Metabolic interactions between glucose and fatty acidsMetabolic interactions between glucose and fatty acids in humans. Am J Clin Nutr Vol. 67(3) Suppl 5, p. 12–18.
Ditzel J, 1967. The in vivo Reactions of The Small Blood Vessels to Diabetes Mellitus. acta med. scand. suppl 476, p. 123. Epsthein I, 1998. Diabetes Mellitus. text Book of Hyperbaric Medicine, 2nd ed., Toronto, Hogrefe and Huber, p. 368–369.
Ersoz G, Ocakcioglu B, Bastug M, Ficicilar H, Yavuzer S, 1998. Trombosit Agregation and Release Function in Hyperbaric Oxygenation, Ankara University Faculty of Medicine, Department of Physiology, Turkey, undersea Hyperb Med, Winter; 25(4): 229–32
Foster DW, 1998. Diabetes Mellitus. Williams text Book of Endocrinology, 9th edition, USA: WB Saunders Company, p. 1014–1015. Foster DW, 1998. Diabetes Mellitus. In: Harrison. Harrison's principle of internal Medicine, 14th ed, New York: McGraw-Hill, p. 2060–2070.
Hendromartono, 1997. Status Hemoreologi pada Kualitas Hidup Penderita Diabetes Mellitus. Dalam: Editor: Tjokroprawiro A, Hendromartono, Sutjahjo A, Tandra H,Pranoto A,Murtiwi S, dkk. naskah lengkap surabaya diabetes update iii november 1997 .Surabaya, hal. 14–15.
Ito T, Yufu K, Mori A, Packer L, 1996. Oxidative Stress alters arginine metabolism in rat brain: effect of sub-convulsive hyperbaric oxygen exposure. neurochem int 29: p. 187–195. LaCroix KA, Davis GL, Schneider DA, Lavoie P, Kintzing E, Waterfield DA, 1990. The effects of acute exercise and increased atmpspheric pressure on the hemostatic mechanism and plasma catechol amine levels. thromb res 57: p. 717–728.
McMillan DE, 1987. Hematologic Changes in Diabetes. In: Editors: Andreani D, Crepaldi G, diabetic complication Early diagnosis and treatment. A Willey medical Publication, New York, p. 349. Moncada S, Higgs A, 1993. The L - arginine - nitric oxide pathway. n Engl J Med 329: p. 2002.
Muller R, Lebrach F, 1986. Hemorheology and Diabetes Mellitus. Naskah lengkap Konas i perkeni, Jakarta, 22–25 November, hal. 1.
Nadler JL, Natarajan R, 2000. Oxidative Stress, Inflammation and DiabeticOxidative Stress, Inflammation and Diabetic Complications. In (LeRoith D, Taylor SI, Olefsky JM, eds.) diabetes Mellitus, a fundamental and clinical text, 2nd edition, Lippincott Williams and Wilkins, A wolters Kluwer Company, Philadelphia, p. 1008–1016
Nong Z, Hoylaerts M, Van Pelt N, Collen D, Janssens S, 1997. NitricNitric Oxide Inhalation Inhibits Platelet Aggregation and Platelet- Mediated Pulmonary Thrombosis in Rats. Circulation Research Vol. 81, No. 5 November, p. 865–869. Oriani G, Maroni A, Wattel F, 1995. Handbook on Hyperbaric Medicine. Berlin: Springer, p. 531–534.
Oury TD, Ho Y, Piantadosi CA, et.al, 1992. Extracellular superoxide dismutase, nitric oxide and central nervous system O toxicity. procnatl acad sci 89: p. 9715–9719
Radomsky MW, Moncada S, 1993. The biological and pharmacological role of nitric oxide in platelet function. In: Authi KS, et al. eds. Mechanism of platelet activation and control. New York: Plenum Press, p. 251–261.
Schimdt H H, Lohmann S, Walter U, 1993. The Nitric Oxide and c-GMP signal transduction system. Biochim Biophys acta 1178: p. 153.
Semiardji G, 1999. Stress Emosional Pada Pasien Diabetes. Dalam:Stress Emosional Pada Pasien Diabetes. Dalam: penatalaksanaan diabetes Mellitus terpadu, Pusat Diabetes dan Lipid RSUP Nasional Dr. Cipto Mangunkusumo Fakultas Kedokteran Universitas Airlangga- Departemen Kesehatan Republik Indonesia-World Health Organization, CV Aksara Buana, Jakarta, hal. 253–260.
Sherwood L, 1994. Human physiology. West Publishing Company, p. 22–28.
Soeharjono S, 1985 . Hemoreologi pada Penderita Diabetes Mellitus. naskah lengkap simposium Konsep Baru penanganan Gangguan pembuluh darah, Surabaya, 14 Desember 1985.
Stacy P, Borushek A, 1986. cookbook for diabetics plus diet Guide. Western Australia: West Perth, p. 60.
Storlien H, 1993. obesity weight control and muscle metabolism. In: Proceeding of 9th Biennial Conference: Exercise, Metabolism and Nutrition, p. 6–12.
Soekardji K, 1999. Penatalaksanaan Gizi Pada Diabetes Mellitus. Dalam: penatalaksanaan diabetes Mellitus terpadu, Pusat Diabetes dan Lipid RSUP Nasional Dr. Cipto Mangunkusumo Fakultas Kedokteran Universitas Airlangga- Departemen Kesehatan Republik Indonesia-World Health Organization, CV Aksara Buana, Jakarta, hal. 33–41.
Suyono S, 1996. Masalah DM di Indonesia,. Buku ajar ilmu penyakit dalam. Edisi 3, Jakarta: Balai Penerbit FKUI, hal. 597–600.Edisi 3, Jakarta: Balai Penerbit FKUI, hal. 597–600.
Tjokroprawiro A, 1997. Diabetes Update - 1997 A. Naskah Lengkap Surabaya Diabetes Update-II 1997, Surabaya; Pusat Diabetes dan Nutrisi RSUD Dr. Soetomo-FK Unair, hal. 1–21.
Wolfe RR, 1998. Metabolic interactions between glucose and fatty acidsMetabolic interactions between glucose and fatty acids in humans. Am J Clin Nutr Vol. 67(3) Suppl 5, p. 12–18.
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