THE ROLE OF HYPERBARIC THERAPY IN THE GROWTH OF CANDIDA ALBICANS
Background: Candida albicans is opportunistic pathogen fungi which cause many disease in human such as reccurrent apthous stomatitis, skin lesions, vulvavaginitis, candiduria and gastrointestinal candidiasis. Aim: Infection mechanism of C. albicans is very complex including adhesion and invasion, morphology alteration from khamir form cell to filamen form (hifa), biofilm forming and the avoidance of host immunity. Method: The ability of C. albicans to adhere to the host cell which is act as important factor in the early colonization and infection. Result: The phenotype alteration to be filament form let the C. albicans to penetrate to the epithelium and play important role in infection and separation C. Albicans to the host cell. Hyperbaric oxygen is the inhalation of 100 percent oxygen inside hyperbaric chamber that is pressurized to greater than 1 atmosphere (atm). Conclusion: The organism was found to be
inhibited within a pressure/time range well tolerated by human subjects, suggesting that hyperbaric oxygen might be used successfully in treating human candidiasis.
Indonesian Journal of Tropical and Infectious Disease by Institute of Tropical Disease, Universitas Airlangga is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. Permissions beyond the scope of this license may be available at http://e-journal.unair.ac.id/index.php/IJTID/. Both authors and Indonesian Journal of Tropical and Infectious Disease agree with the following attribution of journal:
1. Indonesian Journal of Tropical and Infectious Disease (IJTID) agrees to acknowledge the authors' articles published in Open Journal Access of IJTID
2. The authors agree to acknowledge Indonesian Journal of Tropical and Infectious Disease as the site of original publication of the articles
3. As the authors agree to publish their articles in IJTID, the copyright of the articles is fully transferred to IJTID.
4. The Creative Commons Attribution-ShareAlike 4.0 International licensing applied in IJTID allows IJTID share and adapt the articles by giving appropriate credit and distributing them to the readers for free under the same license.
Articles submitted in IJTID should include the "Copyright Transfer Agreement" preceding the article publication. Authors can download the "Copyright Transfer Agreement" for the purpose of publication.