MICROBIAL PATTERNS OF HOSPITALIZED HIV POSITIVE  PATIENTS ADMITTED IN DR. SOETOMO GENERAL HOSPITAL,  SURABAYA INDONESIA

Feriawan Tan; Erwin Astha Triyono; Manik Retno Wahyunitisari

doi:10.20473/jvhs.V5.I1.2021.1-11

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Feriawan Tan Student of Medical, Faculty of Medicine, Universitas Airlangga, Indonesia https://orcid.org/0000-0003-0799-2199
Erwin Astha Triyono
erwintriyono@yahoo.com
Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Indonesia
Manik Retno Wahyunitisari Departement of Medical Microbiology, Faculty of Medicine, Universitas Airlangga, Indonesia

Vol. 5 No. 1 (2021): July 2021 | JOURNAL OF VOCATIONAL HEALTH STUDIES

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July 31, 2021

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Background: HIV patients with a weak immune system are very vulnerable to opportunistic infections, can trigger systemic endothelial activation and end up as a condition of sepsis. In Indonesia currently, there is no bacterial epidemiological mapping of the etiology of opportunistic infections in HIV patients. Purpose: To determine the pattern of bacteria that cause opportunistic infections and their antibiotic sensitivity in HIV patients. Method: Prospective observational study design. Data were obtained from medical records of hospitalized patients at RSUD Dr. Soetomo Surabaya from August 2019 - February 2020. Result: Out of 64 patients, 83 specimens were found with the most types of gram-negative bacteria 44.6%, while gram-positive bacteria were 15.7% and a mix of 2.4% and 37.3% negative culture. The highest prevalence of gram-negative bacteria was Klebsiella pneumoniae (35.15), followed by Escherichia coli (10.8%), Pseudomonas aeruginosa (8.1%), and Acinetobacter baumanii (8.1%). The highest prevalence of gram-positive bacteria was Streptococcus mitis / oralis (30.7%), followed by Staphylococcus aureus (23.1%) and Staphylococcus epidermidis (15.4%). Among gram-negative bacteria antibiotic, Cefoperazone-sulbactam showed the greatest sensitivity, following by Amikacin, Gentamycin and Piperacillin-tazobactam; while among gram-positive bacteria are Chloramphenicol, Linezolid, and Vancomycin. Almost all isolates showed resistance to Ampicillin. Conclusion: Bacteria pattern that caused opportunistic infection in RSUD Dr. Soetomo is K. pneumonia as most common gram-negative bacteria followed by E. coli, P. aeruginosa and A. baumanii; while the most gram-positive bacteria found are S. mitis/oralis and S. aureus. Among antibiotic used, Ampicillin showed the lowest sensitivity to almost all bacteria isolates.

Tan, F., Triyono, E. A., & Wahyunitisari, M. R. (2021). MICROBIAL PATTERNS OF HOSPITALIZED HIV POSITIVE PATIENTS ADMITTED IN DR. SOETOMO GENERAL HOSPITAL, SURABAYA INDONESIA. Journal of Vocational Health Studies, 5(1), 1–11. https://doi.org/10.20473/jvhs.V5.I1.2021.1-11

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