INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS

Firnanda Iptita Dewi, Manik retno Wahyunitisari

= http://dx.doi.org/10.20473/jvhs.V1.I3.2018.113-116
Abstract views = 2259 times | downloads = 20625 times

Abstract


Background: gram-negative bacteria-salmonella typhi and gram-positive bacteria-staphylococcus aureus are types of bacteria that cause infectious disease among several areas in Indonesia. Staphylococcus aureus often found in skin lesions injury. Red ginger extract (Zingiber officinale var rubrum) has been known for its medicinal value especially as an antibacterial agent. Purpose: This study aims to test the ability of Zingiber officinale var rubrum on inhibiting the growth of Staphylococcus aureus. Methods: the activity of the antibacterial agent was calculated based on Minimum Inhibitory Concentration (MIC) using dilution method. Minimum Inhibitory Concentration of extract was determined by incubating bacteria with the extract overnight at 37 0C. Changes in turbidity and inhibition on bacterial growth were then observed. Result: The results show that minimum concentration for inhibitory effect was 1000 μg/mL.Conclusion: extract of Zingiber officinale var rubrum have an inhibitory effect on the growth of Staphylococcus aureus but no activity of killing bacterial was observed on the concentration given.


Keywords


Zingiber officinale var rubrum; Extract; Inhibitory; Staphylococcus aureus

Full Text:

PDF

References


Ali, B., Al-Wabel, N.A., Shams, S., Ahamad, A., Khan, S.A. and Anwar, F., 2015. Essential Oils Used in Aromatherapy: A Systemic Review. Asian Pacific Journal of Tropical Biomedicine. 5, Pp.601-611

Bresson, W., Borges, M.T. 2004. Delivery Methode for Introducing Endophitic Bacteria into Maize. Biocontrol. 49: Pp.315-322

Dugasani, S., Pichika, M.R., Nadarajah, V.D., Balijepalli, M.K., Tandra S. and Korlakunta, J.N.,2010. Comparative Antioxidant and Anti-Inflammatory Effects of [6]-Gingerol, [8]-Gingerol, [10]-Gingerol and [6]-Shogaol. Journal of Ethnopharmacology. 127, Pp.515-520.

Eldeen, I. M. S., Elgorashi, E. E., & van Staden, J. 2005. Antibacterial, antiinflammatory, anti-colinesterase and mutagenic effects of extracts obtained from some trees used in South African traditional medicine. Journal of Ethnopharmacology, 102, Pp.457–464.

Hertiani T., palupi I.S, Sanliferianti, dan Nurwindasari, H.D. 2003. Uji potensi Anti mikroba terhadap Staphylococcus aureus, E.coli, Shigella dysentri dan Candida albican dari Beberapa Tanaman Obat Tradisional untuk Penyakit Infeksi. Pharmacon vol.4 No. 2 UMS Surakarta.

Jeong, C.H., Bode, A.M., Pugliese, A., Cho, Y.Y., Kim, H.G., Shim, J.H., Jeon, Y.J.,Li, H., Jiang, H. and Dong, Z. 2009. [6]-Gingerol Suppresses Colon Cancer Growthby Targeting Leukotriene A4 Hydrolase. Cancer Research. 69, Pp. 5584-5591.

Kamazeri, T.S., Samah, O.A., Taher, M., Susanti, D. and Qaralleh, H. 2012. Antimicrobial Activity and Essential Oils of Curcuma aeruginosa, Curcuma mangga , and Zingiber cassumunar from Malaysia. Asian Pacific Journal of Tropical Medicine , 5, Pp.202-209.

López, E.I.C., Mariana F. H.B., Jenyffer M. R. M., Areli D. R. O., María T. O. M., Rocío, P. T. 2017. Antimicrobial Activity of Essential Oil of Zingiber officinale Roscoe (Zingiberaceae). American Journal of Plant Sciences. 8, Pp. 1511-1524

Mesomo, M.C., Corazza, M.L., Ndiaye, P.M., Dalla Santa, O.R., Cardozo, L. And Scheer, A.P. 2013. Supercritical CO2 Extracts and Essential Oil of Ginger (Zingiber officinale R.): Chemical Composition and Antibacterial Activity. The Journal of Supercritical Fluids. 80, Pp.44-49.

Sivasothy, Y., Chong, W.K., Hamid, A., Eldeen, I.M., Sulaiman, S.F. and Awang, K. 2011. Essential Oils of Zingiber officinale var. Rubrum Theilade and Their Antibacterial Activities. Food Chemistry. 124, Pp. 514-517.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2018 Journal Of Vocational Health Studies

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

This Journal is Indexed by: 

                 .


Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.