INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS

Firnanda Iptita Dewi; Manik retno Wahyunitisari

doi:10.20473/jvhs.V1.I3.2018.113-116

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Firnanda Iptita Dewi
firnandaiptitadewi@gmail.com
Student of Medical Analyst, Department of Health, Faculty of Vocational Education, Universitas Airlangga, Indonesia
Manik retno Wahyunitisari Department of Microbiology, Faculty of Medicine, Universitas Airlangga, Indonesia

Vol. 1 No. 3 (2018): March 2018 | JOURNAL OF VOCATIONAL HEALTH STUDIES

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Background: gram-negative bacteria-salmonella typhi and gram-positive bacteria-staphylococcus aureus are types of bacteria that cause infectious disease among several areas in Indonesia. Staphylococcus aureus often found in skin lesions injury. Red ginger extract (Zingiber officinale var rubrum) has been known for its medicinal value especially as an antibacterial agent. Purpose: This study aims to test the ability of Zingiber officinale var rubrum on inhibiting the growth of Staphylococcus aureus. Methods: the activity of the antibacterial agent was calculated based on Minimum Inhibitory Concentration (MIC) using dilution method. Minimum Inhibitory Concentration of extract was determined by incubating bacteria with the extract overnight at 37 ⁰C. Changes in turbidity and inhibition on bacterial growth were then observed. Result: The results show that minimum concentration for inhibitory effect was 1000 Î¼g/mL. Conclusion: extract of Zingiber officinale var rubrum have an inhibitory effect on the growth of Staphylococcus aureus but no activity of killing bacterial was observed on the concentration given.

Dewi, F. I., & Wahyunitisari, M. retno. (2018). INHIBITORY ACTIVITY OF ZINGIBER OFFICINALE VAR RUBRUM EXTRACT AGAINST STAPHYLOCOCCUS AUREUS. Journal of Vocational Health Studies, 1(3), 113–116. https://doi.org/10.20473/jvhs.V1.I3.2018.113-116

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Ali, B., Al-Wabel, N.A., Shams, S., Ahamad, A., Khan, S.A. and Anwar, F., 2015. Essential Oils Used in Aromatherapy: A Systemic Review. Asian Pacific Journal of Tropical Biomedicine. 5, Pp.601-611

Bresson, W., Borges, M.T. 2004. Delivery Methode for Introducing Endophitic Bacteria into Maize. Biocontrol. 49: Pp.315-322

Dugasani, S., Pichika, M.R., Nadarajah, V.D., Balijepalli, M.K., Tandra S. and Korlakunta, J.N.,2010. Comparative Antioxidant and Anti-Inflammatory Effects of [6]-Gingerol, [8]-Gingerol, [10]-Gingerol and [6]-Shogaol. Journal of Ethnopharmacology. 127, Pp.515-520.

Eldeen, I. M. S., Elgorashi, E. E., & van Staden, J. 2005. Antibacterial, antiinflammatory, anti-colinesterase and mutagenic effects of extracts obtained from some trees used in South African traditional medicine. Journal of Ethnopharmacology, 102, Pp.457–464.

Hertiani T., palupi I.S, Sanliferianti, dan Nurwindasari, H.D. 2003. Uji potensi Anti mikroba terhadap Staphylococcus aureus, E.coli, Shigella dysentri dan Candida albican dari Beberapa Tanaman Obat Tradisional untuk Penyakit Infeksi. Pharmacon vol.4 No. 2 UMS Surakarta.

Jeong, C.H., Bode, A.M., Pugliese, A., Cho, Y.Y., Kim, H.G., Shim, J.H., Jeon, Y.J.,Li, H., Jiang, H. and Dong, Z. 2009. [6]-Gingerol Suppresses Colon Cancer Growthby Targeting Leukotriene A4 Hydrolase. Cancer Research. 69, Pp. 5584-5591.

Kamazeri, T.S., Samah, O.A., Taher, M., Susanti, D. and Qaralleh, H. 2012. Antimicrobial Activity and Essential Oils of Curcuma aeruginosa, Curcuma mangga , and Zingiber cassumunar from Malaysia. Asian Pacific Journal of Tropical Medicine , 5, Pp.202-209.

López, E.I.C., Mariana F. H.B., Jenyffer M. R. M., Areli D. R. O., María T. O. M., Rocío, P. T. 2017. Antimicrobial Activity of Essential Oil of Zingiber officinale Roscoe (Zingiberaceae). American Journal of Plant Sciences. 8, Pp. 1511-1524

Mesomo, M.C., Corazza, M.L., Ndiaye, P.M., Dalla Santa, O.R., Cardozo, L. And Scheer, A.P. 2013. Supercritical CO2 Extracts and Essential Oil of Ginger (Zingiber officinale R.): Chemical Composition and Antibacterial Activity. The Journal of Supercritical Fluids. 80, Pp.44-49.

Sivasothy, Y., Chong, W.K., Hamid, A., Eldeen, I.M., Sulaiman, S.F. and Awang, K. 2011. Essential Oils of Zingiber officinale var. Rubrum Theilade and Their Antibacterial Activities. Food Chemistry. 124, Pp. 514-517.