Chemical Peeling in Skin-Aging Patients: A Retrospective Study
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Background: Skin aging is a degenerative process that involves a decrease in the structure and function of skin cells and the
extracellular matrix due to intrinsic and extrinsic factors. Chemical peeling is one of the skin aging treatments that involves
skin ablation using chemical agents. Purpose: To evaluate the profile of skin-aging patients treated with chemical peeling at
the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Hospital Surabaya from January through
December 2019. Methods: The data were obtained from patients' medical records through a total sampling technique, which
consisted of age, gender, occupation, history taking, physical examination, diagnosis, therapeutic agents, follow-up frequency,
and therapeutic result. Result: The study included 37 patients, the majority of whom were between the ages of 46 and 55
(35.1%), female (100%), and private employees (32.4%). In history taking, patients' main complaint is dull skin (94.6%), with
the risk factor of sun exposure (97.3%) and the history of sunscreen usage (81.1%). Pigmentary changes were found in all
patients (100%). The most common diagnoses are photoaging Glogau II and Glogau III, found in 15 patients (40.5%),
respectively. The common priming agents were sunscreen (97.3%), cleanser (94.6%), and 8% glycolic acid (75.7%). The
majority of patients (62.2%) received 20% glycolic acid as a peeling agent and sunscreen (86.5%) as a post-peeling agent.
The majority of patients (43.2%) did not follow up. Glogau II photoaging (57.1%) was the main therapeutic result.
Conclusion: Proper chemical peeling procedures and patients compliance are important factors to improve therapeutic
outcomes.
Zhang S, Duan E. Fighting against skin aging: the way from bench to bedside cell transplantation. Cell Transplant 2018;27(5):729–38.
Farage MA, Miller KW, Elsner P, Maibach HI. Characteristics of the aging skin. Adv Wound Care 2013; 2(1): 5–10.
Rahmadewi R, Retha R, Ayu Pitasari D, Adiningtyas Kusumastanto V, Anindita Ayu Ardhaninggar A, Citrashanty I, et al. The efficacy of amniotic membrane stem cell (AMSC) metabolite product and vitamin e for wrinkles, spots, and pores in photoaging. Dermatol Res Pract 2020; 1–5.
Rachmantyo B, Indramaya DM. Peeling asam glikolat pada pasien photoaging ( retrospective study : glycolic acid peel in photoaging patient ). BIKKK Kesehatan 2016; 28(1): 27–33.
Faghihi G, Fatemi-Tabaei S, Abtahi-Naeini B, Siadat AH, Sadeghian G, Ali Nilforoushzadeh M, et al. The effectiveness of a 5% retinoic acid peel combined with microdermabrasion for facial photoaging: a randomized, double-blind, placebo-controlled clinical trial. Dermatol Res Pract 2017; 2017: 1–6.
Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: a key molecule in skin aging. Dermato-Endocrinology 2012; 4(3): 253–8.
A. Farage, M. Gender differences in skin aging and the changing profile of the sex hormones with age. J Steroids Horm Sci 2012; 03(02): 1–10.
Ahmad Z, Damayanti. Penuaan kulit : patofisiologi dan manifestasi klinis ( skin aging : pathophysiology and clinical manifestation). BIKKK 2018; 30(3): 208–15.
Yonei Y, Takabe W, Yagi M. Photoaging and glycation of elastin : effect on skin. Glycative Stress Research 2015; 2(1): 182–90.
Putri WE, Endaryanto A, Tinduh D, Rantam F, Notobroto HB, Rosita C, et al. Skin barrier before and after topical adipose stem cell-conditioned medium (ASC-CM) treatment in photoaging. Bali Medical Journal 2021; 10(2): 688–91.
Sutaria AH, Masood S, Schlessinger J. Acne vulgaris (FL). StatPearls Publishing 2021.
Kang HY, Lee JW, Papaccio F, Bellei B, Picardo M. Alterations of the pigmentation system in the aging process. Pigment Cell Melanoma Res 2021; 34(4): 800–13.
Parrado C, Mercado-Saenz S, Perez-Davo A, Gilaberte Y, Gonzalez S, Juarranz A. Environmental stressors on skin aging. mechanistic insights. Front Pharmacol 2019; 10: 759.
Ding A, Yang Y, Zhao Z, Hüls A, Vierkötter A, Yuan Z, et al. Indoor PM2.5 exposure affects skin aging manifestation in a chinese population. Scientific Reports 2017; 7(1): 1–7.
Bocheva GS, Slominski RM, Slominski AT. Immunological aspects of skin aging in atopic dermatitis. Int J Mol Med Sci 2021; 22(11): 5729.
Liu T, Li N, Yan Y qi, Liu Y, Xiong K, Liu Y, et al. Recent advances in the anti"aging effects of phytoestrogens on collagen, water content, and oxidative stress. Phytother Res 2020; 34(3): 435.
Gabros S, Nessel TA, Zito PM. Sunscreens and photoprotection (FL). StatPearls Publishing 2021.
Yang Z, Zhang Y, Lazic Mosler E, Hu J, Li H, Zhang Y, et al. Topical benzoyl peroxide for acne. Cochrane Database Syst Rev 2020; 2020(3).
Ganceviciene R, Liakou AI, Theodoridis A, Makrantonaki E, Zouboulis CC. Skin anti-aging strategies. DermatoendocrinolTaylor & Francis 2012; 4(3): 308–19.
Rittié L, Fisher GJ. Natural and sun-induced aging of human skin. Cold Spring Harb Perspect Med 2015; 5(1).
O'Connor AA, Lowe PM, Shumack S, Lim AC. Chemical peels: a review of current practice. Australas J Dermatol 2018; 59(3): 171–81.
Truchuelo M, Cerdá P, Fernández LF. Chemical peeling: a useful tool in the office. Vol. 108, Actas Dermo-Sifiliográficas (English Edition) 2017; 108(4): 315–22.
Nikalji N, Godse K, Sakhiya J, Patil S, Nadkarni N. Complications of medium depth and deep chemical peels. J Cutan Aesthet Surg 2012; 5(4): 254–60.
Fischer TC, Perosino E, Poli F, Viera MS, Dreno B. Chemical peels in aesthetic dermatology: an update 2009. J Eur Acad Dermatol Venereol 2010; 24(3): 281–92.
Lin J, Sklar GE, Oh VM Sen, Li SC. Factors affecting therapeutic compliance: A review from the patient's perspective. Ther Clin Risk Manag 2008;4(1): 269–86.
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