FORMULATION AND EVALUATION OF SEA GRAPE (Caulerpa racemose) EXTRACT AS HAND CREAM AND ITS ANTIOXIDANT ACTIVITY TEST
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Caulerpa racemosa (C. racemosa) is a seaweed containing folic acid, thiamine, ascorbic acid, and phenol as secondary metabolites that function as antioxidants. This study aims to formulate a hand moisturizing cream containing C. racemosa extract and evaluate the quality of the cream preparation. The manufacture of hand cream from C. racemosa extract was carried out in several stages, namely C. racemosa extraction, antioxidant testing, formulation of cream preparations, and evaluation. Evaluation of hand cream preparations of C. racemosa extract included organoleptic tests, homogeneity, pH measurement, viscosity, spreadability, and adhesion. The yield of C. racemosa from the extract was 33%. The IC50 of the C. racemosa extract was 159.8 ppm. The results of the organoleptic test of hand cream preparations showed physical characteristics in terms of pH, viscosity, homogeneity, dispersibility, and adhesion following the requirements of cosmetic preparations from the Directorate General of BPOM.
Allen LV., 1999, Compounding Creams and Lotions, Int J Pharm Compd, 3(2):111-115. PMID: 23985554.
Allen LV., 2002. The Art, Science, and Technology of Pharmaceutical Compounding, Second Edition, American Pharmaceutical Association, Washington, D.C; 291-296
Anief M. 2000. Ilmu Meracik Obat, Teori dan Praktek, Gajah Mada University Press, Yogyakarta; 168-169.
Anwar LO, Bubun RL, & Rosmawati, 2016, Manfaat Anggur Laut (Caulerpa racemosa) dan Penanganannya dengan Melibatkan Masyarakat Pantai di Desa Rumba-Rumba, Seminar Nasional dan Gelar Produk yang diselenggarakan oleh Universitas Muhammadiyah Malang.
Aulton ME, 1991, Pharmaceutical Practice, Longman Singapore Publisher Ptc Ltd, Singapore.
Azkiya Z, Ariyani H, & Nugraha TS, 2017, Evaluasi sifat fisik krim ekstrak jahe merah (Zingiber officinale Rosc. var. rubrum) sebagai anti nyeri, JCPS (Journal of Current Pharmaceutical Sciences), 1(1): 12-18.
Chew YL, Lim YY, Omar M, & Khoo KS, 2008, Antioxidant activity of three edible seaweeds from two areas in South East Asia, LWT-Food Science and Technology, 41(6): 1067-1072.
Engelin, 2013, Optimasi Krim Sarang Burung Walet Putih Tipe M/A Dengan Variasi Emulgator Sebagai Pencerah Kulit Menggunakan Simplex Lattice Design, Fakultas Kedokteran, Universitas Tanjungpura Pontianak.
Ghozali I, 2016, Aplikasi Analisis Multivariete Dengan Program IBM SPSS 23, Edisi 8, Badan Penerbit Universitas Diponegoro, Semarang.
Khopkar SM, 1990, Konsep Dasar Kimia Analitik, UI Press, Jakarta.
Lubis ES, & Reveny J, 2012, Pelembab Kulit Alami Dari Sari Buah Jeruk Bali [Citrus maxima (Burm.) Osbeck], Journal of Pharmaceutics and Pharmacology, 1(2): pp.104–111.
Marraskuranto, E., Nursid, M., Utami, S., Setyaningsih, I. and Tarman, K., 2021, Kandungan Fitokimia, Potensi Antibakteri dan Antioksidan Hasil Ekstraksi Caulerpa racemosa dengan Pelarut Berbeda. Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 16(1), pp.1-10.
Molyneux P, 2004, The use of the stable free radical diphenylpicryl-hydrazyl (DPPH) for estimating antioxidant activity. Songklanakarin Journal of Science Technology,
Muchtadi TR, & Sugiyono, 1992, Petunjuk Laboratorium Ilmu Pengetahuan Bahan Pangan, Pusat Antar Universitas Pangan dan Gizi IPB, Bogor.
Redaksi Agrozine, 2020, Mengenal Tanaman Anggur Laut Lawi-Lawi dan Ragam Khasiatnya. www.Agrozine.id. Retrieved January 14.2021
Rowe RC, Sheskey PJ, & Owen SC, 2006, Handbook of Pharmaceutical Excipients, Fifth Edition, Pharmaceutical Press, London: 110-114,441-443, 445, 522-524, 549-553, 752-755.
Santoso J, Gunji S, Yoshie-Stark Y, & Suzuki T, 2006, Mineral contents of Indonesian seaweeds and mineral solubility affected by basic cooking, Food Science and Technology Research, 12(1):59-66.
SNI 16-4399, 1996, Sediaan Tabir Surya,Badan Standardisasi Nasional.
Soebagio B, Sriwododo, & Adhika AS, 2009, Uji Sifat Fisikokimia Pati Biji Durian (Durio Zibethinus Murr) Alami Dan Modifikasi Secara Hidrolisis Asam, Universitas Padjajaran, Bandung.
Sudijono A, 2010, Pengantar Statistik Pendidikan, Rajawali Press, Jakarta.
Suhartini S, 2003, Penapisan awal Caulerpa racemosa, Sesuvium portulacastrum, Xylocarpus granatum dan Ulva lactuca Sebagai Antimikroba, Institut Pertanian Bogor
Sundari, H, 2012, Formulasi Sediaan Krim Cair Tangan dan Badan Menggunakan Sari Kacang Kedelai (Soya max L) Sebagai Bahan Pelembab, Universitas Sumatera Utara.
Tarwendah IP, 2017, Jurnal Review: Studi Komparasi Atribut Sensoris dan Kesadaran Merek Produk Pangan, Jurnal Pangan dan Agroindustri, 5(2): 66-73
Tumbelaka, Riddel MMY, Momuat, Lidya I, & Wuntu AD, 2019, Pemanfaatan VCO Mengandung Karotenoid Tomat dan Karagenan dalam Pembuatan Lotion, Pharmacon, 8(1): 94–105.
Wirantara Y, 2011, Optimasi Proses Pencampuran Hand Krim dengan Kajian Kecepatan Putar Mixer, Waktu dan Suhu Pencampuran Menggunakan Metode Desain Faktorial, Universitas Sanata Dharma.
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