Chicken Oil as The New Cooking Oil : Its Effect on Lipid Profile and Liver Histology in Male Wistar Rats
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ABSTRACT
Background: The selection of the appropriate cooking oil by society will reduce high fat intake. Chicken oil as a new cooking oil that is starting to be used by some people as a substitute for palm oil, needs to be studied for its health effects.Objectives: This study aimed to see and compare changes in lipid profiles and liver histology in male Wistar rats fed with chicken oil and palm oil.Methods: Male Wistar rats (n = 10) were separated into two groups randomly, namely the chicken oil group and the palm oil group. Each rat in the group was given oil at a dose of 1 mL/day. Before treatment, lipid profile levels were measured, and after four weeks of treatment, lipid profile levels and liver histology were examined.Results: Administration of 1 mL/day of oil in each group for four weeks diminished total cholesterol, HDL, LDL levels at the two groups also increased triglyceride levels in the two groups, but non-significant differences among groups. This research also showed the formation of hepatic steatosis in all groups, but still mild-moderate microvesicular steatosis, and non-significant differences among groups.Conclusion: The consumption of 1 mL/day of chicken oil for four weeks has a similar effect on lipid profiles and liver histology as the consumption of 1 mL/day of palm oil with the same duration. We propose further study by administering the intervention of chicken oil to rats for a longer time.
Misra, A., Singhal, N. & Khurana, L. Obesity, the metabolic syndrome, and type 2 diabetes in developing countries: Role of dietary fats and oils. J. Am. Coll. Nutr. 29, 289S-301S (2010).
Surasa, N. J., Utami, N. R. & Isnaeni, W. Struktur Mikroanatomi Hati dan Kadar Kolesterol Total Plasma Darah Tikus Putih Strain Wistar Pasca Suplementasi Minyak Lemuru dan Minyak Sawit. Biosaintifika J. Biol. Biol. Educ. 6, 117–127 (2014).
Van Der Wulp, M. Y. M., Verkade, H. J. & Groen, A. K. Regulation of cholesterol homeostasis. Mol. Cell. Endocrinol. 368, 1–16 (2013).
Sa'Adah, N. N., Purwani, K. I., Nurhayati, A. P. D. & Ashuri, N. M. Analysis of lipid profile and atherogenic index in hyperlipidemic rat (Rattus norvegicus Berkenhout, 1769) that given the methanolic extract of Parijoto (Medinilla speciosa). AIP Conf. Proc. 1854, (2017).
Hardinsyah. Analisis Konsumsi Lemak, Gula Dan Garam Penduduk. Gizi Indones. 34, 92–100 (2011).
Muharam Nurdin, N., Anna Marliyati, S., Martianto, D. & Subangkit, M. Akumulasi lipid hati dan profil lipid darah tikus Sprague Dawley yang diintervensi minyak super olein dan olein. J. Gizi dan Pangan 11, 67–74 (2016). Available from : http://journal.ipb.ac.id/index.php/jgizipangan/article/view/13171/9923
Reagan-Shaw, S., Nihal, M. & Ahmad, N. Dose translation from animal to human studies revisited. FASEB J. 22, 659–661 (2008).
Méndez-Lagunas, L. L., Siles-Alvarado, S., Rodríguez-Ramírez, J. & Aquino-González, L. A. Fatty Acid Profile Composition of Chicken Skin. Int. J. Chem. Biomol. Sci. 1, 193–196 (2015).
Bowen, K. J. et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J. Nutr. 149, 471–478 (2019).
Duavy, S. M. P., Salazar, G. J. T., Leite, G. de O., Ecker, A. & Barbosa, N. V. Effect of dietary supplementation with olive and sunflower oils on lipid profile and liver histology in rats fed high cholesterol diet. Asian Pac. J. Trop. Med. 10, 539–543 (2017).
Ong, A. S. H. & Goh, S. H. Palm oil: A healthful and cost-effective dietary component. Food Nutr. Bull. 23, 11–22 (2002).
Mancini, A. et al. Biological and nutritional properties of palm oil and palmitic acid: Effects on health. Molecules 20, 17339–17361 (2015).
Stonehouse, W., Benassi-Evans, B., James-Martin, G. & Abeywardena, M. Fatty acid regio-specificity of triacylglycerol molecules may affect plasma lipid responses to dietary fats”a randomised controlled cross-over trial. Eur. J. Clin. Nutr. 74, 268–277 (2020).
Sambanthamurthi, R., Sundram, K. & Tan, Y. A. Chemistry and biochemistry of palm oil. Progress in Lipid Research vol. 39 (2000).
Tchernof, A. & Després, J. P. Pathophysiology of human visceral obesity: An update. Physiol. Rev. 93, 359–404 (2013).
Ferramosca, A., Savy, V. & Zara, V. Olive oil increases the hepatic triacylglycerol content in mice by a distinct influence on the synthesis and oxidation of fatty acids. Biosci. Biotechnol. Biochem. 72, 62–69 (2008).
Nassir, F., Rector, R. S., Hammoud, G. M. & Ibdah, J. A. Pathogenesis and prevention of hepatic steatosis. Gastroenterol. Hepatol. 11, 167–175 (2015).
Tandra, S. et al. Presence and significance of microvesicular steatosis in nonalcoholic fatty liver disease. J. Hepatol. 55, 654–659 (2011).
Manne, V., Handa, P. & Kowdley, K. V. Pathophysiology of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis. Clin. Liver Dis. 22, 23–37 (2018).
Tomizawa, M. et al. Triglyceride is strongly associated with nonalcoholic fatty liver disease among markers of hyperlipidemia and diabetes. Biomed. Reports 2, 633–636 (2014).
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