COMPARATIVE STUDY OF TIME ECHO VARIATIONS IN THE METABOLITE VALUES MR BRAIN SPECTROSCOPY

Revina  Dewi Susanto; Ayu  Yuliana F.; Eunike  Serfina F.; Celine  Catharina R.; Merry Amnesti; Siti Masrochah; Lina  Choridah

doi:10.20473/jvhs.V8.I1.2024.7-14

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Revina Dewi Susanto
revinadewis.07@gmail.com
Radiologic Imaging Technology, Department of Health, Faculty of Vocational Study, Universitas Airlangga, Indonesia, Indonesia https://orcid.org/0009-0002-1264-7410
Ayu Yuliana F. Magister Applied Imaging Diagnostic, Health Polytechnic of Semarang, Indonesia, Indonesia https://orcid.org/0009-0000-0291-3645
Eunike Serfina F. MRI Application Specialist, GE Healthcare, Indonesia, Indonesia https://orcid.org/0000-0001-8283-8824
Celine Catharina R. Uppsala University, Faculty of Medicine, Department of Genetic, Immunology and Pathology, Uppsala, Sweden, Sweden https://orcid.org/0000-0001-8862-6734
Merry Amnesti Radiologic Technologist, Mayapada Hospital, Radiology Department, Indonesia, Indonesia https://orcid.org/0009-0009-7502-3569
Siti Masrochah Magister Applied Imaging Diagnostic, Health Polytechnic of Semarang, Indonesia, Indonesia https://orcid.org/0009-0002-9542-7244
Lina Choridah Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Indonesia, Indonesia https://orcid.org/0000-0002-0917-9372

Vol. 8 No. 1 (2024): July 2024 | JOURNAL OF VOCATIONAL HEALTH STUDIES

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Background: MR spectroscopy is an additional sequence to evaluate lesion characteristics in the brain. Time Echo (TE) is crucial for analyzing MR spectroscopy metabolite. Purpose: This study aims to evaluate the best TE variations during MR spectroscopy examinations in brain lesions. Method: This research is an experimental quantitative study. Researchers used five samples focusing on the results of head multi-voxel spectroscopy charts with clinical lesions or masses that had been taken twice using TE 35 and TE 144. At each TE in each sample, three voxel areas were measured, namely normal, perilesional, and lesion. Each spectroscopy data result is processed individually through READY View software, automatically producing a spectroscopy graph pattern. The required data in this study is the value of each head spectroscopy metabolism: N-Acetyl Aspartate (NAA), Choline (Cho), Creatine (Cr), Myo-Inositol (MI), Lipids Lactate (LL). All statistical tests used the SPSS v.26 application. Result: Based on Paired T test results, NAA, Cho, Cr, and MI metabolites have p-values that account for 0.779 > 0.05; 0.179 > 0.05; 0.581 > 0.05; and 0.057 > 0.05. Based on the Wilcoxon Sign Rank test, the LL metabolite showed a p-value of 0.460 > 0.05. Conclusion: There is no significant difference between TE 35 ms and TE 144 ms during MR spectroscopy examinations.

Dewi Susanto, R. ., Yuliana F., A. ., Serfina F., E. ., Catharina R., C. ., Amnesti, M., Masrochah , S., & Choridah, L. . (2024). COMPARATIVE STUDY OF TIME ECHO VARIATIONS IN THE METABOLITE VALUES MR BRAIN SPECTROSCOPY. Journal of Vocational Health Studies, 8(1), 7–14. https://doi.org/10.20473/jvhs.V8.I1.2024.7-14

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