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Association between Glycemic Index (GI), Glycemic Load (GL), and Dietary Inflammatory Index (DII) with Metabolic Syndrome in Young Adult Women with Obesity in Semarang Indonesia

glycemix index Glycemic Load metabolic syndrome obesity dietary inflammatory index

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Background: Dietary choice plays an important role in the incidence of metabolic syndrome in young adult women. Consuming foods that follow current trends has insulinogenic and inflammatory effects.

Objectives: Analysis of the relationship between the Glycemic Index (GI), Glycemic Load (GL), and Dietary Inflammatory Index (DII) and the incidence of metabolic syndrome in obese women in Semarang

Methods: This research was carried out at a time when there were restrictions on community activities due to the COVID-19 pandemic. The sampling technique was consecutive sampling and cross-sectional design. The subjects in this study were 126 people with the characteristics of abdominally obese women (LP > 80cm) aged 19–25 years in the Semarang City area of Indonesia. Intake conversion guidelines use the International Table of Glycemic Index and the overall inflammatory effect score.

Results: A total of 11.9% of subjects experienced SM. The mean daily GI intake was 176.7±44.4 and GL was 458.4±183.3. The mean DII score was 28.76 ± 267.7 with a history of subject intake with a pro-inflammatory score of 71.4% and 28.6% anti-inflammatory. The relationship test resulted in the highest proportion of SM on the GI diet being 21.4% (p = 0.066). Meanwhile, the highest GL diet was 16.7% (p = 0.207). Subjects with SM status had an anti-inflammatory diet profile of 16.7% and a pro-inflammatory diet profile of 10% (p = 0.362). Meanwhile, the test of the relationship between diet profile and SM parameters resulted in the highest GI diet being 40.5% with high TG (p = 0.008), the highest GL diet being 59.5% with low HDL-C (p = 0.009), the DII diet being high GDP (p = 0.022), and the high DII diet being 47.8% with low HDL-C (p = 0.078). The test results for differences in GI and GL profiles between pro-inflammatory and anti-inflammatory diets were p = 0.295 and p = 0.483.

Conclusions: There is a borderline significant relationship between the dietary GI profile and the incidence of SM. Meanwhile, with SM parameters, there is a relationship between the GI diet profile and the incidence of TG, the GL diet

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