Nutritional Management and Recommendation for Preterm Infants: A Narrative Review
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Blencowe H et al. National, regional and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet 379, 2162–72 (2012).
Howson, C. P., Kinney, M. V, McDougall, L., Lawn, J. E. & Born Too Soon Preterm Birth Action Group. Born Too Soon: Preterm birth matters. Reprod. Health 10, 1–9 (2013).
Woythaler, M. A., McCormick, M. C. & Smith, V. C. Late preterm infants have worse 24-month neurodevelopmental outcomes than term infants. Pediatrics 127, (2011).
Liu, L. et al. Global, regional, and national causes of child mortality: An updated systematic analysis for 2010 with time trends since 2000. Lancet 379, 2151–2161 (2012).
The World Health Organization. WHO recommendations on interventions to improve preterm birth outcomes. (2015).
The World Health Organization. Preterm birth. World Health Organization Fact Sheets https://www.who.int/news-room/fact-sheets/detail/preterm-birth (2018).
Risnes, K. R. et al. Birthweight and mortality in adulthood: A systematic review and meta-analysis. Int. J. Epidemiol. 40, 647–661 (2011).
Wagura, P., Wasunna, A., Laving, A., Wamalwa, D. & Ng'ang'a, P. Prevalence and factors associated with preterm birth at kenyatta national hospital. BMC Pregnancy Childbirth 18, 107 (2018).
Yamashita, M. et al. Incidence and risk factors for recurrent spontaneous preterm birth: A retrospective cohort study in Japan. J. Obstet. Gynaecol. Res. 41, 1708–1714 (2015).
Spong, C. Y. Defining ‘term' pregnancy: Recommendations from the defining ‘term' pregnancy workgroup. JAMA - J. Am. Med. Assoc. 309, 2445–2446 (2013).
Naghavi-Behzad, M., Ghojazadeh, M., Mirnia, K., Azami-Aghdash, S. & Piri, R. Contributing death factors in very low-birth-weight infants by path method analysis. Niger. Med. J. 55, 389 (2014).
Eshete, A., Alemu, A. & Zerfu, T. A. Magnitude and Risk of Dying among Low Birth Weight Neonates in Rural Ethiopia: A Community-Based Cross-Sectional Study. Int. J. Pediatr. 2019, 1–8 (2019).
Suparmi, S., Chiera, B. & Pradono, J. Low birth weights and risk of neonatal mortality in Indonesia. Heal. Sci. J. Indones. 7, (2016).
The World Health Organization. Global Nutrition Targets 2025: Low birth weight policy brief. (2014).
Lee, K. A., Hayes, B. C. & Lee, K. A. Head size and growth in the very preterm infant: a literature review. Res. Reports Neonatol. 5, 1–7 (2015).
Tremblay, G. et al. Body Composition in Very Preterm Infants: Role of Neonatal Characteristics and Nutrition in Achieving Growth Similar to Term Infants. Neonatology 111, 214–221 (2017).
Solopova, I. A. et al. Muscle responses to passive joint movements in infants during the first year of life. Front. Physiol. 10, (2019).
Ince, D. A. et al. Evaluation of Moro reflex with objective method in late preterm and term infants. Early Hum. Dev. 129, 60–64 (2019).
Mayerl, C. J. et al. Sucking versus swallowing coordination, integration, and performance in preterm and term infants. J. Appl. Physiol. 129, 1383–1392 (2020).
Horne, R. S. C. et al. Comparison of the longitudinal effects of persistent periodic breathing and apnoea on cerebral oxygenation in term- and preterm-born infants. J. Physiol. 596, 6021–6031 (2018).
Lindström, L. et al. Growth patterns during early childhood in children born small for gestational age and moderate preterm. Sci. Rep. 9, (2019).
De Wit, C. C., Sas, T. C. J., Wit, J. M. & Cutfield, W. S. Patterns of catch-up growth. World Rev. Nutr. Diet. 109, 89–90 (2014).
Cheong, J. L. et al. Association between moderate and late preterm birth and neurodevelopment and social-emotional development at age 2 years. JAMA Pediatr. 171, (2017).
Shah, P., Kaciroti, N., Richards, B., Oh, W. & Lumeng, J. C. Developmental outcomes of late preterm infants from infancy to kindergarten. Pediatrics 138, (2016).
Grisaru-Granovsky, S. et al. Mortality and morbidity in preterm small-for-gestational-age infants: a population-based study. Am. J. Obstet. Gynecol. 206, 150.e1-150.e7 (2012).
Knobel, R. B. Fetal and neonatal thermal physiology. Newborn Infant Nurs. Rev. 14, 45–49 (2014).
Laptook, A. R. et al. Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants. J. Pediatr. 192, 53-59.e2 (2018).
Al Yazidi, G., Srour, M. & Wintermark, P. Risk Factors for Intraventricular Hemorrhage in Term Asphyxiated Newborns Treated With Hypothermia. Pediatr. Neurol. 50, 630–5 (2014).
De Almeida, M. F. B. et al. Hypothermia and early neonatal mortality in preterm infants. J. Pediatr. 164, (2014).
Wilson, E. et al. Admission Hypothermia in Very Preterm Infants and Neonatal Mortality and Morbidity. J. Pediatr. 175, 61-67.e4 (2016).
Yadav, S., Lee, B. & Kamity, R. Neonatal Respiratory Distress Syndrome. in StatPearls (StatPearls Publishing, 2021).
Huang, Y. et al. Neonatal outcome of small for gestational age infants born at 26–33 weeks' gestation in Chinese neonatal intensive care units. Transl. Pediatr. 10, 754–764 (2021).
Kim, D. H. et al. Risk factors for pulmonary artery hypertension in preterm infants with moderate or severe bronchopulmonary dysplasia. Neonatology 101, 40–46 (2011).
Eichenwald, E. C. & Committee on Fetus and Newborn. Apnea of Prematurity. Pediatrics 137, e20153757 (2016).
Godin, R., Carlos Rodriguez, J. & Kahn, D. J. Oral versus intravenous medications for treatment of patent ductus arteriosus in preterm neonates: A cost-saving initiative. J. Pediatr. Pharmacol. Ther. 26, 291–299 (2021).
Faust, K. et al. Short-term outcome of very-low-birthweight infants with arterial hypotension in the first 24 h of life. Arch. Dis. Child. Fetal Neonatal Ed. 100, F388–F392 (2015).
Özek, E. & Kersin, S. G. Intraventricular hemorrhage in preterm babies. Turk Pediatr. Ars. 55, 215–221 (2020).
Neu, J. & Walker, W. A. Necrotizing enterocolitis. N. Engl. J. Med. 364, 255–64 (2011).
Yee, W. H. et al. Incidence and Timing of Presentation of Necrotizing Enterocolitis in Preterm Infants. Pediatrics 129, e298-304 (2012).
Pike, K. et al. Outcomes at 7 years for babies who developed neonatal necrotising enterocolitis: The ORACLE Children Study. Arch. Dis. Child. Fetal Neonatal Ed. 97, F318-322 (2012).
Hickey, M., Georgieff, M. & Ramel, S. Neurodevelopmental outcomes following necrotizing enterocolitis. Semin. Fetal Neonatal Med. 23, 426–432 (2018).
Niemarkt, H. J. et al. Necrotizing enterocolitis: A clinical review on diagnostic biomarkers and the role of the intestinal microbiota. Inflamm. Bowel Dis. 21, 436–444 (2015).
Neu, J. & Pammi, M. Necrotizing enterocolitis: The intestinal microbiome, metabolome and inflammatory mediators. Semin. Fetal Neonatal Med. 23, 400–405 (2018).
Carlisle, E. & Morowitz, M. The intestinal microbiome and necrotizing enterocolitis. Curr Opin Pediatr 25, 382–387 (2013).
Tirone, C. et al. Gut and Lung Microbiota in Preterm Infants: Immunological Modulation and Implication in Neonatal Outcomes. Front. Immunol. 10, 2910 (2019).
Mccarthy, R. et al. Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis. Microbiome 5, 1–15 (2017).
Ramani, M. & N. Ambalavanan. Feeding Practices and NEC. Clin. Perinatol. 40, 1–10 (2013).
Hay Jr, W. W. Aggressive Nutrition of the Preterm Infant. Curr. Pediatr. Rep. 1, 229–39 (2013).
Collins, A., Weitkamp, J.-H. & Wynnc, J. L. Why are preterm newborns at increased risk of infection? Arch. Dis. Child. - Fetal Neonatal Ed. 103, F391–F394 (2018).
Melville, J. M. & Moss, T. J. M. The immune consequences of preterm birth. Front. Neurosci. 21, 79 (2013).
Singh, M., Alsaleem, M. & Gray, C. P. Neonatal Sepsis. in StatPearls (StatPearls Publishing, 2021).
Cai, S., Thompson, D. K., Anderson, P. J. & Yang, J. Y.-M. Short- and Long-Term Neurodevelopmental Outcomes of Very Preterm Infants with Neonatal Sepsis: A Systematic Review and Meta-Analysis. Children 6, 131 (2019).
Kim, S. J. et al. Retinopathy of prematurity: a review of risk factors and their clinical significance. Surv. Ophthalmol. 63, 618–637 (2018).
Ju, R. H. et al. Spontaneous regression of retinopathy of prematurity: Incidence and predictive factors. Int. J. Ophthalmol. 6, 475–480 (2013).
Bhutani, V. K., Wong, R. J. & Stevenson, D. K. Hyperbilirubinemia in Preterm Neonates. Clin. Perinatol. 43, 215–232 (2016).
Andersen, C. C., Keir, A. K., Kirpalani, H. M. & Stark, M. J. Anaemia in the Premature Infant and Red Blood Cell Transfusion: New Approaches to an Age-Old Problem. Curr. Treat. Options Pediatr. 1, 191–201 (2015).
Sharma, A., Davis, A. & Shekhawat, P. S. Hypoglycemia in the preterm neonate: Etiopathogenesis, diagnosis, management and long-term outcomes. Transl. Pediatr. 6, 335–340 (2017).
Abramowski, A., Ward, R. & Hamdan, A. H. Neonatal Hypoglycemia. in StatPearls (StatPearls Publishing, 2021).
Ehrenkranz, R. A. Extrauterine growth restriction: Is it preventable? J. Pediatr. (Rio. J). 90, 1–3 (2014).
Peila, C. et al. Extrauterine growth restriction: Definitions and predictability of outcomes in a cohort of very low birth weight infants or preterm neonates. Nutrients 12, (2020).
Boyle, E. M. et al. Effects of gestational age at birth on health outcomes at 3 and 5 years of age: Population based cohort study. BMJ 344, (2012).
Stephens, A. S., Lain, S. J., Roberts, C. L., Bowen, J. R. & Nassar, N. Survival, Hospitalization, and Acute-Care Costs of Very and Moderate Preterm Infants in the First 6 Years of Life: A Population-Based Study. J. Pediatr. 169, 61-68e3 (2016).
Kuint, J. et al. Rehospitalization Through Childhood and Adolescence: Association with Neonatal Morbidities in Infants of Very Low Birth Weight. J. Pediatr. 188, 135-141.e2 (2017).
Woythaler, M. A., McCormick, M. C. & Smith, V. C. Late preterm infants have worse 24-month neurodevelopmental outcomes than term infants. Pediatrics 127, e622–9 (2011).
Patel, R. M. Short- and Long-Term Outcomes for Extremely Preterm Infants. Am. J. Perinatol. 33, 318–328 (2016).
Hack, M. et al. Change in prevalence of chronic conditions between childhood and adolescence among extremely low-birth-weight children. J. Am. Med. Assoc. 306, 394–401 (2011).
Holsti, A., Adamsson, M., Hagglof, B., Farooqi, A. & Serenius, F. Chronic conditions and health care needs of adolescents born at 23 to 25 weeks' gestation. Pediatrics 139, (2017).
Morrison, K. M. et al. Cardiometabolic health in adults born premature with extremely low birth weight. Pediatrics 138, (2016).
Sipola-Leppänen, M. et al. Ambulatory blood pressure and its variability in adults born preterm. Hypertension 65, 615–621 (2015).
Groer, M. W. et al. Development of the preterm infant gut microbiome: A research priority. Microbiome 2, 38 (2014).
Younge, N. E. et al. Disrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure. Sci. Rep. 9, 8167 (2019).
Henderickx, J. G. E., Zwittink, R. D., Van Lingen, R. A., Knol, J. & Belzer, C. The preterm gut microbiota: An inconspicuous challenge in nutritional neonatal care. Front. Cell. Infect. Microbiol. 9, 85 (2019).
Robertson, R. C., Manges, A. R., Finlay, B. B. & Prendergast, A. J. The Human Microbiome and Child Growth – First 1000 Days and Beyond. Trends Microbiol. 27, 131–147 (2019).
Hay, W. W. Optimizing nutrition of the preterm infant. Chinese J. Contemp. Pediatr. 19, 1–21 (2017).
Charbonneau, M. R. et al. A microbial perspective of human developmental biology. Nature 535, 48–55 (2016).
Fanaro, S. Feeding intolerance in the preterm infant. Early Hum. Dev. 89, 513–20 (2013).
Goedicke-Fritz, S. et al. Preterm birth affects the risk of developing immune-mediated diseases. Front. Immunol. 8, 1266 (2017).
Tamburini, S., Shen, N., Wu, H. C. & Clemente, J. C. The microbiome in early life: Implications for health outcomes. Nat. Med. 22, 713–722 (2016).
Rodríguez, J. M. et al. The composition of the gut microbiota throughout life, with an emphasis on early life. Microb. Ecol. Heal. Dis. 26, 26050 (2015).
Hay, W. W. Nutritional support strategies for the preterm infant in the neonatal intensive care unit. Pediatr. Gastroenterol. Hepatol. Nutr. 21, 234–247 (2018).
Hanson, C., Sundermeier, J., Dugick, L., Lyden, E. & Anderson-Berry, A. L. A. L. Implementation, process, and outcomes of nutrition best practices for infants <1500 g. Nutr. Clin. Pract. 26, 614–624 (2011).
Vinall, J. et al. Slower postnatal growth is associated with delayed cerebral cortical maturation in preterm newborns. Sci. Transl. Med. 5, 168ra8 (2013).
Shim, S. Y., Ahn, H. M., Cho, S. J. & Park, E. A. Early aggressive nutrition enhances language development in very low-birthweight infants. Pediatr. Int. 56, 845–850 (2014).
Eleni dit Trolli, S., Kermorvant-Duchemin, E., Huon, C., Bremond-Gignac, D. & Lapillonne, A. Early lipid supply and neurological development at one year in very low birth weight (VLBW) preterm infants. Early Hum. Dev. 88, S25-29 (2012).
Duerden, E. G. et al. Early protein intake predicts functional connectivity and neurocognition in preterm born children. Sci. Rep. 11, (2021).
Lewis, E. D., Richard, C., Larsen, B. M. & Field, C. J. The Importance of Human Milk for Immunity in Preterm Infants. Clin. Perinatol. 44, 23–47 (2017).
Moukarzel, S. & Bode, L. Human Milk Oligosaccharides and the Preterm Infant: A Journey in Sickness and in Health. Clin. Perinatol. 44, 193–207 (2017).
Neerven, R. J. J. van & Savelkoul, H. Nutrition and Allergic Diseases. Nutrients 9, 762 (2017).
Horta, B. L., Loret De Mola, C. & Victora, C. G. Long-term consequences of breastfeeding on cholesterol, obesity, systolic blood pressure and type 2 diabetes: A systematic review and meta-analysis. Acta Paediatr. Int. J. Paediatr. 104, 30–37 (2015).
Andreas, N. J., Kampmann, B. & Le-Doare, K. M. Human breast milk: A review on its composition and bioactivity. Early Hum. Dev. 91, 629–635 (2015).
Turfkruyer, M. & Verhasselt, V. Breast milk and its impact on maturation of the neonatal immune system. Curr. Opin. Infect. Dis. 28, 199–206 (2015).
Plaza-Díaz, J., Fontana, L. & Gil, A. Human milk oligosaccharides and immune system development. Nutrients 10, (2018).
Donovan, S. M. & Comstock, S. S. Human milk oligosaccharides influence neonatal mucosal and systemic immunity. Ann. Nutr. Metab. 69, 42–51 (2017).
He, Y. Y. et al. The human milk oligosaccharide 2"²-fucosyllactose modulates CD14 expression in human enterocytes, thereby attenuating LPS-induced inflammation. Gut 65, 33–46 (2016).
Lane, J. A., O'Callaghan, J., Carrington, S. D. & Hickey, R. M. Transcriptional response of HT-29 intestinal epithelial cells to human and bovine milk oligosaccharides. Br. J. Nutr. 110, 2127–2137 (2013).
Underwood, M. A., German, J. B., Lebrilla, C. B. & Mills, D. A. Bifidobacterium longum subspecies infantis: Champion colonizer of the infant gut. Pediatr. Res. 77, 229–235 (2015).
Tudehope, D. I. Human milk and the nutritional needs of preterm infants. J. Pediatr. 162, S17-25 (2013).
Quigley, M., Embleton, N. D. & Mcguire, W. Formula versus donor breast milk for feeding preterm or low birth weight infants. Cochrane Database Syst. Rev. 7, CD002971 (2019).
Vieira, A. T., Teixeira, M. M. & Martins, F. S. The role of probiotics and prebiotics in inducing gut immunity. Front. Immunol. 12, 445 (2013).
Dasopoulou, M. et al. Motilin and gastrin secretion and lipid profile in preterm neonates following prebiotics supplementation: A double-blind randomized controlled study. J. Parenter. Enter. Nutr. 39, 359–368 (2015).
Srinivasjois, R., Rao, S. & Patole, S. Prebiotic supplementation in preterm neonates: Updated systematic review and meta-analysis of randomised controlled trials. Clin. Nutr. 32, 958–965 (2013).
Berrington, J. E., Stewart, C. J., Embleton, N. D. & Cummings, S. P. Gut microbiota in preterm infants: assessment and relevance to health and disease. Arch. Dis. Child. Fetal Neonatal Ed. 98, F286-90 (2013).
Kumar, R. K. et al. Optimizing Nutrition in Preterm Low Birth Weight Infants”Consensus Summary. Front. Nutr. 4, 20 (2017).
Mathew, G., Gupta, V., Santhanam, S. & Rebekah, G. Postnatal weight gain patterns in preterm very-low-birth-weight infants born in a tertiary care center in South India. J. Trop. Pediatr. 64, 126–131 (2018).
Fenton, T. R. & Kim, J. H. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatr. 13, (2013).
Indrio, F. et al. Probiotic supplementation in preterm: Feeding intolerance and hospital cost. Nutrients 9, 1–8 (2017).
Chi, C., Buys, N., Li, C., Sun, J. & Yin, C. Effects of prebiotics on sepsis, necrotizing enterocolitis, mortality, feeding intolerance, time to full enteral feeding, length of hospital stay, and stool frequency in preterm infants: a meta-analysis. Eur. J. Clin. Nutr. 73, 657–670 (2019).
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